Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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498 products
  • PCA Skin Daily Cleansing Oil
    PCA Skin Daily Cleansing Oil PCA Skin Daily Cleansing Oil

    PCA Skin Daily Cleansing Oil

    Regular price
    $78.00
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    $78.00
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    $78.00
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  • ZO Skin Health Intense Eye Crème
    ZO Skin Health Intense Eye Crème ZO Skin Health Intense Eye Crème

    ZO Skin Health Intense Eye Crème

    Regular price
    $170.00
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    $170.00
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  • PCA Skin HydraLuxe 1.8 oz
    PCA Skin HydraLuxe 1.8 oz PCA Skin HydraLuxe 1.8 oz

    PCA Skin HydraLuxe 1.8 oz

    Regular price
    $230.00
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    $230.00
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    $230.00
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  • SkinBetter AlphaRet Overnight Cream
    SkinBetter AlphaRet Overnight Cream SkinBetter AlphaRet Overnight Cream

    SkinBetter AlphaRet Overnight Cream

    Regular price
    $210.00
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    $210.00
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  • SkinMedica TNS Eye Repair
    SkinMedica TNS Eye Repair SkinMedica TNS Eye Repair

    SkinMedica TNS Eye Repair

    Regular price
    $108.00
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    $108.00
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  • SkinMedica TNS Advanced+ Serum
    SkinMedica TNS Advanced+ Serum SkinMedica TNS Advanced+ Serum

    SkinMedica TNS Advanced+ Serum

    Regular price
    $330.00
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    $330.00
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  • ZO Skin Health Neck Complex Anti-Aging + Brightening Serum
    ZO Skin Health Neck Complex Anti-Aging + Brightening Serum ZO Skin Health Neck Complex Anti-Aging + Brightening Serum

    ZO Skin Health Neck Complex Anti-Aging + Brightening Serum

    Regular price
    $215.00
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    $215.00
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  • Obagi360®Retinol 1.0
    Obagi360®Retinol 1.0 Obagi360®Retinol 1.0

    Obagi360®Retinol 1.0

    Regular price
    $126.00
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    $126.00
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  • Obagi Professional-C® Serum 20%
    Obagi Professional-C® Serum 20% Obagi Professional-C® Serum 20%

    Obagi Professional-C® Serum 20%

    Regular price
    $222.00
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    $222.00
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  • Obagi CLENZIderm M.D.® Therapeutic Moisturizer
    Obagi CLENZIderm M.D.® Therapeutic Moisturizer Obagi CLENZIderm M.D.® Therapeutic Moisturizer

    Obagi CLENZIderm M.D.® Therapeutic Moisturizer

    Regular price
    $74.00
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    $74.00
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  • Neocutis Lumière Firm Eye Cream
    Neocutis Lumière Firm Eye Cream Neocutis Lumière Firm Eye Cream

    Neocutis Lumière Firm Eye Cream

    Regular price
    $100.00
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    $100.00
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  • Neocutis Neo Firm
    Neocutis Neo Firm Neocutis Neo Firm

    Neocutis Neo Firm

    Regular price
    $160.00
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    $160.00
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  • Environ Focus Care Moisture+® Vita-Complex Super Moisturiser
    Environ Focus Care Moisture+®  Vita-Complex Super Moisturiser Environ Focus Care Moisture+®  Vita-Complex Super Moisturiser

    Environ Focus Care Moisture+® Vita-Complex Super Moisturiser

    Regular price
    $70.00
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    $70.00
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    $70.00
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  • Environ Focus Care Youth+® Tri BioBotanical Revival Masque
    Environ Focus Care Youth+® Tri BioBotanical Revival Masque Environ Focus Care Youth+® Tri BioBotanical Revival Masque

    Environ Focus Care Youth+® Tri BioBotanical Revival Masque

    Regular price
    $110.00
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    $110.00
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    $110.00
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  • Esthederm Age Proteom™ Advanced Serum
    Esthederm Age Proteom™ Advanced Serum Esthederm Age Proteom™ Advanced Serum

    Esthederm Age Proteom™ Advanced Serum

    Regular price
    $139.00
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    $139.00
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  • Esthederm Intensive Vitamine C Gel-Cream
    Esthederm Intensive Vitamine C Gel-Cream Esthederm Intensive Vitamine C Gel-Cream

    Esthederm Intensive Vitamine C Gel-Cream

    Regular price
    $110.00
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    $110.00
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  • Yonka Excellence Code Ritual - Holiday Edition
    Yonka Excellence Code Ritual - Holiday Edition

    Yonka Excellence Code Ritual - Holiday Edition

    Regular price
    $330.00
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    $330.00
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    $330.00
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  • YonKa For Men Ritual - Holiday Set
    YonKa For Men Ritual - Holiday Set

    YonKa For Men Ritual - Holiday Set

    Regular price
    $140.00
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    $140.00
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    $140.00
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  • GM Collin Diamond Gift Set - Holiday Edition
    GM Collin Diamond Gift Set - Holiday Edition

    GM Collin Diamond Gift Set - Holiday Edition

    Regular price
    $580.00
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    $580.00
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    $580.00
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  • GMC Medical GF Advanced Serum
    GMC Medical GF Advanced Serum

    GMC Medical GF Advanced Serum

    Regular price
    $200.00
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    $200.00
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  • GMC Medical A.G.E. Eye Repair Cream
    GMC Medical A.G.E. Eye Repair Cream

    GMC Medical A.G.E. Eye Repair Cream

    Regular price
    $110.00
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    $110.00
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  • Alumier Prep & Enhance Discolouration (Non-HQ)
    Alumier Prep & Enhance Discolouration (Non-HQ) Alumier Prep & Enhance Discolouration (Non-HQ)
    8% off

    Alumier Prep & Enhance Discolouration (Non-HQ)

    Regular price
    $365.00
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    $365.00
    Regular price
    $395.00
    Earn 5% Cashback
  • BABOR The Cure Cream
    BABOR The Cure Cream BABOR The Cure Cream

    BABOR The Cure Cream

    Regular price
    $185.00
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    $185.00
    Regular price
    $185.00
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Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.