NeoGenesis Skin Serum
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Skin Serum brings patented S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, into a lightweight formula made for every day.
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Description
Size: 5 mL / 15 mL / 30 mL / 120 mL
Skin Types: Normal, Dry, Combination, Sensitive Skin
Skin Concerns: Early signs of aging, dry or sensitive skin, visible redness and reactive skin, dry, blemish-prone skin, younger skin, chest, back, hands, arms and body, all skin types
Skin Serum is the everyday NeoGenesis serum, with patented S2RM technology at 20%. NeoGenesis describes it as a daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness. It is the serum for younger skin, early signs of aging, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin, and it is sized for larger areas where skin needs comprehensive support.
Growth factors and matrix-supporting proteins from the S2RM secretome help improve the appearance of firmness and smooth the look of lines, while glycerin and propanediol hydrate and reinforce the skin's natural protective barrier. Gluconolactone, a gentle PHA, helps calm visible irritation. Dermatologist recommended and made for all skin types, it goes on damp skin after cleansing, morning and evening, followed by moisturizer and/or sunscreen. The 120 mL size makes it practical for the chest, back, hands and arms.
Watch: Skin Serum explained
NeoGenesis made this short product video for Skin Serum, so you can see the texture, the application and where it fits in a routine before you buy.
Real results with Skin Serum
NeoGenesis publishes before and after photos from its professional partners. These cases used Skin Serum as part of a NeoGenesis routine, and each caption lists every product involved.
Photos courtesy of NeoGenesis professional partners. Individual results vary.
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Let customers speak for us
Very soothing after microneedling. Apply liberally to calm any itching!
Favorite cleanser. I have purchased it 4 times already and I tried to switch to another brand and I always end up going back to this one. I have very sensitive skin and my pores get clogged very easily. This cream cleanser is soothing and does an excellent job cleansing my face. I use it in the morning and as a second cleanse at time. A little bit goes a long way and although it doesn’t have a scent, the experience of washing your face with it is so pleasant and satisfying. I am done trying new cleansers.
Favorite SPF. I have tried so many different SPF and brands. They would be too greasy and/or sting my eyes after a few hours and/or irritate my sensitive skin and/or clog my pores. I finally found the one! Is it lightweight, non greasy, protects very well, sweat resistant, doesn’t irritate my skin or clog my pores. On top of that a little bit goes a long way. This is my third bottle and my quest for the best SPF for my skin is finally over.
Très bien marché bien et j’achèterais surement un autre
I love this product, the Vivier Sheer SPF30 Mineral tinted sunscreen. I love the creamy easy to apply non scented cream that just glides and covers light skin imperfections. I will definitely re-order again.
I love this product!Used 0.3 before and increased to 0.5 with sude effects.
This cleanser polish is a povely
I’ve been using this product for a year and it’s the only thing that’s worked for my face to help it heal and clear up my skin. I’ve been trying a lot of other products and this one works! Highly recommend!
Very nice, i love this product
Beautiful packaging and looks very high end. I've been using for 2 weeks now and its easy to use. I like how it automatically turns off in 10 mins.
The perfect complement to my pigment control routine - with hydroquinone part of the year, and office laser treatments. This product is excellent, and works well layering. No pilling!
Love this formula! 10/10 great for mature skin
Love this brand already but this was my first time trying these products. A great deal getting them in this kit! My fave is the exfoliating polish, it is amazing! Feels so invigorating, and after my skin feels so soft and fresh.
Excellent product.face mask protection. I visited to Cusco where there is a very high altitude so that the sun radiation is extremely intense. The mask protection worked well!!
I’ve been using this for almost a decade! Love it!
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Skin Serum: 20% S2RM, the daily essential for face and body
Skin Serum brings patented S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, into a lightweight formula made for every day. At 20% it is the gentlest concentration in the NeoGenesis serum family, and NeoGenesis calls it the daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness, with growth factors and matrix-supporting proteins working alongside humectants and a gentle PHA.
It is the serum NeoGenesis recommends for younger skin, early signs of aging, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin. Because it comes in sizes up to 120 mL, it is also the practical choice for larger surfaces such as the chest, back, hands and arms. Dermatologist recommended and made for all skin types, it goes on damp skin after cleansing, morning and evening, under moisturizer and sunscreen.
20% S2RM, every day
The gentlest S2RM concentration in the line, formulated for consistent morning and evening use.
Calms the look of redness
Supports compromised skin by soothing the appearance of irritation and helping skin look less reactive over time.
Hydrates and supports the barrier
Glycerin and propanediol hydrate, help reduce water loss and reinforce the skin's natural protective barrier.
Face and body
Available up to 120 mL for the chest, back, hands, arms and anywhere else that needs comprehensive support.
Key Ingredients & How They Work
The actives that drive 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging. — and what each one does for your skin.
The S2RM secretome
Stem cell released molecules from fibroblast and adipose mesenchymal stem cells, including exosomes, ectosomes and the soluble fraction, support the skin's natural renewal process.
Firmness and lines
Growth factors and matrix-supporting proteins help improve the appearance of skin firmness and smooth the look of lines and wrinkles.
Humectant hydration
Glycerin and propanediol draw in water and help reduce transepidermal water loss, supporting a comfortable, resilient barrier.
A gentle PHA
Gluconolactone refines and soothes the skin, brings antioxidant properties and helps calm visible irritation in sensitive or compromised skin.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging.
What 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging. Pairs Well With
Build a complete routine — these pairings are most often recommended alongside 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging.. Tap any product to shop.
NeoGenesis Light Moisturizer$30.00Shop now →
NeoGenesis Barrier Renewal Cream$35.00Shop now →
NeoGenesis MB-2$45.00Shop now →
NeoGenesis Salicylic Acid Gel$65.00Shop now →How to Use
- After cleansing, apply Skin Serum to damp skin, on the face or on larger areas such as the chest, back, hands and arms.
- Follow with any additional serums, then immediately apply moisturizer and/or sunscreen.
- Use morning and evening for consistent results.
Who It's For
- Younger skin and early signs of aging
- Dry or sensitive skin, including dry redness-prone skin
- Dry, blemish-prone skin
- Anyone who wants S2RM support on larger areas of the body
Sensitivity note: Made for all skin types and frequently recommended by skincare professionals for dry, sensitive skin. It is fragrance free, retinoid free and built around humectants and a gentle PHA, so it can be used morning and evening from the first day.
How 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging. Compares
Where 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging. sits relative to other options. The right fit depends on your skin and goals.
| Feature | NeoGenesis Skin Serum | Other Growth Factor Serums | Drugstore Serums |
|---|---|---|---|
| Active technology | Patented S2RM at 20%, the complete secretome from two stem cell sources | One growth factor or a narrow blend | Hydrators only, no growth factor content |
| Best for | Early aging, sensitive and redness-prone skin, daily maintenance, body | Usually firmness in mature skin | Basic hydration |
| Sizes | 5 mL to 120 mL, practical for face and larger areas | Typically 30 mL face only | Varies |
| Routine fit | Damp skin after cleansing, AM and PM, layers under other serums | Once or twice daily | Once or twice daily |
20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging.: Frequently Asked Questions
What is NeoGenesis Skin Serum?
Skin Serum is the everyday NeoGenesis serum, featuring patented S2RM technology at 20%. S2RM means stem cell released molecules, the complete secretome from human fibroblast and adipose mesenchymal stem cells. NeoGenesis describes it as a daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness in a lightweight, versatile formula.
How do I use Skin Serum?
After cleansing, apply Skin Serum to damp skin. Follow with any additional serums, then immediately apply moisturizer and/or sunscreen. Use it morning and evening. It comes in 5 mL, 15 mL, 30 mL and 120 mL, and the larger size is meant for areas like the chest, back, hands and arms.
Who is Skin Serum best for?
NeoGenesis recommends Skin Serum for younger skin, early signs of aging, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin. It is also the brand's pick for larger areas of the body where maintaining skin quality is a priority. It is dermatologist recommended and made for all skin types.
How is Skin Serum different from Recovery and Booster?
They share the same S2RM technology at different concentrations. Recovery is 70%, the highest potency, for correction and for skin that is stressed or compromised. Booster is 40% with a bioavailable hyaluronic acid and amino acids, for dryness, fine lines and firmness. Skin Serum is 20%, the lightest option, made for daily maintenance, early signs of aging, sensitive skin and the body.
Is Skin Serum good for preventative aging?
Yes. NeoGenesis positions it as the serum for maintaining skin before deeper lines and more advanced changes develop. It supports the skin's natural renewal process while improving the appearance of early fine lines, uneven texture, visible redness and overall skin quality, which makes it a sensible long-term daily serum.
How long until I see results?
NeoGenesis does not publish a fixed timeline for Skin Serum. The brand's guidance is consistent use, morning and evening, because the benefits to early signs of aging, uneven texture and visible redness build with daily application. Hydration and comfort are the first things most people notice.
Can I use Skin Serum with retinoids, vitamin C or exfoliating acids?
Yes. NeoGenesis designs its targeted products, including Skin Restore Serum (vitamin A), Vibrant C Serum, Salicylic Acid Gel and Mandelic Acid 8%, to be applied after an S2RM serum. Apply Skin Serum to damp skin first, layer the active over it, then finish with moisturizer and/or sunscreen. Use sunscreen daily when exfoliating acids are in the routine.
Are there before and after photos for Skin Serum?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Skin Serum is shown above with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use Skin Serum?
Yes. The NeoGenesis product video above walks through Skin Serum, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
Explore Related Concerns & Ingredients
The concern and ingredient hubs 20% S2RM for everyday use: hydrates, calms the look of redness and supports early signs of aging. most often appears in at WeDoSkin.
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