Canada’s Most Trusted Medical-Grade Skincare

Collection: Canada’s Most Trusted Medical-Grade Skincare

Clinically proven, dermatologist-trusted products chosen by real patients and leading Canadian skincare professionals.

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Canada’s Top Medical-Grade Skincare Bestsellers

Explore the most trusted clinical-strength skincare products chosen by dermatology patients, medical spas and real users across Canada. These formulations deliver consistent, measurable results for concerns including aging, pigmentation, acne, hydration and skin barrier health. Curated from our highest-performing brands such as Vivier, ZO Skin Health, AlumierMD, SkinMedica, Colorescience and more.

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484 products
  • Esthederm Intensive Spiruline Serum
    Esthederm Intensive Spiruline Serum Esthederm Intensive Spiruline Serum

    Esthederm Intensive Spiruline Serum

    Regular price
    $116.00
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    $116.00
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  • Esthederm Intensive Spiruline Cream
    Esthederm Intensive Spiruline Cream Esthederm Intensive Spiruline Cream

    Esthederm Intensive Spiruline Cream

    Regular price
    $110.00
    Sale price
    $110.00
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  • Esthederm Intensive Retinol Eye Lifting Effect Balm
    Esthederm Intensive Retinol Eye Lifting Effect Balm Esthederm Intensive Retinol Eye Lifting Effect Balm

    Esthederm Intensive Retinol Eye Lifting Effect Balm

    Regular price
    $76.00
    Sale price
    $76.00
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  • Esthederm Intensive Propolis+ Ferulic Acid Skin Perfecting Cream
    Esthederm Intensive Propolis+ Ferulic Acid Skin Perfecting Cream Esthederm Intensive Propolis+ Ferulic Acid Skin Perfecting Cream

    Esthederm Intensive Propolis+ Ferulic Acid Skin Perfecting Cream

    Regular price
    $76.00
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    $76.00
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  • Esthederm Intensive Propolis+ Kaolin Purifying Mask
    Esthederm Intensive Propolis+ Kaolin Purifying Mask Esthederm Intensive Propolis+ Kaolin Purifying Mask

    Esthederm Intensive Propolis+ Kaolin Purifying Mask

    Regular price
    $74.00
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    $74.00
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  • Esthederm Intensive Propolis+ Zinc Serum-Lotion
    Esthederm Intensive Propolis+ Zinc Serum-Lotion Esthederm Intensive Propolis+ Zinc Serum-Lotion

    Esthederm Intensive Propolis+ Zinc Serum-Lotion

    Regular price
    $56.00
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    $56.00
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  • Esthederm Intensive Hyaluronic Eye Contour Serum
    Esthederm Intensive Hyaluronic Eye Contour Serum Esthederm Intensive Hyaluronic Eye Contour Serum

    Esthederm Intensive Hyaluronic Eye Contour Serum

    Regular price
    $76.00
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    $76.00
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  • Esthederm E.V.E. Serum Source
    Esthederm E.V.E. Serum Source Esthederm E.V.E. Serum Source

    Esthederm E.V.E. Serum Source

    Regular price
    $145.00
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    $145.00
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  • Esthederm Brightening Youth Serum
    Esthederm Brightening Youth Serum Esthederm Brightening Youth Serum

    Esthederm Brightening Youth Serum

    Regular price
    $126.00
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    $126.00
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  • Esthederm Cellular Water Melting Moisturizing Cream
    Esthederm Cellular Water Melting Moisturizing Cream Esthederm Cellular Water Melting Moisturizing Cream

    Esthederm Cellular Water Melting Moisturizing Cream

    Regular price
    $70.00
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    $70.00
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  • Esthederm Cellular Water Mist
    Esthederm Cellular Water Mist Esthederm Cellular Water Mist

    Esthederm Cellular Water Mist

    Regular price
    $38.00
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    $38.00
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  • Esthederm Cellular Water Gentle Body Scrub
    Esthederm Cellular Water Gentle Body Scrub

    Esthederm Cellular Water Gentle Body Scrub

    Regular price
    $38.00
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    $38.00
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  • Esthederm Derm Repair Restructuring Serum
    Esthederm Derm Repair Restructuring Serum Esthederm Derm Repair Restructuring Serum

    Esthederm Derm Repair Restructuring Serum

    Regular price
    $127.00
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    $127.00
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  • Esthederm Active Repair Wrinkle Correction Cream
    Esthederm Active Repair Wrinkle Correction Cream Esthederm Active Repair Wrinkle Correction Cream

    Esthederm Active Repair Wrinkle Correction Cream

    Regular price
    $119.00
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    $119.00
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  • Lips to Lashes Holiday Set
    Lips to Lashes Holiday Set Lips to Lashes Holiday Set
    $53.00 Off

    Lips to Lashes Holiday Set

    Regular price
    $205.00
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    $205.00
    Regular price
    $258.00
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  • GM Collin Peel Toner Exfoliant
    GM Collin Peel Toner Exfoliant GM Collin Peel Toner Exfoliant

    GM Collin Peel Toner Exfoliant

    Regular price
    $80.00
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    $80.00
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  • GM Collin Dark Spot Serum
    GM Collin Dark Spot Serum GM Collin Dark Spot Serum

    GM Collin Dark Spot Serum

    Regular price
    $110.00
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    $110.00
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  • Colorescience Total Lash™ Mascara
    Colorescience Total Lash™ Mascara Colorescience Total Lash™ Mascara

    Colorescience Total Lash™ Mascara

    Regular price
    $79.90
    Sale price
    $79.90
    Regular price
    $79.90
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  • Colorescience Total Eye® Concentrate Serum Rollerball
    Colorescience Total Eye® Concentrate Serum Rollerball Colorescience Total Eye® Concentrate Serum Rollerball

    Colorescience Total Eye® Concentrate Serum Rollerball

    Regular price
    $98.00
    Sale price
    $98.00
    Regular price
    $98.00
    Earn 5% Cashback
  • Colorescience Lip Shine Peptide - Savanna
    Colorescience Lip Shine Peptide - Savanna Colorescience Lip Shine Peptide - Savanna

    Colorescience Lip Shine Peptide - Savanna

    Regular price
    $52.00
    Sale price
    $52.00
    Regular price
    $52.00
    Earn 5% Cashback
  • Colorescience All Calm Multi-Correction Serum
    Colorescience All Calm Multi-Correction Serum Colorescience All Calm Multi-Correction Serum

    Colorescience All Calm Multi-Correction Serum

    Regular price
    $129.90
    Sale price
    $129.90
    Regular price
    $129.90
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  • Omnilux Squalane Jelly Moisturizer
    Omnilux Squalane Jelly Moisturizer Omnilux Squalane Jelly Moisturizer
    $11.40 Off

    Omnilux Squalane Jelly Moisturizer

    Regular price
    $64.60
    Sale price
    $64.60
    Regular price
    $76.00
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  • Omnilux Salicylic Acid Cleanser
    Omnilux Salicylic Acid Cleanser Omnilux Salicylic Acid Cleanser
    $8.70 Off

    Omnilux Salicylic Acid Cleanser

    Regular price
    $49.30
    Sale price
    $49.30
    Regular price
    $58.00
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🏆 2026 Canadian Clinical Skincare Awards
Recognizing the most trusted, dermatologist-approved, professional-grade skincare brands leading Canada’s results-driven skin health movement.

Top 10 Medical-Grade & Professional Skincare Brands in Canada (2026)

Medical-grade skincare in Canada continues to rise sharply as dermatologists, medical spas and regulated skincare clinics emphasize professional-strength formulations with clinically validated results. Between 2024 and 2026, these brands have emerged as the most trusted, high-performing, and evidence-backed lines in the country.

This list is based on Canadian professional recommendations, clinic adoption across dermatology offices, measured client outcomes, scientific innovation and consistency in product performance. It highlights the brands most used by working professionals for pigmentation, aging, sensitivity, barrier repair, acne and preventative care.

Whether you are searching for medical-grade skincare, professional-grade skincare or dermatologist-approved skincare brands, this 2026 guide represents Canada’s most effective and results-driven product lines.

At a Glance: Canada’s Most Awarded Clinical Skincare Brands

Brand Trend Status 2026 Avg Price (CAD) Popular Age Group Hero Focus / Why It Leads
Vivier 🇨🇦
Winner: Best Clinical Vitamin C System (Canada)
Trending upward - Vitamin C category leader $$ - $$$ 30 - 60 Pharmaceutical-grade USP Vitamin C + peptides for brightening & strengthening. Shop Vivier
AlumierMD 🇨🇦/🇺🇸
Winner: Best Clean Clinical Skincare Brand
Rising - Clean, dermatologist-dispensed innovation $$ 25 - 55 Fragrance-free, dermatologist-formulated systems balancing antioxidants, exfoliants and retinoids. Shop AlumierMD
G.M. COLLIN 🇨🇦
Winner: Best Professional Spa-Clinical Hybrid Brand
Steady - Barrier repair & peptide science $$ 35 - 65 Collagen-supporting peptide systems with clinical hydration. Shop G.M. COLLIN
ZO Skin Health 🇺🇸
Winner: Best Professional Retinol Program
Leading - Aggressive correction & transformation $$$ 28 - 60 High-strength retinol and exfoliation systems for texture, tone and resilience. Shop ZO
SkinCeuticals 🇺🇸
Winner: Best Antioxidant Serum (Global)
Consistent - Antioxidant excellence $$$ 25 - 55 CE Ferulic antioxidant systems trusted worldwide.
SkinMedica 🇺🇸
Winner: Best Growth Factor Technology
Growing - Collagen & repair technology $$$ - $$$$ 35 - 65 Advanced growth factor & peptide serums. Shop SkinMedica
Obagi Medical 🇺🇸
Winner: Best Pigment-Correcting System
Classic - Protocol-based transformation $$$ 30 - 65 Retinol + pigment control systems for deep correction. Shop Obagi
Alastin Skincare 🇺🇸
Winner: Best Post-Procedure Skincare
Emerging - Collagen & recovery leader $$$ - $$$$ 35 - 65 Pre- & post-procedure collagen support.
Epionce 🇺🇸
Winner: Best Barrier Repair Brand
Niche - Dermatologist-created barrier science $$ 25 - 55 Botanical barrier-first formulations.
Revision Skincare 🇺🇸
Winner: Best Neck & Décolleté Formula
Increasing - Texture & firming expertise $$$ 40 - 70 Advanced tightening & peptide systems.

Key Clinical Skincare Trends Defining 2026

  • Multi-brand routines dominate: Canadians combine Vivier Vitamin C + ZO retinol + AlumierMD hydration.
  • Sustainable clinical packaging: Vivier and AlumierMD lead eco-conscious professional skincare.
  • Post-procedure systems expanding: SkinMedica and Alastin drive medical aftercare protocols.
  • Ingredient literacy rising: Clinics educate users on actives, improving compliance.

Choosing Brands by Age & Skin Needs

  1. Under 30: Preventative antioxidants (Vivier, AlumierMD, SkinCeuticals)
  2. 30 - 45: Brightening + retinoids (ZO, AlumierMD, G.M. Collin)
  3. 45 - 60: Growth factors + peptides (SkinMedica, Vivier, Alastin)
  4. 60+: Hydration + collagen maintenance (G.M. Collin, Revision)

Frequently Asked Questions

What defines medical-grade skincare?
Medical-grade skincare uses clinically validated actives with proven results, manufactured under pharmaceutical standards.
Which brand offers the best value?
G.M. Collin and AlumierMD offer strong daily-use performance in the 100 to 150 CAD range.
Can I combine brands in one routine?
Yes. Many Canadians pair Vivier Vitamin C with ZO retinol and SkinMedica or AlumierMD hydration to build a customized regimen.
Where can I buy authentic dermatologist-approved skincare?
You can purchase authentic, clinic-approved brands directly from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.