NeoGenesis Intensive Moisturizer
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Intensive Moisturizer is the NeoGenesis cream for normal to dry skin, and the one skincare professionals reach for in dry climates and colder months.
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Description
Size: 5 mL / 30 mL / 120 mL
Skin Types: Normal, Dry, Sensitive Skin, Mature skin
Skin Concerns: Normal to dry skin, dry, dehydrated and depleted skin, mature skin and visible signs of aging, dry climates and colder months, skin that is stressed or compromised by professional treatments, reactive skin that needs lipid replenishment, skin that feels tight, rough or uncomfortable
Intensive Moisturizer is the NeoGenesis moisturizer for normal to dry skin, and the one to reach for in dry climates and colder months. It is powered by 5% S2RM, stem cell released molecules, a nourishing blend of growth factors, heat shock proteins, immune modulators and antioxidants that supports the skin's natural recovery and renewal processes and helps improve overall tone and texture. Dermatologist recommended and made for all skin types.
Around the S2RM sits a lipid-rich base: safflower oleosomes, squalane and triglycerides soften skin and reduce transepidermal water loss, urea, sodium hyaluronate and glycerin replenish hydration, and CoQ10 and vitamin E add antioxidant support. It deeply hydrates, replenishes the skin's oil levels, supports the barrier and comfort, and promotes a more youthful-looking complexion. Apply one pump morning and evening after your S2RM serum, plus one for neck and decollete. Available in 5 mL, 30 mL and 120 mL.
Watch: Intensive Moisturizer explained
NeoGenesis made this short product video for Intensive Moisturizer, so you can see the texture, the application and where it fits in a routine before you buy.
Real results with Intensive Moisturizer
NeoGenesis publishes before and after photos from its professional partners. These cases used Intensive Moisturizer as part of a NeoGenesis routine, and each caption lists every product involved.
Photos courtesy of NeoGenesis professional partners. Individual results vary.
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Let customers speak for us
Very soothing after microneedling. Apply liberally to calm any itching!
Favorite cleanser. I have purchased it 4 times already and I tried to switch to another brand and I always end up going back to this one. I have very sensitive skin and my pores get clogged very easily. This cream cleanser is soothing and does an excellent job cleansing my face. I use it in the morning and as a second cleanse at time. A little bit goes a long way and although it doesn’t have a scent, the experience of washing your face with it is so pleasant and satisfying. I am done trying new cleansers.
Favorite SPF. I have tried so many different SPF and brands. They would be too greasy and/or sting my eyes after a few hours and/or irritate my sensitive skin and/or clog my pores. I finally found the one! Is it lightweight, non greasy, protects very well, sweat resistant, doesn’t irritate my skin or clog my pores. On top of that a little bit goes a long way. This is my third bottle and my quest for the best SPF for my skin is finally over.
Très bien marché bien et j’achèterais surement un autre
I love this product, the Vivier Sheer SPF30 Mineral tinted sunscreen. I love the creamy easy to apply non scented cream that just glides and covers light skin imperfections. I will definitely re-order again.
I love this product!Used 0.3 before and increased to 0.5 with sude effects.
This cleanser polish is a povely
I’ve been using this product for a year and it’s the only thing that’s worked for my face to help it heal and clear up my skin. I’ve been trying a lot of other products and this one works! Highly recommend!
Very nice, i love this product
Beautiful packaging and looks very high end. I've been using for 2 weeks now and its easy to use. I like how it automatically turns off in 10 mins.
The perfect complement to my pigment control routine - with hydroquinone part of the year, and office laser treatments. This product is excellent, and works well layering. No pilling!
Love this formula! 10/10 great for mature skin
Love this brand already but this was my first time trying these products. A great deal getting them in this kit! My fave is the exfoliating polish, it is amazing! Feels so invigorating, and after my skin feels so soft and fresh.
Excellent product.face mask protection. I visited to Cusco where there is a very high altitude so that the sun radiation is extremely intense. The mask protection worked well!!
I’ve been using this for almost a decade! Love it!
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Intensive Moisturizer: 5% S2RM for skin that needs real moisture
Intensive Moisturizer is the NeoGenesis cream for normal to dry skin, and the one skincare professionals reach for in dry climates and colder months. It is powered by 5% S2RM, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells: a nourishing blend of growth factors, heat shock proteins, immune modulators and antioxidants that supports the skin's natural recovery and renewal processes and helps improve overall tone and texture. NeoGenesis calls this promoting skin longevity.
The base is where the moisture comes from. Safflower oleosomes, squalane and triglycerides soften skin and reduce transepidermal water loss, urea, sodium hyaluronate and glycerin replenish hydration, and CoQ10 and vitamin E add antioxidant support. Together they replenish the skin's oil levels, support the barrier and comfort, and hydrate and calm skin that is depleted, stressed or compromised by professional treatments. Apply one pump morning and evening after your S2RM serum, with an extra pump for neck and decollete.
5% S2RM inside
Growth factors, heat shock proteins, immune modulators and antioxidants that support recovery, renewal, tone and texture.
Rich moisture for dry skin
Replenishes the skin's oil levels and supports comfort and resilience, even in dry climates and cold weather.
Calms compromised skin
Hydrates and calms skin that is depleted of moisture, stressed or compromised by professional treatments.
Lipids without grease
Safflower oleosomes, squalane and triglycerides soften skin and reduce water loss while feeling comfortable, not heavy.
Key Ingredients & How They Work
The actives that drive 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin. — and what each one does for your skin.
S2RM in a moisturizer
Human fibroblast and adipose mesenchymal stem cell conditioned media, at 5%, delivers the stem cell released molecules NeoGenesis is known for, so the moisturizer supports renewal rather than just coating the surface.
Oleosomes and squalane
Safflower oil oleosomes, squalane and caprylic/capric triglyceride replenish lipids and reduce transepidermal water loss (TEWL), leaving skin soft and comfortable without a greasy finish.
Layered hydration
Urea, glycerin and high molecular weight sodium hyaluronate work together to replenish water in the skin and improve texture, backed by chondrus crispus (red algae) extract.
CoQ10 and vitamin E
Ubiquinone replenishes the skin's CoQ10 to help energize cells and provide antioxidant support, while tocopheryl acetate adds further antioxidant protection for skin longevity.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin.
What 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin. Pairs Well With
Build a complete routine — these pairings are most often recommended alongside 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin.. Tap any product to shop.
NeoGenesis Recovery$100.00Shop now →
NeoGenesis Skin Serum$55.00Shop now →
NeoGenesis MB-2$45.00Shop now →
NeoGenesis Moisturizing Mist$30.00Shop now →How to Use
- Cleanse, then apply your S2RM serum (Recovery, Booster or Skin Serum).
- Apply 1 pump of Intensive Moisturizer to the face morning and evening, and an additional pump to the neck and decollete.
- Follow with sunscreen during the day. Many people favor it in the evening, when skin goes through its natural overnight renewal.
Who It's For
- Normal to dry skin, especially in dry climates and colder months
- Mature skin with visible signs of aging that wants lipid replenishment and S2RM support
- Dehydrated or environmentally stressed skin that feels tight, rough or depleted
- Skin that is stressed or compromised by professional treatments and needs comfort and calm
Sensitivity note: Made for all skin types and positioned by NeoGenesis for compromised, stressed and reactive skin as well as dry skin. If your skin is oily or combination, the lighter NeoGenesis Light Moisturizer may be the better fit; if the barrier is the main concern, see Barrier Renewal Cream.
How 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin. Compares
Where 5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin. sits relative to other options. The right fit depends on your skin and goals.
| Feature | NeoGenesis Intensive Moisturizer | Professional Moisturizers | Drugstore Moisturizers |
|---|---|---|---|
| Active technology | 5% S2RM: growth factors, heat shock proteins, immune modulators, antioxidants | Peptides or a single growth factor | None, hydrators only |
| Lipid replenishment | Safflower oleosomes, squalane and triglycerides, non-greasy | Varies by formula | Often mineral oil or heavy occlusives |
| Hydration | Urea, glycerin and high molecular weight hyaluronic acid | Usually hyaluronic acid alone | Glycerin, sometimes hyaluronic acid |
| Who it suits | Dry, mature, dehydrated and compromised skin, all skin types | Varies | Varies, often fragranced |
5% S2RM in a rich, lipid-replenishing cream for dry, aging and compromised skin.: Frequently Asked Questions
What is NeoGenesis Intensive Moisturizer?
It is the NeoGenesis moisturizer for normal to dry skin, designed to deeply hydrate, replenish essential lipids and support skin that looks and feels at its best. Powered by 5% S2RM technology, it restores comfort, improves softness and promotes long-lasting hydration for dry, mature and environmentally stressed skin.
Is Intensive Moisturizer good for dry skin and dry climates?
Yes, that is exactly what NeoGenesis built it for. It provides rich moisture that replenishes the skin's oil levels and supports comfort and resilience, and the brand recommends it especially in colder months, in dry climates, or whenever skin feels tight, rough or depleted.
What makes Intensive Moisturizer different from other rich creams?
Most rich moisturizers simply coat the skin's surface. Intensive Moisturizer combines safflower oleosomes, squalane, urea, sodium hyaluronate, CoQ10 and vitamin E with regenerative 5% S2RM technology, so it hydrates and replenishes lipids while supporting the skin's natural recovery and renewal for a softer, smoother complexion.
Intensive Moisturizer or Barrier Renewal Cream: which do I need?
Intensive Moisturizer is formulated for dry, mature and dehydrated skin that needs long-lasting hydration and lipid replenishment. Barrier Renewal Cream is formulated for compromised, sensitized and post-procedure skin where restoring barrier function is the primary goal. If dryness is the main issue, start here.
Should I use Intensive Moisturizer in the morning or at night?
Either, or both, depending on your skin's hydration needs. NeoGenesis notes that many people enjoy it in the evening to replenish moisture while the skin goes through its natural overnight renewal. In the morning, follow it with sunscreen.
How do I use Intensive Moisturizer with the NeoGenesis serums?
Cleanse, apply your S2RM serum (Recovery, Booster or Skin Serum), then apply one pump of Intensive Moisturizer to the face and an additional pump to the neck and decollete. Use morning and evening, with sunscreen during the day. NeoGenesis also pairs it with Moisturizing Mist and MB-2 Probiotic Balm.
Are there before and after photos for Intensive Moisturizer?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Intensive Moisturizer is shown above with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use Intensive Moisturizer?
Yes. The NeoGenesis product video above walks through Intensive Moisturizer, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
Explore Related Concerns & Ingredients
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