Canada’s Most Trusted Medical-Grade Skincare

Collection: Canada’s Most Trusted Medical-Grade Skincare

Clinically proven, dermatologist-trusted products chosen by real patients and leading Canadian skincare professionals.

Authorized Retailer

Free Shipping over $99

Earn cashback on every purchase

Free samples with every order

Canada’s Top Medical-Grade Skincare Bestsellers

Explore the most trusted clinical-strength skincare products chosen by dermatology patients, medical spas and real users across Canada. These formulations deliver consistent, measurable results for concerns including aging, pigmentation, acne, hydration and skin barrier health. Curated from our highest-performing brands such as Vivier, ZO Skin Health, AlumierMD, SkinMedica, Colorescience and more.

Showing 484 of 484 products

Sort by:
Brand
0 selected Reset
Product type
0 selected Reset
Filter and sort

Filter and sort

484 products

Brand
Product type
484 products
  • ZO Skin Health Pigment Control Crème 2% HQ
    ZO Skin Health Pigment Control Crème 2% HQ

    ZO Skin Health Pigment Control Crème 2% HQ

    Regular price
    $107.00
    Sale price
    $107.00
    Regular price
    Earn 5% Cashback
  • Institut Esthederm Cellular Water Mist
    Institut Esthederm Cellular Water Mist Institut Esthederm Cellular Water Mist

    Institut Esthederm Cellular Water Mist

    Regular price
    $48.00
    Sale price
    $48.00
    Regular price
    Earn 5% Cashback
  • GM Collin Hydramucine Cleansing Milk
    GM Collin Hydramucine Cleansing Milk GM Collin Hydramucine Cleansing Milk

    GM Collin Hydramucine Cleansing Milk

    Regular price
    $50.00
    Sale price
    $50.00
    Regular price
    Earn 5% Cashback
  • GM Collin Phyto Stem Cell Eye Contour Cream
    GM Collin Phyto Stem Cell Eye Contour Cream GM Collin Phyto Stem Cell Eye Contour Cream

    GM Collin Phyto Stem Cell Eye Contour Cream

    Regular price
    $105.00
    Sale price
    $105.00
    Regular price
    Earn 5% Cashback
  • Omnilux Eye Brightener Hydrocolloid Refill Patches (20 pack)
    Omnilux Eye Brightener Hydrocolloid Refill Patches (20 pack) Omnilux Eye Brightener Hydrocolloid Refill Patches (20 pack)
    $9.60 Off

    Omnilux Eye Brightener Hydrocolloid Refill Patches (20 pack)

    Regular price
    $54.40
    Sale price
    $54.40
    Regular price
    $64.00
    Earn 5% Cashback
  • Omnilux Hyaluronic Acid Serum
    Omnilux Hyaluronic Acid Serum Omnilux Hyaluronic Acid Serum
    $10.80 Off

    Omnilux Hyaluronic Acid Serum

    Regular price
    $61.20
    Sale price
    $61.20
    Regular price
    $72.00
    Earn 5% Cashback
  • ZO Skin Health Retinol Skin Brightener 1%
    ZO Skin Health Retinol Skin Brightener 1% ZO Skin Health Retinol Skin Brightener 1%

    ZO Skin Health Retinol Skin Brightener 1%

    Regular price
    From $125.00
    Sale price
    From $125.00
    Regular price
    Earn 5% Cashback
  • ZO Skin Health Wrinkle + Texture Repair
    ZO Skin Health Wrinkle + Texture Repair ZO Skin Health Wrinkle + Texture Repair

    ZO Skin Health Wrinkle + Texture Repair

    Regular price
    From $130.00
    Sale price
    From $130.00
    Regular price
    Earn 5% Cashback
  • Colorescience Sunforgettable Total Protection Face Shield Classic SPF 50
    Colorescience Sunforgettable Total Protection Face Shield Classic SPF 50 Colorescience Sunforgettable Total Protection Face Shield Classic SPF 50

    Colorescience Sunforgettable Total Protection Face Shield Classic SPF 50

    Regular price
    $69.90
    Sale price
    $69.90
    Regular price
    Earn 5% Cashback
  • Vivier Refreshing Toner
    Vivier Refreshing Toner Vivier Refreshing Toner

    Vivier Refreshing Toner

    Regular price
    $58.00
    Sale price
    $58.00
    Regular price
    Earn 5% Cashback
  • Vivier Advanced Skin Lightening Serum
    Vivier Advanced Skin Lightening Serum Vivier Advanced Skin Lightening Serum

    Vivier Advanced Skin Lightening Serum

    Regular price
    $188.00
    Sale price
    $188.00
    Regular price
    Earn 5% Cashback
  • Vivier QuintiSerum™
    Vivier QuintiSerum™ Vivier QuintiSerum™

    Vivier QuintiSerum™

    Regular price
    $268.00
    Sale price
    $268.00
    Regular price
    Earn 5% Cashback
  • EltaMD UV Clear Tinted SPF 46 Broad Spectrum
    EltaMD UV Clear Tinted SPF 46 Broad Spectrum EltaMD UV Clear Tinted SPF 46 Broad Spectrum

    EltaMD UV Clear Tinted SPF 46 Broad Spectrum

    Regular price
    $84.00
    Sale price
    $84.00
    Regular price
    $84.00
    Earn 5% Cashback
  • EltaMD UV Daily Tinted Broad-Spectrum SPF 40
    EltaMD UV Daily Tinted Broad-Spectrum SPF 40 EltaMD UV Daily Tinted Broad-Spectrum SPF 40

    EltaMD UV Daily Tinted Broad-Spectrum SPF 40

    Regular price
    $78.00
    Sale price
    $78.00
    Regular price
    $78.00
    Earn 5% Cashback
  • Institut Esthederm Bronz Impulse
    Institut Esthederm Bronz Impulse Institut Esthederm Bronz Impulse

    Institut Esthederm Bronz Impulse

    Regular price
    $79.50
    Sale price
    $79.50
    Regular price
    Earn 5% Cashback
  • Esthederm Intensive Pro-Collagen+ Cream
    Esthederm Intensive Pro-Collagen+ Cream Esthederm Intensive Pro-Collagen+ Cream

    Esthederm Intensive Pro-Collagen+ Cream

    Regular price
    $109.00
    Sale price
    $109.00
    Regular price
    Earn 5% Cashback
  • Esthederm Brightening Youth Moisturizing Day Care
    Esthederm Brightening Youth Moisturizing Day Care

    Esthederm Brightening Youth Moisturizing Day Care

    Regular price
    $118.00
    Sale price
    $118.00
    Regular price
    Earn 5% Cashback
  • GM Collin Phyto Stem Cell Cream
    GM Collin Phyto Stem Cell Cream GM Collin Phyto Stem Cell Cream

    GM Collin Phyto Stem Cell Cream

    Regular price
    $160.00
    Sale price
    $160.00
    Regular price
    Earn 5% Cashback
  • GM Collin Intensive Exfoliating Gel
    GM Collin Intensive Exfoliating Gel GM Collin Intensive Exfoliating Gel

    GM Collin Intensive Exfoliating Gel

    Regular price
    $62.00
    Sale price
    $62.00
    Regular price
    Earn 5% Cashback
  • GM Collin Hydramucine Hydrating Mist
    GM Collin Hydramucine Hydrating Mist GM Collin Hydramucine Hydrating Mist

    GM Collin Hydramucine Hydrating Mist

    Regular price
    $50.00
    Sale price
    $50.00
    Regular price
    Earn 5% Cashback
  • GM Collin Puractive+ Cream
    GM Collin Puractive+ Cream GM Collin Puractive+ Cream

    GM Collin Puractive+ Cream

    Regular price
    $78.00
    Sale price
    $78.00
    Regular price
    Earn 5% Cashback
  • GM Collin Puracne Treating Gel
    GM Collin Puracne Treating Gel GM Collin Puracne Treating Gel

    GM Collin Puracne Treating Gel

    Regular price
    $80.00
    Sale price
    $80.00
    Regular price
    Earn 5% Cashback
  • GM Collin Marine Collagen Revitalizing Cream
    GM Collin Marine Collagen Revitalizing Cream GM Collin Marine Collagen Revitalizing Cream

    GM Collin Marine Collagen Revitalizing Cream

    Regular price
    $130.00
    Sale price
    $130.00
    Regular price
    Earn 5% Cashback
🏆 2026 Canadian Clinical Skincare Awards
Recognizing the most trusted, dermatologist-approved, professional-grade skincare brands leading Canada’s results-driven skin health movement.

Top 10 Medical-Grade & Professional Skincare Brands in Canada (2026)

Medical-grade skincare in Canada continues to rise sharply as dermatologists, medical spas and regulated skincare clinics emphasize professional-strength formulations with clinically validated results. Between 2024 and 2026, these brands have emerged as the most trusted, high-performing, and evidence-backed lines in the country.

This list is based on Canadian professional recommendations, clinic adoption across dermatology offices, measured client outcomes, scientific innovation and consistency in product performance. It highlights the brands most used by working professionals for pigmentation, aging, sensitivity, barrier repair, acne and preventative care.

Whether you are searching for medical-grade skincare, professional-grade skincare or dermatologist-approved skincare brands, this 2026 guide represents Canada’s most effective and results-driven product lines.

At a Glance: Canada’s Most Awarded Clinical Skincare Brands

Brand Trend Status 2026 Avg Price (CAD) Popular Age Group Hero Focus / Why It Leads
Vivier 🇨🇦
Winner: Best Clinical Vitamin C System (Canada)
Trending upward - Vitamin C category leader $$ - $$$ 30 - 60 Pharmaceutical-grade USP Vitamin C + peptides for brightening & strengthening. Shop Vivier
AlumierMD 🇨🇦/🇺🇸
Winner: Best Clean Clinical Skincare Brand
Rising - Clean, dermatologist-dispensed innovation $$ 25 - 55 Fragrance-free, dermatologist-formulated systems balancing antioxidants, exfoliants and retinoids. Shop AlumierMD
G.M. COLLIN 🇨🇦
Winner: Best Professional Spa-Clinical Hybrid Brand
Steady - Barrier repair & peptide science $$ 35 - 65 Collagen-supporting peptide systems with clinical hydration. Shop G.M. COLLIN
ZO Skin Health 🇺🇸
Winner: Best Professional Retinol Program
Leading - Aggressive correction & transformation $$$ 28 - 60 High-strength retinol and exfoliation systems for texture, tone and resilience. Shop ZO
SkinCeuticals 🇺🇸
Winner: Best Antioxidant Serum (Global)
Consistent - Antioxidant excellence $$$ 25 - 55 CE Ferulic antioxidant systems trusted worldwide.
SkinMedica 🇺🇸
Winner: Best Growth Factor Technology
Growing - Collagen & repair technology $$$ - $$$$ 35 - 65 Advanced growth factor & peptide serums. Shop SkinMedica
Obagi Medical 🇺🇸
Winner: Best Pigment-Correcting System
Classic - Protocol-based transformation $$$ 30 - 65 Retinol + pigment control systems for deep correction. Shop Obagi
Alastin Skincare 🇺🇸
Winner: Best Post-Procedure Skincare
Emerging - Collagen & recovery leader $$$ - $$$$ 35 - 65 Pre- & post-procedure collagen support.
Epionce 🇺🇸
Winner: Best Barrier Repair Brand
Niche - Dermatologist-created barrier science $$ 25 - 55 Botanical barrier-first formulations.
Revision Skincare 🇺🇸
Winner: Best Neck & Décolleté Formula
Increasing - Texture & firming expertise $$$ 40 - 70 Advanced tightening & peptide systems.

Key Clinical Skincare Trends Defining 2026

  • Multi-brand routines dominate: Canadians combine Vivier Vitamin C + ZO retinol + AlumierMD hydration.
  • Sustainable clinical packaging: Vivier and AlumierMD lead eco-conscious professional skincare.
  • Post-procedure systems expanding: SkinMedica and Alastin drive medical aftercare protocols.
  • Ingredient literacy rising: Clinics educate users on actives, improving compliance.

Choosing Brands by Age & Skin Needs

  1. Under 30: Preventative antioxidants (Vivier, AlumierMD, SkinCeuticals)
  2. 30 - 45: Brightening + retinoids (ZO, AlumierMD, G.M. Collin)
  3. 45 - 60: Growth factors + peptides (SkinMedica, Vivier, Alastin)
  4. 60+: Hydration + collagen maintenance (G.M. Collin, Revision)

Frequently Asked Questions

What defines medical-grade skincare?
Medical-grade skincare uses clinically validated actives with proven results, manufactured under pharmaceutical standards.
Which brand offers the best value?
G.M. Collin and AlumierMD offer strong daily-use performance in the 100 to 150 CAD range.
Can I combine brands in one routine?
Yes. Many Canadians pair Vivier Vitamin C with ZO retinol and SkinMedica or AlumierMD hydration to build a customized regimen.
Where can I buy authentic dermatologist-approved skincare?
You can purchase authentic, clinic-approved brands directly from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.