✓ Authorized ZO retailer - Ships in 2-4 business days

ZO Skin Health Radical Night Repair

Regular price
$240.00
Sale price
$240.00
Regular price
Earn 5% Cashback

Radical Night Repair, formulated with 1% retinol, enhances skin texture, evens pigmentation, and reduces fine lines and wrinkles. Be sure to read the usage directions and anticipated reactions before use.

  • ENJOY FREE SHIPPING $65+
  • PROTECTED & SECURE DELIVERY
  • FREE SAMPLES WITH EVERY ORDER
  • Description

  • Key Benefits

  • How to use

  • Ingredients

  • Frequently Asked Questions

Description

ZO Skin Health Radical Night Repair is an intensive overnight treatment formulated with 1% encapsulated retinol to dramatically improve the appearance of aging and photo-damaged skin. It supports skin renewal by boosting collagen production, reducing the look of deep wrinkles, and refining rough texture and uneven tone.

This high-strength formula is clinically proven to stimulate cellular turnover, promote firmness, and restore skin smoothness. Radical Night Repair is ideal for experienced retinol users seeking visible transformation in skin clarity, firmness, and radiance. Due to its potency, a gradual introduction and physician guidance are recommended.

Ideal for advanced aging concerns, sun damage, and uneven texture

Size: 60 mL / 2 Fl Oz.

ZO Radical Night Repair FAQs

How strong is Radical Night Repair?
It contains 1% encapsulated retinol — ZO's highest everyday retinol strength — so it is best for experienced retinol users.

How should I introduce it?
Start 2–3 nights a week and build up gradually as tolerated. Always wear a broad-spectrum SPF the next day.

New to retinol?
Begin with the ZO Retinol Skin Brightener 0.25% or 0.5% and work up before moving to a 1% formula.

Key Benefits

How to use

Ingredients

Frequently Asked Questions

Recommended Products

You might also like these

Free Shipping

Get free Canada wide shipping for orders over $65.

Guarantee

Our products are 100% genuine, we only sell products we truly believe in.

Earn Cashback

Get rewarded and redeem your cashback toward future purchases.

Order Protection

Shop with confidence with our 45-Day Satisfaction Guarantee*

  • Preferred Authorized Retailer
  • 100,000+ Happy Customers
  • Earn 5% Cashback
  • 100-Day Returns*
  • Free Samples

ZO Radical Night Repair: 1% Encapsulated Retinol for Visible Overnight Renewal

ZO Skin Health Radical Night Repair is an intensive overnight treatment built around 1% encapsulated retinol to refine deep wrinkles, rough texture, and uneven tone on photo-damaged, aging skin.

The encapsulated delivery releases retinol steadily through the night to support collagen and cellular turnover with less of the harshness high-strength retinol can cause. WeDoSkin.ca is a Preferred Authorized Retailer for ZO Skin Health in Canada, with authentic, fresh stock.

🌙

1% Encapsulated Retinol

High-strength retinol released steadily overnight for visible renewal.

💪

Collagen & Firmness

Supports collagen and turnover to firm and smooth the skin.

🪞

Texture & Tone

Refines rough texture and helps even out uneven tone over time.

🔒

Encapsulated Delivery

Buffers potency for results with less of retinol's typical harshness.

Key Ingredients & How They Work

The actives that drive Radical Night Repair — and what each one does for your skin.

RETINOL 1%

High-Strength Renewal

A potent retinol concentration clinically associated with visible anti-aging change.

ENCAPSULATION

Steady Release

Microencapsulation releases retinol gradually to support tolerance.

COLLAGEN

Firmness Support

Boosts cellular turnover that underpins firmer, smoother skin.

NIGHTLY

Overnight Repair

Works while you sleep, when skin is primed for renewal.

These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Benefits of Radical Night Repair

Softens the look of deep wrinkles and fine lines
Refines rough, uneven texture
Helps even tone and improve clarity
Supports collagen and firmness
Encapsulated for steadier, more comfortable results
Intensive 60 ml overnight treatment

What Radical Night Repair Pairs Well With

Build a complete routine — these pairings are most often recommended alongside Radical Night Repair. Tap any product to shop.

How to Use

  1. Introduce gradually — start two to three nights per week and build up as tolerated.
  2. Apply a small amount to clean, dry skin at night, avoiding the immediate eye area.
  3. Always pair with daily broad-spectrum SPF; retinol increases sun sensitivity.

Who It's For

  • Experienced retinol users seeking visible transformation
  • Advanced aging, deep wrinkles, and photo-damage
  • Rough texture and uneven tone
  • Those wanting high-strength renewal with steadier delivery

Sensitivity note: This is a high-strength retinol. Build up slowly, expect a possible adjustment period, and use under professional guidance. Not recommended during pregnancy or breastfeeding.

How Radical Night Repair Compares

Where Radical Night Repair sits relative to other options. The right fit depends on your skin and goals.

Radical Night Repair vs the Alternatives
FeatureZO Radical Night RepairStandard Retinol BrightenersRetinol Creams
Retinol strength1% encapsulated — high strengthLower to moderate strengthOften low strength
DeliveryEncapsulated, steady overnight releaseVariesVaries
TargetDeep wrinkles, advanced agingTone and early linesGeneral maintenance
User levelExperienced retinol usersBeginner to intermediateBeginner

Radical Night Repair: Frequently Asked Questions

Who is Radical Night Repair for?

It is designed for experienced retinol users targeting advanced aging — deep wrinkles, rough texture, and photo-damage — who want high-strength overnight renewal.

How often should I use it?

Start two to three nights a week and gradually build up as your skin adjusts. Its 1% encapsulated retinol is potent, so easing in helps minimise irritation.

Why encapsulated retinol?

Encapsulation releases the retinol steadily through the night, which helps deliver strong results with less of the dryness and flaking high-strength retinol can cause.

Do I need sunscreen with it?

Yes, always. Retinol increases sun sensitivity, so daily broad-spectrum SPF is essential to protect your skin and your results.

Can beginners use it?

It is best for those already comfortable with retinol. If you are new, start with a lower-strength ZO retinol and work up to this one.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.

Last reviewed March 18, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

Explore Related Concerns & Ingredients

The concern and ingredient hubs Radical Night Repair most often appears in at WeDoSkin.

Why Canadians Choose WeDoSkin

Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.

Authorized & AuthenticEvery product is sourced directly from the brand — never grey-market — with full manufacturer warranty.
100,000+ Happy CustomersA trusted Canadian destination for medical-grade skincare, with thousands of verified reviews on Trustpilot, Google and Judge.me.
Rewards That Never ExpireEarn 5–20% cashback with no dated points and no minimum to redeem — more rewarding than typical points programs.
100-Day ReturnsReturn unopened products for a full 100 days, or opened products for 45 days through BuySure.
Free Shipping Over $65Fast, Canada-wide delivery, with complimentary samples included in every order.
45+ Brands, 3,000+ ProductsFrom ZO Skin Health and SkinCeuticals to Vivier, AlumierMD and dozens more — plus complimentary clinical guidance.

Why shop with WeDoSkin →

Questions about Radical Night Repair?

Connect with a WeDoSkin clinical expert for a complimentary consultation.

Contact Our Skincare Experts