NeoGenesis MB-2
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MB-2 is the NeoGenesis probiotic occlusive balm for skin that has run out of options: very dry, compromised, visibly disrupted skin that feels tight, itchy or raw.
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Description
Size: 6 g / 55 g
Skin Types: Dry, Sensitive Skin, Mature skin
Skin Concerns: Very dry and compromised skin, visibly disrupted, flaking or tight skin, redness and visible irritation, sensitive and reactive skin, skin stressed during and after professional treatments, final-step occlusive protection
MB-2 is the NeoGenesis rescue step: a probiotic occlusive balm that instantly soothes very dry and compromised skin with immediate barrier and microbiome support from 5 live probiotic bacteria. Castor and hydrogenated castor seed oil form a protective layer that locks in moisture and shields against external irritants, sunflower seed oil replenishes the lipid barrier, and the live strains help balance the skin's microbiome while the skin's own barrier renews itself.
NeoGenesis positions MB-2 for moderate to severe dryness, visibly disrupted skin and skin that is moisture-depleted, stressed or compromised during and after professional treatments. It helps calm the look of redness, flaking, tightness and itching and supports lasting comfort. Warm a small amount between your fingertips, dab it gently onto the area, and use it as the final step over any serums or creams, morning, evening or whenever skin needs it.
Watch: MB-2 explained
NeoGenesis made this short product video for MB-2, so you can see the texture, the application and where it fits in a routine before you buy.
Real results with MB-2
NeoGenesis publishes before and after photos from its professional partners. These cases used MB-2 as part of a NeoGenesis routine, and each caption lists every product involved.
Photos courtesy of NeoGenesis professional partners. Individual results vary.
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Very soothing after microneedling. Apply liberally to calm any itching!
Favorite cleanser. I have purchased it 4 times already and I tried to switch to another brand and I always end up going back to this one. I have very sensitive skin and my pores get clogged very easily. This cream cleanser is soothing and does an excellent job cleansing my face. I use it in the morning and as a second cleanse at time. A little bit goes a long way and although it doesn’t have a scent, the experience of washing your face with it is so pleasant and satisfying. I am done trying new cleansers.
Favorite SPF. I have tried so many different SPF and brands. They would be too greasy and/or sting my eyes after a few hours and/or irritate my sensitive skin and/or clog my pores. I finally found the one! Is it lightweight, non greasy, protects very well, sweat resistant, doesn’t irritate my skin or clog my pores. On top of that a little bit goes a long way. This is my third bottle and my quest for the best SPF for my skin is finally over.
Très bien marché bien et j’achèterais surement un autre
I love this product, the Vivier Sheer SPF30 Mineral tinted sunscreen. I love the creamy easy to apply non scented cream that just glides and covers light skin imperfections. I will definitely re-order again.
I love this product!Used 0.3 before and increased to 0.5 with sude effects.
This cleanser polish is a povely
I’ve been using this product for a year and it’s the only thing that’s worked for my face to help it heal and clear up my skin. I’ve been trying a lot of other products and this one works! Highly recommend!
Very nice, i love this product
Beautiful packaging and looks very high end. I've been using for 2 weeks now and its easy to use. I like how it automatically turns off in 10 mins.
The perfect complement to my pigment control routine - with hydroquinone part of the year, and office laser treatments. This product is excellent, and works well layering. No pilling!
Love this formula! 10/10 great for mature skin
Love this brand already but this was my first time trying these products. A great deal getting them in this kit! My fave is the exfoliating polish, it is amazing! Feels so invigorating, and after my skin feels so soft and fresh.
Excellent product.face mask protection. I visited to Cusco where there is a very high altitude so that the sun radiation is extremely intense. The mask protection worked well!!
I’ve been using this for almost a decade! Love it!
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MB-2: instant barrier and microbiome support in one balm
MB-2 is the NeoGenesis probiotic occlusive balm for skin that has run out of options: very dry, compromised, visibly disrupted skin that feels tight, itchy or raw. It provides immediate barrier and microbiome support from 5 live probiotic bacteria, Bacillus coagulans, Bacillus subtilis, Lactobacillus plantarum, Lactococcus lactis and Lactobacillus crispatus, suspended in castor and sunflower seed oils. The occlusive layer locks in moisture while the skin's own barrier renews itself underneath.
NeoGenesis positions MB-2 for moderate to severe dryness and for skin that is moisture-depleted, stressed or compromised during and after professional treatments. It helps calm the look of redness, flaking, tightness and itching, supports the skin's natural recovery and improves overall comfort, and the live strains help restore balance to the skin's microbiome so sensitivity and recurring visible irritation are less of a pattern. It is always the final step.
Instant barrier support
An occlusive balm that gives immediate soothing comfort and a protective moisture barrier for moderate to severe dryness and visibly disrupted skin.
5 live probiotic strains
Bacillus coagulans, Bacillus subtilis, Lactobacillus plantarum, Lactococcus lactis and Lactobacillus crispatus help restore balance to the skin's natural microbiome.
Calms the look of irritation
Helps soothe the appearance of redness, flaking, tightness and itching while supporting the skin's natural recovery.
Final-step protection
Goes on last, over serums and creams, to lock in moisture and shield against external irritants.
Key Ingredients & How They Work
The actives that drive A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin. — and what each one does for your skin.
Why a probiotic balm
Compromised skin often has an imbalanced microbiome as well as a leaky barrier. Live bacteria encourage flora diversity and natural microbial competition, which NeoGenesis links to calmer, more resilient skin that is less prone to visible irritation and imbalance.
Occlusion done with castor oil
Hydrogenated castor seed oil forms a protective occlusive layer that instantly locks in moisture, limits water loss and shields against external irritants while the skin's natural recovery process continues underneath.
Sunflower seed oil lipids
Rich in essential fatty acids that help replenish and strengthen the skin's natural lipid barrier, improving softness, comfort and overall resilience.
Antioxidant support
Ascorbyl palmitate and tocopheryl acetate, oil-soluble forms of vitamins C and E, round out a short, water-free ingredient list.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin.
What A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin. Pairs Well With
Build a complete routine — these pairings are most often recommended alongside A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin.. Tap any product to shop.
NeoGenesis Barrier Renewal Cream$35.00Shop now →
NeoGenesis Recovery$100.00Shop now →
NeoGenesis Cleanser$30.00Shop now →
NeoGenesis Moisturizing Mist$30.00Shop now →How to Use
- Dispense MB-2 onto your fingertips and rub them together to warm the balm.
- Dab gently onto the area that needs support rather than rubbing it in.
- Use as the final step if layering multiple products. Reapply as often as needed. Available in 6 g and 55 g.
Who It's For
- Very dry, compromised or visibly disrupted skin that needs immediate relief
- Sensitive, reactive skin with recurring visible irritation
- Skin that is moisture-depleted or stressed during and after professional treatments
- Anyone who wants an occlusive final step that also supports the microbiome
Sensitivity note: Made for sensitive and compromised skin, with a short, water-free formula of plant oils, live probiotic strains and vitamins C and E. Apply it over Barrier Renewal Cream or Recovery as the last layer rather than underneath other products.
How A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin. Compares
Where A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin. sits relative to other options. The right fit depends on your skin and goals.
| Feature | NeoGenesis MB-2 | Professional Moisturizers | Drugstore Moisturizers |
|---|---|---|---|
| Microbiome support | 5 live probiotic strains from four genera | One probiotic or a prebiotic extract | None |
| Occlusive base | Castor and hydrogenated castor seed oil with sunflower seed oil | Varies | Petrolatum or mineral oil |
| Who it is made for | Very dry, compromised, post-treatment and reactive skin | General dry skin | General dry skin |
| Where it sits in a routine | Final step over serums and creams, as often as needed | Typically a moisturizer step | Spot use |
A probiotic occlusive balm with 5 live strains that locks in moisture and calms the look of compromised skin.: Frequently Asked Questions
What is a probiotic balm?
A probiotic balm is a skincare product formulated to support the skin's natural microbiome and its protective barrier. NeoGenesis MB-2 combines five live probiotic strains with nourishing castor and sunflower seed oils to reinforce the skin's barrier and lock in moisture.
What does probiotic skincare do for the skin?
MB-2 helps balance the skin's natural microbiome while nourishing dry, sensitive skin. Its blend of live probiotic strains and botanical oils supports the skin barrier and helps reduce the appearance of irritation, sensitivity, itching and flare-ups of redness.
Does a probiotic balm help the skin barrier?
Yes. MB-2 nourishes dry skin while supporting the skin's natural protective barrier. The live probiotic strains, castor oil and sunflower seed oil work together to give lasting moisture while helping skin feel softer, more comfortable and more balanced.
How is MB-2 different from other probiotic skincare?
Many probiotic skincare products rely on a single probiotic ingredient. MB-2 features five live probiotic strains, Bacillus coagulans, Bacillus subtilis, Lactobacillus plantarum, Lactococcus lactis and Lactobacillus crispatus, in an occlusive balm of botanical oils, so it supports the microbiome while delivering long-lasting hydration.
Can I use MB-2 every day?
Yes. MB-2 is formulated for daily use and can be applied as often as needed to keep skin soft, hydrated and comfortable. Regular use helps replenish moisture, support the skin's natural microbiome and reinforce the skin barrier.
When in my routine should I apply MB-2?
Always last. Warm a small amount between your fingertips, dab it gently over the area, and apply it after any serum or cream, such as Recovery or Barrier Renewal Cream. As an occlusive it seals in everything underneath, which is why NeoGenesis calls it the final step.
Are there before and after photos for MB-2?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used MB-2 is shown above with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use MB-2?
Yes. The NeoGenesis product video above walks through MB-2, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
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