Best Antioxidant Serums for Skin in Canada
Antioxidants neutralise the free radicals — from UV and pollution — that break down collagen and accelerate visible aging. The most effective way to use them is in a morning serum (vitamin C, vitamin E, ferulic acid, resveratrol) layered under SPF for compounding daytime defence. Shop medical-grade antioxidant skincare from professional brands including SkinCeuticals, ZO Skin Health, Vivier, iS Clinical and AlumierMD — authentic and authorized in Canada.
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ZO Skin Health Retinol Skin Brightener 0.5%All Products
ZO Skin Health Retinol Skin Brightener 0.5%
- Regular price
- $165.00
- Sale price
- $165.00
- Regular price
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Alastin Restorative Skin Complex with TriHex Technology™Advanced Regenerative Skincare
Alastin Restorative Skin Complex with TriHex Technology™
- Regular price
- $273.96
- Sale price
- $273.96
- Regular price
- $199.97
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TiZO® AM Replenish SPF 40 Non-TintedAll Products
TiZO® AM Replenish SPF 40 Non-Tinted
- Regular price
- $84.00
- Sale price
- $84.00
- Regular price
- $84.00
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TiZO Photoceutical PM RestoreAll Products
TiZO Photoceutical PM Restore
- Regular price
- $106.00
- Sale price
- $106.00
- Regular price
- $106.00
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Colorescience Pep Up Collagen Boost Face & Neck SerumAll Products
Colorescience Pep Up Collagen Boost Face & Neck Serum
- Regular price
- $229.90
- Sale price
- $229.90
- Regular price
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SkinCeuticals Resveratrol B EAll Products
SkinCeuticals Resveratrol B E
- Regular price
- $230.00
- Sale price
- $230.00
- Regular price
- $230.00
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SkinBetter Techno Neck Perfecting CreamAll Products
SkinBetter Techno Neck Perfecting Cream
- Regular price
- $250.00
- Sale price
- $250.00
- Regular price
- $250.00
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Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1All Products
Environ Skin EssentiA® Vita-Antioxidant AVST Moisturiser 1
- Regular price
- $100.00
- Sale price
- $100.00
- Regular price
- $100.00
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YonKa Nutri+ BoosterAll Products
YonKa Nutri+ Booster
- Regular price
- $88.00
- Sale price
- $88.00
- Regular price
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FOREO Call It a Night UFO™ Activated MaskAll Products
FOREO Call It a Night UFO™ Activated Mask
- Regular price
- $18.00
- Sale price
- $18.00
- Regular price
- $18.00
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Blemish Control BarAll Products
Blemish Control Bar
- Regular price
- $44.50
- Sale price
- $44.50
- Regular price
- $89.00
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GlyMed Daily Skin ClarifierAll Products
GlyMed Daily Skin Clarifier
- Regular price
- $69.50
- Sale price
- $69.50
- Regular price
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SkinCeuticals AOX+ Eye GelAll Products
SkinCeuticals AOX+ Eye Gel
- Regular price
- $135.00
- Sale price
- $135.00
- Regular price
- $135.00
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Obagi CLENZIderm M.D.® Pore TherapyAll Products
Obagi CLENZIderm M.D.® Pore Therapy
- Regular price
- $73.00
- Sale price
- $73.00
- Regular price
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iS Clinical Pure Calm CollectionAll Products
iS Clinical Pure Calm Collection
- Regular price
- $280.00
- Sale price
- $280.00
- Regular price
- $280.00
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iS Clinical Youth SerumAll Products
iS Clinical Youth Serum
- Regular price
- $229.00
- Sale price
- $229.00
- Regular price
- $245.00
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NuFACE Prep-N-Glow® Dual-Sided Cloths (5 pack)Accessories
NuFACE Prep-N-Glow® Dual-Sided Cloths (5 pack)
- Regular price
- $16.00
- Sale price
- $16.00
- Regular price
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FOREO Bulgarian Rose Sheet Mask (3x)All Products
FOREO Bulgarian Rose Sheet Mask (3x)
- Regular price
- $26.03
- Sale price
- $26.03
- Regular price
- $19.00
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Vivier Kine-CAll Products
Vivier Kine-C
- Regular price
- $198.00
- Sale price
- $198.00
- Regular price
- $198.00
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Vivier GrenzCine® FaceAll Products
Vivier GrenzCine® Face
- Regular price
- $292.00
- Sale price
- $292.00
- Regular price
- $292.00
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iS Clinical Brightening SerumAll Products
iS Clinical Brightening Serum
- Regular price
- $200.00
- Sale price
- $200.00
- Regular price
- $200.00
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iS Clinical Tri-Active Exfoliant MasqueAll Products
iS Clinical Tri-Active Exfoliant Masque
- Regular price
- $137.00
- Sale price
- $137.00
- Regular price
- $137.00
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iS Clinical Hydra-Intensive Cooling MasqueAll Products
iS Clinical Hydra-Intensive Cooling Masque
- Regular price
- $137.00
- Sale price
- $137.00
- Regular price
- $137.00
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The Complete Guide to Antioxidants
Antioxidants are your skin's daily defense against the free radicals from UV and pollution that drive premature ageing, dullness and dark spots. This guide covers the best antioxidant serums in Canada — from the classic vitamin C + E + ferulic trio to resveratrol and peptide-powered formulas.
Every antioxidant serum below is 100% authentic and shipped fast across Canada from WeDoSkin, a Preferred Authorized Retailer, with free samples and 5% cashback on every order.
Neutralise Free Radicals
Antioxidants disarm the free radicals from UV and pollution that drive premature ageing.
Boost Your SPF
Worn in the morning under sunscreen, antioxidants add a second layer of daytime defense.
Brighten & Even
Many antioxidants also fade dullness and even out tone for visible radiance.
Calm & Protect
Polyphenol antioxidants help soothe and protect stressed, reactive skin.
The Science Behind Antioxidants
How Antioxidants's key actives work — and why formulation and delivery matter as much as the ingredient itself.
Vitamin C
The hero antioxidant — it brightens, supports collagen and neutralises free radicals. Most potent when fresh and formulated at a low pH.
Vitamin E & Ferulic Acid
Lipid-soluble vitamin E and ferulic acid stabilise vitamin C and extend daytime protection — the classic C + E + ferulic trio.
Resveratrol & Polyphenols
Plant polyphenols like resveratrol and green tea add night-time antioxidant defense and help calm the skin.
Peptides & Niacinamide
Niacinamide and peptides round out antioxidant formulas, strengthening the barrier while defending against environmental stress.
These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Antioxidants Bestsellers
The most-loved Antioxidants products at WeDoSkin. Tap any product to shop.
Alumier EverActive C&E™ + Peptide (3 Pack)$230.00Shop now →
SkinCeuticals C E Ferulic$230.00Shop now →
Alumier Alumience A.G.E.™$176.00Shop now →
Alumier EverActive C&E + Peptide Single$100.50Shop now →
Alumier EvenTone$140.00Shop now →
Alumier Calm-R®$158.00Shop now →
Alumier HydraDew$88.50Shop now →
Alumier Recovery Balm$111.00Shop now →Shop the Full Antioxidants Range
Browse every Antioxidants product by category, with live Canadian pricing.
How to Choose What's Right for You
New to Antioxidants? Start with your primary concern — here's where most people begin.
Best Overall Antioxidant Serums
Best for Brightening
Best for Sensitive & Redness
Best for Anti-Aging Night Defense
Antioxidants: Frequently Asked Questions
What is the best antioxidant serum in Canada?
Top antioxidant serums include AlumierMD EverActive C&E + Peptide, SkinCeuticals C E Ferulic and Alumience A.G.E. The best one depends on whether you want fresh-activated vitamin C, a ready-to-use C+E+ferulic formula or a multi-antioxidant night serum.
What do antioxidants do for your skin?
Antioxidants neutralise free radicals generated by UV light and pollution. Left unchecked, those free radicals damage collagen and accelerate visible ageing, so a daily antioxidant helps protect against fine lines, dullness and dark spots.
Antioxidant serum vs vitamin C serum — what's the difference?
Vitamin C is the most popular antioxidant, so most vitamin C serums are antioxidant serums. But antioxidants also include vitamin E, ferulic acid, resveratrol and green tea — many of the best formulas combine several for broader protection.
When should I apply antioxidant serum, morning or night?
Morning is ideal, since antioxidants boost your daytime defense and work synergistically under sunscreen. Some polyphenol antioxidants like resveratrol are designed for night-time repair, so a few people use one of each.
What is the best antioxidant for anti-aging?
A well-formulated vitamin C + E + ferulic serum such as C E Ferulic or EverActive C&E + Peptide is the gold standard for anti-aging defense, ideally paired with retinol at night and daily SPF.
Can I use antioxidants with retinol?
Yes — most people use an antioxidant in the morning and retinol at night. This keeps each ingredient working at its best and minimises irritation.
Do antioxidants replace sunscreen?
No. Antioxidants complement sunscreen but don't replace it — think of them as a second layer of defense under your SPF. Always finish your morning routine with a broad-spectrum sunscreen.
What are the best antioxidants for sensitive skin?
Gentler antioxidant options like Calm-R, polyphenol-based formulas and barrier-supporting moisturisers tend to suit sensitive skin best. Introduce a potent vitamin C slowly if your skin is reactive.
Which antioxidants work best together?
Vitamin C, vitamin E and ferulic acid are a classic, well-studied combination — vitamin E and ferulic acid stabilise the vitamin C and extend its protective benefits.
How long do antioxidant serums take to work?
Antioxidant protection starts immediately, while visible brightening and a more even, radiant tone typically build over 4-12 weeks of consistent daily use.
Where can I buy authentic antioxidant skincare in Canada?
WeDoSkin is a Preferred Authorized Canadian Retailer for AlumierMD, SkinCeuticals, ZO Skin Health and more, so every antioxidant serum is authentic, fresh and shipped fast Canada-wide.
This antioxidant guide is maintained and reviewed by the WeDoSkin Clinical Team. As a Preferred Authorized Canadian Retailer we handle these formulas every day and only list authentic, in-date stock. Information here is educational and not a substitute for personalized medical advice.
Explore Related Concerns & Ingredients
The concern and ingredient hubs Antioxidants products most often appear in at WeDoSkin.
Why Canadians Choose WeDoSkin
Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.
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