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Best Medical-Grade Moisturizers in Canada

Moisturizer is the step that seals in hydration and reinforces the skin barrier, keeping skin resilient, smooth and protected against moisture loss. The best approach is a moisturiser matched to your skin type, a gel for oily skin or a rich cream for dry skin, applied morning and night over your serums. Shop medical-grade moisturizers from professional brands including SkinCeuticals, ZO Skin Health, AlumierMD, Vivier and GM Collin — authentic and authorized in Canada.

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  • Vivier LEXXEL® Gentle Moisturizer
    Vivier LEXXEL® Gentle Moisturizer Vivier LEXXEL® Gentle Moisturizer

    Vivier LEXXEL® Gentle Moisturizer

    Regular price
    $130.00
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    $130.00
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  • GM Collin Hydramucine Optimal Gel
    GM Collin Hydramucine Optimal Gel GM Collin Hydramucine Optimal Gel

    GM Collin Hydramucine Optimal Gel

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    $90.00
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    $90.00
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  • YonKa Elastine Day Cream
    YonKa Elastine Day Cream YonKa Elastine Day Cream

    YonKa Elastine Day Cream

    Regular price
    $115.00
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  • Alastin Ultra Nourishing Moisturizer with TriHex Technology™
    Alastin Ultra Nourishing Moisturizer with TriHex Technology™ Alastin Ultra Nourishing Moisturizer with TriHex Technology™

    Alastin Ultra Nourishing Moisturizer with TriHex Technology™

    Regular price
    $109.00
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    $109.00
    Regular price
    $109.00
    Alastin
  • ZO Skin Health Renewal Crème
    ZO Skin Health Renewal Crème ZO Skin Health Renewal Crème

    ZO Skin Health Renewal Crème

    Regular price
    $160.00
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    $160.00
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  • YonKa Hydra N.1 Creme
    YonKa Hydra N.1 Creme YonKa Hydra N.1 Creme

    YonKa Hydra N.1 Creme

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    $106.00
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    $106.00
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  • PCA Skin Collagen Hydrator
    PCA Skin Collagen Hydrator PCA Skin Collagen Hydrator
    $43.50 Off

    PCA Skin Collagen Hydrator

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    $43.50
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    $43.50
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    $87.00
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  • SkinCeuticals Phyto A+ Brightening Treatment
    SkinCeuticals Phyto A+ Brightening Treatment SkinCeuticals Phyto A+ Brightening Treatment

    SkinCeuticals Phyto A+ Brightening Treatment

    Regular price
    $155.00
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    $155.00
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    $155.00
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  • SkinCeuticals Emollience
    SkinCeuticals Emollience SkinCeuticals Emollience

    SkinCeuticals Emollience

    Regular price
    $110.00
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    $110.00
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    $110.00
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  • EltaMD AM Restore Facial Moisturizer
    EltaMD AM Restore Facial Moisturizer EltaMD AM Restore Facial Moisturizer
    $14.10 Off

    EltaMD AM Restore Facial Moisturizer

    Regular price
    $79.90
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    $79.90
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    $94.00
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  • Environ Focus Care Moisture+® Vita-Complex Super Moisturiser
    Environ Focus Care Moisture+®  Vita-Complex Super Moisturiser Environ Focus Care Moisture+®  Vita-Complex Super Moisturiser

    Environ Focus Care Moisture+® Vita-Complex Super Moisturiser

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    $70.00
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    $70.00
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    $70.00
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  • GM Collin Phyto Stem Cell Cream
    GM Collin Phyto Stem Cell Cream GM Collin Phyto Stem Cell Cream

    GM Collin Phyto Stem Cell Cream

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    $160.00
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    $160.00
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  • PCA Skin Clearskin
    PCA Skin Clearskin PCA Skin Clearskin
    $44.50 Off

    PCA Skin Clearskin

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    $44.51
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    $44.51
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    $89.01
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  • SkinMedica Rejuvenative Moisturizer
    SkinMedica Rejuvenative Moisturizer SkinMedica Rejuvenative Moisturizer

    SkinMedica Rejuvenative Moisturizer

    Regular price
    $79.00
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    $79.00
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  • GM Collin CC Cream
    GM Collin CC Cream GM Collin CC Cream

    GM Collin CC Cream

    Regular price
    $60.00
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    $60.00
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  • EltaMD PM Restore Moisturizer (1.7oz)
    EltaMD PM Restore Moisturizer (1.7oz) EltaMD PM Restore Moisturizer (1.7oz)
    $13.50 Off

    EltaMD PM Restore Moisturizer (1.7oz)

    Regular price
    $76.50
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    $76.50
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    $90.00
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  • Neocutis Bio Cream Firm Riche
    Neocutis Bio Cream Firm Riche Neocutis Bio Cream Firm Riche

    Neocutis Bio Cream Firm Riche

    Regular price
    $180.00
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    $180.00
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    Advanced Regenerative Skincare
  • PCA Skin ReBalance
    PCA Skin ReBalance PCA Skin ReBalance
    $43.50 Off

    PCA Skin ReBalance

    Regular price
    $43.50
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    $43.50
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    $87.00
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  • YonKa Phyto 52
    YonKa Phyto 52 YonKa Phyto 52

    YonKa Phyto 52

    Regular price
    $115.00
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    $115.00
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  • Vivier Radiant Eye Contour Cream
    Vivier Radiant Eye Contour Cream Vivier Radiant Eye Contour Cream

    Vivier Radiant Eye Contour Cream

    Regular price
    $126.00
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    $126.00
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    $126.00
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  • SkinCeuticals Epidermal Repair
    SkinCeuticals Epidermal Repair SkinCeuticals Epidermal Repair

    SkinCeuticals Epidermal Repair

    Regular price
    $105.00
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    $105.00
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    $105.00
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  • Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1
    Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1 Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1

    Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1

    Regular price
    $100.00
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    $100.00
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    $100.00
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  • YonKa Hydra N.1 Fluide
    YonKa Hydra N.1 Fluide YonKa Hydra N.1 Fluide

    YonKa Hydra N.1 Fluide

    Regular price
    $106.00
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    $106.00
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The Complete Guide to Moisturizers

The right moisturizer locks in hydration, strengthens the skin barrier and keeps active ingredients working, making it essential for every skin type, even oily skin. WeDoSkin carries medical-grade moisturizers from the professional brands trusted in Canadian clinics.

Browse best-selling moisturizers below with live Canadian pricing, from lightweight gels to barrier-repairing creams.

💧

Barrier Repair

Ceramides, lipids and humectants reinforce a healthy moisture barrier.

🪶

Gel to Rich

Textures for every skin type, from oil-free gels to nourishing creams.

🔒

Locks In Actives

Seals serums beneath to keep treatments hydrated and effective.

🇨🇦

Authorized & Authentic

Fresh, correctly stored, sourced directly from the manufacturer.

The Science Behind Moisturizers

How Moisturizers's key actives work — and why formulation and delivery matter as much as the ingredient itself.

Humectants

Draw Water In

Hyaluronic acid and glycerin pull moisture into the skin's upper layers.

Emollients

Smooth & Soften

Lipids and oils fill gaps between skin cells for a smooth, supple feel.

Occlusives

Seal It In

Barrier-forming ingredients reduce water loss, crucial for dry and compromised skin.

These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Moisturizers Bestsellers

The most-loved Moisturizers products at WeDoSkin. Tap any product to shop.

Shop the Full Moisturizers Range

Browse every Moisturizers product by category, with live Canadian pricing.

How to Choose What's Right for You

New to Moisturizers? Start with your primary concern — here's where most people begin.

Moisturizers: Frequently Asked Questions

Do oily skin types need moisturizer?

Yes. Even oily skin needs hydration; skipping moisturizer can trigger more oil production. Choose a lightweight, oil-free gel moisturizer that hydrates without heaviness.

What is the best moisturizer for dry skin?

Dry skin benefits from rich creams with ceramides, lipids and occlusives, such as SkinCeuticals Triple Lipid Restore or ZO Hydrating Creme, applied to slightly damp skin to seal in moisture.

When should I apply moisturizer?

Apply moisturizer morning and night as one of the last steps, after serums and before sunscreen in the morning. It seals in your treatments and hydration.

What is the difference between a serum and a moisturizer?

Serums deliver concentrated actives into the skin; moisturizers hydrate and seal the barrier. They work best together, serum first, then moisturizer to lock it in.

Can a moisturizer repair my skin barrier?

Barrier-repair moisturizers with ceramides, niacinamide and fatty acids help restore a compromised barrier, reducing dryness, sensitivity and the effects of over-exfoliation.

How much moisturizer should I use?

A pea-to-almond-sized amount is usually enough for the face and neck. Apply to slightly damp skin to maximise hydration.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

Moisturizer guidance here reflects standard dermatological principles on hydration and barrier health. As a Preferred Authorized Retailer, WeDoSkin stores and ships every formula correctly so it performs as intended. This is educational and not a substitute for personalized medical advice.

Last reviewed March 18, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

Explore Related Concerns & Ingredients

The concern and ingredient hubs Moisturizers products most often appear in at WeDoSkin.

Why Canadians Choose WeDoSkin

Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.

Authorized & AuthenticEvery product is sourced directly from the brand — never grey-market — with full manufacturer warranty.
100,000+ Happy CustomersA trusted Canadian destination for medical-grade skincare, with thousands of verified reviews on Trustpilot, Google and Judge.me.
Rewards That Never ExpireEarn 5–20% cashback with no dated points and no minimum to redeem — more rewarding than typical points programs.
100-Day ReturnsReturn unopened products for a full 100 days, or opened products for 45 days through BuySure.
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45+ Brands, 3,000+ ProductsFrom ZO Skin Health and SkinCeuticals to Vivier, AlumierMD and dozens more — plus complimentary clinical guidance.

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Questions about Moisturizers?

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