Canadaโ€™s Most Trusted Medical-Grade Skincare

Collection: Canadaโ€™s Most Trusted Medical-Grade Skincare

Clinically proven, dermatologist-trusted products chosen by real patients and leading Canadian skincare professionals.

โœฆ Authorized Retailer

โœฆ Free Shipping over $99

โœฆ Earn cashback on every purchase

โœฆ Free samples with every order

Canadaโ€™s Top Medical-Grade Skincare Bestsellers

Explore the most trusted clinical-strength skincare products chosen by dermatology patients, medical spas and real users across Canada. These formulations deliver consistent, measurable results for concerns including aging, pigmentation, acne, hydration and skin barrier health. Curated from our highest-performing brands such as Vivier, ZO Skin Health, AlumierMD, SkinMedica, Colorescience and more.

Showing 484 of 484 products

Sort by:
Brand
0 selected Reset
Product type
0 selected Reset
Filter and sort

Filter and sort

484 products

Brand
Product type
484 products
  • GM Collin Collagen Supreme Serum
    GM Collin Collagen Supreme Serum GM Collin Collagen Supreme Serum

    GM Collin Collagen Supreme Serum

    Regular price
    $130.00
    Sale price
    $130.00
    Regular price
    Earn 5% Cashback
  • YonKa Cleansing Gel
    YonKa Cleansing Gel YonKa Cleansing Gel

    YonKa Cleansing Gel

    Regular price
    $59.00
    Sale price
    $59.00
    Regular price
    Earn 5% Cashback
  • YonKa Lotion DS for Dry and Sensitive Skin
    YonKa Lotion DS for Dry and Sensitive Skin

    YonKa Lotion DS for Dry and Sensitive Skin

    Regular price
    $75.00
    Sale price
    $75.00
    Regular price
    Earn 5% Cashback
  • ZO Skin Health Complexion Clearing Masque
    ZO Skin Health Complexion Clearing Masque ZO Skin Health Complexion Clearing Masque

    ZO Skin Health Complexion Clearing Masque

    Regular price
    $68.00
    Sale price
    $68.00
    Regular price
    Earn 5% Cashback
  • ZO Skin Health Firming Serum
    ZO Skin Health Firming Serum ZO Skin Health Firming Serum

    ZO Skin Health Firming Serum

    Regular price
    $348.00
    Sale price
    $348.00
    Regular price
    Earn 5% Cashback
  • ZO Skin Health Aggressive Anti-Aging Program
    ZO Skin Health Aggressive Anti-Aging Program

    ZO Skin Health Aggressive Anti-Aging Program

    Regular price
    $365.00
    Sale price
    $365.00
    Regular price
    Earn 5% Cashback
  • ZO Skin Health Complexion Clearing Program
    ZO Skin Health Complexion Clearing Program
    $83.00 Off

    ZO Skin Health Complexion Clearing Program

    Regular price
    $202.00
    Sale price
    $202.00
    Regular price
    $285.00
    Earn 5% Cashback
  • Vivier V-STATโ„ข Advanced Repair Gel
    Vivier V-STATโ„ข Advanced Repair Gel Vivier V-STATโ„ข Advanced Repair Gel

    Vivier V-STATโ„ข Advanced Repair Gel

    Regular price
    $50.00
    Sale price
    $50.00
    Regular price
    Earn 5% Cashback
  • Vivier Advanced Anti-Aging Program
    Vivier Advanced Anti-Aging Program Vivier Advanced Anti-Aging Program
    $307.00 Off

    Vivier Advanced Anti-Aging Program

    Regular price
    $648.00
    Sale price
    $648.00
    Regular price
    $955.00
    Earn 5% Cashback
  • ZO Skin Health Neck Complex Anti-Aging + Brightening Serum
    ZO Skin Health Neck Complex Anti-Aging + Brightening Serum ZO Skin Health Neck Complex Anti-Aging + Brightening Serum

    ZO Skin Health Neck Complex Anti-Aging + Brightening Serum

    Regular price
    $215.00
    Sale price
    $215.00
    Regular price
    Earn 5% Cashback
  • Vivier Dark Circle Eye Cream
    Vivier Dark Circle Eye Cream Vivier Dark Circle Eye Cream

    Vivier Dark Circle Eye Cream

    Regular price
    $122.00
    Sale price
    $122.00
    Regular price
    Earn 5% Cashback
  • Omnilux Men + Neck & Dรฉcolletรฉ Bundle
    Omnilux Men + Neck & Dรฉcolletรฉ Bundle Omnilux Men + Neck & Dรฉcolletรฉ Bundle
    $165.00 Off

    Omnilux Men + Neck & Dรฉcolletรฉ Bundle

    Regular price
    $940.00
    Sale price
    $940.00
    Regular price
    $1,105.00
    Earn 5% Cashback
  • Obagi Professional-Cยฎ Serum 20%
    Obagi Professional-Cยฎ Serum 20% Obagi Professional-Cยฎ Serum 20%

    Obagi Professional-Cยฎ Serum 20%

    Regular price
    $222.00
    Sale price
    $222.00
    Regular price
    Earn 5% Cashback
  • Esthederm Absolute Smoothing Cream
    Esthederm Absolute Smoothing Cream Esthederm Absolute Smoothing Cream

    Esthederm Absolute Smoothing Cream

    Regular price
    $138.00
    Sale price
    $138.00
    Regular price
    Earn 5% Cashback
  • Esthederm Eye Contour Smoothing Care
    Esthederm Eye Contour Smoothing Care Esthederm Eye Contour Smoothing Care

    Esthederm Eye Contour Smoothing Care

    Regular price
    $99.00
    Sale price
    $99.00
    Regular price
    Earn 5% Cashback
  • Esthederm Intensive Hyaluronic Cream
    Esthederm Intensive Hyaluronic Cream Esthederm Intensive Hyaluronic Cream

    Esthederm Intensive Hyaluronic Cream

    Regular price
    $108.00
    Sale price
    $108.00
    Regular price
    Earn 5% Cashback
  • Esthederm Cellular Water Fondant Body Cream
    Esthederm Cellular Water Fondant Body Cream

    Esthederm Cellular Water Fondant Body Cream

    Regular price
    $47.00
    Sale price
    $47.00
    Regular price
    Earn 5% Cashback
  • GM Collin Ceramide Comfort Serum - 80 Capsules
    GM Collin Ceramide Comfort Serum - 80 Capsules GM Collin Ceramide Comfort Serum - 80 Capsules

    GM Collin Ceramide Comfort Serum - 80 Capsules

    Regular price
    $142.00
    Sale price
    $142.00
    Regular price
    Earn 5% Cashback
  • GM Collin Bota-Peptide Eye Contour
    GM Collin Bota-Peptide Eye Contour GM Collin Bota-Peptide Eye Contour

    GM Collin Bota-Peptide Eye Contour

    Regular price
    $95.00
    Sale price
    $95.00
    Regular price
    Earn 5% Cashback
  • Vivier Skin Brightening Cream
    Vivier Skin Brightening Cream Vivier Skin Brightening Cream

    Vivier Skin Brightening Cream

    Regular price
    $135.00
    Sale price
    $135.00
    Regular price
    Earn 5% Cashback
  • GM Collin Active Exfoliant Powder
    GM Collin Active Exfoliant Powder GM Collin Active Exfoliant Powder

    GM Collin Active Exfoliant Powder

    Regular price
    $78.00
    Sale price
    $78.00
    Regular price
    Earn 5% Cashback
  • GM Collin Sensiderm Soothing Mist
    GM Collin Sensiderm Soothing Mist GM Collin Sensiderm Soothing Mist

    GM Collin Sensiderm Soothing Mist

    Regular price
    $50.00
    Sale price
    $50.00
    Regular price
    Earn 5% Cashback
  • GM Collin Hydramucine Optimal Serum
    GM Collin Hydramucine Optimal Serum GM Collin Hydramucine Optimal Serum

    GM Collin Hydramucine Optimal Serum

    Regular price
    $90.00
    Sale price
    $90.00
    Regular price
    Earn 5% Cashback
๐Ÿ† 2026 Canadian Clinical Skincare Awards
Recognizing the most trusted, dermatologist-approved, professional-grade skincare brands leading Canadaโ€™s results-driven skin health movement.

Top 10 Medical-Grade & Professional Skincare Brands in Canada (2026)

Medical-grade skincare in Canada continues to rise sharply as dermatologists, medical spas and regulated skincare clinics emphasize professional-strength formulations with clinically validated results. Between 2024 and 2026, these brands have emerged as the most trusted, high-performing, and evidence-backed lines in the country.

This list is based on Canadian professional recommendations, clinic adoption across dermatology offices, measured client outcomes, scientific innovation and consistency in product performance. It highlights the brands most used by working professionals for pigmentation, aging, sensitivity, barrier repair, acne and preventative care.

Whether you are searching for medical-grade skincare, professional-grade skincare or dermatologist-approved skincare brands, this 2026 guide represents Canadaโ€™s most effective and results-driven product lines.

At a Glance: Canadaโ€™s Most Awarded Clinical Skincare Brands

Brand Trend Status 2026 Avg Price (CAD) Popular Age Group Hero Focus / Why It Leads
Vivier ๐Ÿ‡จ๐Ÿ‡ฆ
Winner: Best Clinical Vitamin C System (Canada)
Trending upward - Vitamin C category leader $$ - $$$ 30 - 60 Pharmaceutical-grade USP Vitamin C + peptides for brightening & strengthening. Shop Vivier
AlumierMD ๐Ÿ‡จ๐Ÿ‡ฆ/๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Clean Clinical Skincare Brand
Rising - Clean, dermatologist-dispensed innovation $$ 25 - 55 Fragrance-free, dermatologist-formulated systems balancing antioxidants, exfoliants and retinoids. Shop AlumierMD
G.M. COLLIN ๐Ÿ‡จ๐Ÿ‡ฆ
Winner: Best Professional Spa-Clinical Hybrid Brand
Steady - Barrier repair & peptide science $$ 35 - 65 Collagen-supporting peptide systems with clinical hydration. Shop G.M. COLLIN
ZO Skin Health ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Professional Retinol Program
Leading - Aggressive correction & transformation $$$ 28 - 60 High-strength retinol and exfoliation systems for texture, tone and resilience. Shop ZO
SkinCeuticals ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Antioxidant Serum (Global)
Consistent - Antioxidant excellence $$$ 25 - 55 CE Ferulic antioxidant systems trusted worldwide.
SkinMedica ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Growth Factor Technology
Growing - Collagen & repair technology $$$ - $$$$ 35 - 65 Advanced growth factor & peptide serums. Shop SkinMedica
Obagi Medical ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Pigment-Correcting System
Classic - Protocol-based transformation $$$ 30 - 65 Retinol + pigment control systems for deep correction. Shop Obagi
Alastin Skincare ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Post-Procedure Skincare
Emerging - Collagen & recovery leader $$$ - $$$$ 35 - 65 Pre- & post-procedure collagen support.
Epionce ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Barrier Repair Brand
Niche - Dermatologist-created barrier science $$ 25 - 55 Botanical barrier-first formulations.
Revision Skincare ๐Ÿ‡บ๐Ÿ‡ธ
Winner: Best Neck & Dรฉcolletรฉ Formula
Increasing - Texture & firming expertise $$$ 40 - 70 Advanced tightening & peptide systems.

Key Clinical Skincare Trends Defining 2026

  • Multi-brand routines dominate: Canadians combine Vivier Vitamin C + ZO retinol + AlumierMD hydration.
  • Sustainable clinical packaging: Vivier and AlumierMD lead eco-conscious professional skincare.
  • Post-procedure systems expanding: SkinMedica and Alastin drive medical aftercare protocols.
  • Ingredient literacy rising: Clinics educate users on actives, improving compliance.

Choosing Brands by Age & Skin Needs

  1. Under 30: Preventative antioxidants (Vivier, AlumierMD, SkinCeuticals)
  2. 30 - 45: Brightening + retinoids (ZO, AlumierMD, G.M. Collin)
  3. 45 - 60: Growth factors + peptides (SkinMedica, Vivier, Alastin)
  4. 60+: Hydration + collagen maintenance (G.M. Collin, Revision)

Frequently Asked Questions

What defines medical-grade skincare?
Medical-grade skincare uses clinically validated actives with proven results, manufactured under pharmaceutical standards.
Which brand offers the best value?
G.M. Collin and AlumierMD offer strong daily-use performance in the 100 to 150 CAD range.
Can I combine brands in one routine?
Yes. Many Canadians pair Vivier Vitamin C with ZO retinol and SkinMedica or AlumierMD hydration to build a customized regimen.
Where can I buy authentic dermatologist-approved skincare?
You can purchase authentic, clinic-approved brands directly from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.