Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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498 products
  • PCA Creamy Cleanser
    PCA Creamy Cleanser PCA Creamy Cleanser

    PCA Creamy Cleanser

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    $56.00
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    $56.00
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    $56.00
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  • EltaMD Renew Eye Gel
    EltaMD Renew Eye Gel EltaMD Renew Eye Gel

    EltaMD Renew Eye Gel

    Regular price
    $134.00
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    $134.00
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    $134.00
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  • ZO Skin Health Renewal Crème
    ZO Skin Health Renewal Crème ZO Skin Health Renewal Crème

    ZO Skin Health Renewal Crème

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    $160.00
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    $160.00
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  • SkinBetter Even Tone Correcting Serum
    SkinBetter Even Tone Correcting Serum SkinBetter Even Tone Correcting Serum

    SkinBetter Even Tone Correcting Serum

    Regular price
    $220.00
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    $220.00
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  • ZO Skin Health Enzymatic Peel
    ZO Skin Health Enzymatic Peel

    ZO Skin Health Enzymatic Peel

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    $115.00
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    $115.00
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  • Youth Complex
    Youth Complex Youth Complex

    Youth Complex

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    $229.00
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    $229.00
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    $229.00
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  • iS Clinical LIProtect SPF 35
    iS Clinical LIProtect SPF 35 iS Clinical LIProtect SPF 35

    iS Clinical LIProtect SPF 35

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    $35.00
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    $35.00
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    $35.00
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  • PCA Skin Facial Wash Oily/Problem
    PCA Skin Facial Wash Oily/Problem PCA Skin Facial Wash Oily/Problem

    PCA Skin Facial Wash Oily/Problem

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    $56.00
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    $56.00
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    $56.00
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  • PCA Skin Intensive Age Refining Treatment
    PCA Skin Intensive Age Refining Treatment PCA Skin Intensive Age Refining Treatment

    PCA Skin Intensive Age Refining Treatment

    Regular price
    $174.00
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    $174.00
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    $174.00
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  • PCA Skin Hydramatte
    PCA Skin Hydramatte PCA Skin Hydramatte

    PCA Skin Hydramatte

    Regular price
    $147.00
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    $147.00
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    $147.00
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  • PCA Skin Exlinea Pro Peptide Serum
    PCA Skin Exlinea Pro Peptide Serum PCA Skin Exlinea Pro Peptide Serum

    PCA Skin Exlinea Pro Peptide Serum

    Regular price
    $221.00
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    $221.00
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    $221.00
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  • SkinCeuticals Physical Matte UV Defense SPF 50
    SkinCeuticals Physical Matte UV Defense SPF 50 SkinCeuticals Physical Matte UV Defense SPF 50

    SkinCeuticals Physical Matte UV Defense SPF 50

    Regular price
    $55.00
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    $55.00
    Regular price
    $55.00
  • SkinCeuticals A.G.E. Interrupter Advanced Sample (3ml)
    SkinCeuticals A.G.E. Interrupter Advanced Sample (3ml)

    SkinCeuticals A.G.E. Interrupter Advanced Sample (3ml)

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  • SkinCeuticals Retexturing Activator
    SkinCeuticals Retexturing Activator SkinCeuticals Retexturing Activator

    SkinCeuticals Retexturing Activator

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    $120.00
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    $120.00
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    $120.00
  • SkinCeuticals Silymarin CF
    SkinCeuticals Silymarin CF SkinCeuticals Silymarin CF

    SkinCeuticals Silymarin CF

    Regular price
    $220.00
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    $220.00
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    $220.00
  • SkinCeuticals Tripeptide-R Neck Repair
    SkinCeuticals Tripeptide-R Neck Repair SkinCeuticals Tripeptide-R Neck Repair

    SkinCeuticals Tripeptide-R Neck Repair

    Regular price
    $170.00
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    $170.00
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    $170.00
  • SkinCeuticals Simply Clean
    SkinCeuticals Simply Clean SkinCeuticals Simply Clean

    SkinCeuticals Simply Clean

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    $62.00
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    $62.00
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    $62.00
  • SkinCeuticals Serum 10 AOX+
    SkinCeuticals Serum 10 AOX+ SkinCeuticals Serum 10 AOX+

    SkinCeuticals Serum 10 AOX+

    Regular price
    $130.00
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    $130.00
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    $130.00
  • SkinCeuticals Resveratrol B E
    SkinCeuticals Resveratrol B E SkinCeuticals Resveratrol B E

    SkinCeuticals Resveratrol B E

    Regular price
    $220.00
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    $220.00
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    $220.00
  • SkinCeuticals Antioxidant Lip Repair
    SkinCeuticals Antioxidant Lip Repair SkinCeuticals Antioxidant Lip Repair

    SkinCeuticals Antioxidant Lip Repair

    Regular price
    $60.00
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    $60.00
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    $60.00
  • SkinCeuticals Triple Lipid Restore 2:4:2
    SkinCeuticals Triple Lipid Restore 2:4:2 SkinCeuticals Triple Lipid Restore 2:4:2

    SkinCeuticals Triple Lipid Restore 2:4:2

    Regular price
    $190.00
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    $190.00
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    $190.00
  • SkinCeuticals Retinol 0.5
    SkinCeuticals Retinol 0.5 SkinCeuticals Retinol 0.5

    SkinCeuticals Retinol 0.5

    Regular price
    $115.00
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    $115.00
    Regular price
    $115.00
  • SkinCeuticals Retinol 0.3
    SkinCeuticals Retinol 0.3 SkinCeuticals Retinol 0.3

    SkinCeuticals Retinol 0.3

    Regular price
    $105.00
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    $105.00
    Regular price
    $105.00

Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.