Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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  • ZO Skin Health Anti-Aging Program
    ZO Skin Health Anti-Aging Program ZO Skin Health Anti-Aging Program
    24% off

    ZO Skin Health Anti-Aging Program

    Regular price
    $300.00
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    $300.00
    Regular price
    $395.00
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  • PCA Skin C&E Advanced with Hexylresorcinol
    PCA Skin C&E Advanced with Hexylresorcinol PCA Skin C&E Advanced with Hexylresorcinol
    24% off

    PCA Skin C&E Advanced with Hexylresorcinol

    Regular price
    $145.00
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    $145.00
    Regular price
    $192.00
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  • Vivier Advanced Anti-Aging Program
    Vivier Advanced Anti-Aging Program Vivier Advanced Anti-Aging Program
    32% off

    Vivier Advanced Anti-Aging Program

    Regular price
    $648.00
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    $648.00
    Regular price
    $955.00
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  • Vivier Dark Circle Eye Cream
    Vivier Dark Circle Eye Cream Vivier Dark Circle Eye Cream

    Vivier Dark Circle Eye Cream

    Regular price
    $122.00
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    $122.00
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  • Esthederm Age Proteom Eye Advanced Serum
    Esthederm Age Proteom Eye Advanced Serum Esthederm Age Proteom Eye Advanced Serum

    Esthederm Age Proteom Eye Advanced Serum

    Regular price
    $109.00
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    $109.00
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  • Esthederm Intensive Hyaluronic Cream
    Esthederm Intensive Hyaluronic Cream Esthederm Intensive Hyaluronic Cream

    Esthederm Intensive Hyaluronic Cream

    Regular price
    $108.00
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    $108.00
    Regular price
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  • GMC Medical A.G.E. Skin Defence
    GMC Medical A.G.E. Skin Defence

    GMC Medical A.G.E. Skin Defence

    Regular price
    $155.00
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    $155.00
    Regular price
    $155.00
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  • GM Collin Bota-Peptides Cream
    GM Collin Bota-Peptides Cream GM Collin Bota-Peptides Cream

    GM Collin Bota-Peptides Cream

    Regular price
    $136.00
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    $136.00
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  • GM Collin Ceramide Comfort Serum - 40 Capsules
    GM Collin Ceramide Comfort Serum - 40 Capsules GM Collin Ceramide Comfort Serum - 40 Capsules

    GM Collin Ceramide Comfort Serum - 40 Capsules

    Regular price
    $136.00
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    $136.00
    Regular price
    $136.00
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  • PCA Skin C&E Strength Max
    PCA Skin C&E Strength Max PCA Skin C&E Strength Max

    PCA Skin C&E Strength Max

    Regular price
    $177.00
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    $177.00
    Regular price
    $177.00
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  • Colorescience Total Eye® Firm & Repair Cream
    Colorescience Total Eye® Firm & Repair Cream Colorescience Total Eye® Firm & Repair Cream

    Colorescience Total Eye® Firm & Repair Cream

    Regular price
    $129.90
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    $129.90
    Regular price
    $129.90
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  • EltaMD PM Restore Moisturizer (1.7oz)
    EltaMD PM Restore Moisturizer (1.7oz) EltaMD PM Restore Moisturizer (1.7oz)

    EltaMD PM Restore Moisturizer (1.7oz)

    Regular price
    $90.00
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    $90.00
    Regular price
    $90.00
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  • GM Collin Hydramucine Optimal Serum
    GM Collin Hydramucine Optimal Serum GM Collin Hydramucine Optimal Serum

    GM Collin Hydramucine Optimal Serum

    Regular price
    $86.00
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    $86.00
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  • GM Collin Retinol Advanced + Night Cream
    GM Collin Retinol Advanced + Night Cream GM Collin Retinol Advanced + Night Cream

    GM Collin Retinol Advanced + Night Cream

    Regular price
    $116.00
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    $116.00
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  • YonKa Nutri Defense Cream (Dry Skin)
    YonKa Nutri Defense Cream (Dry Skin) YonKa Nutri Defense Cream (Dry Skin)

    YonKa Nutri Defense Cream (Dry Skin)

    Regular price
    $100.00
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    $100.00
    Regular price
    $100.00
    Earn 5% Cashback
  • Vivier Skin Brightening Cream
    Vivier Skin Brightening Cream Vivier Skin Brightening Cream

    Vivier Skin Brightening Cream

    Regular price
    $135.00
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    $135.00
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  • GM Collin Hyaluronic Filler Serum
    GM Collin Hyaluronic Filler Serum GM Collin Hyaluronic Filler Serum

    GM Collin Hyaluronic Filler Serum

    Regular price
    $130.00
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    $130.00
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  • YonKa Nutri+ Booster
    YonKa Nutri+ Booster YonKa Nutri+ Booster

    YonKa Nutri+ Booster

    Regular price
    $88.00
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    $88.00
    Regular price
    $88.00
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  • YonKa Advanced Optimizer Serum
    YonKa Advanced Optimizer Serum YonKa Advanced Optimizer Serum

    YonKa Advanced Optimizer Serum

    Regular price
    $142.00
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    $142.00
    Regular price
    $142.00
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  • YonKa Serum C20
    YonKa Serum C20 YonKa Serum C20

    YonKa Serum C20

    Regular price
    $194.00
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    $194.00
    Regular price
    $194.00
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  • NuFACE Hydrating Aqua Gel Activator (50ml)
    NuFACE Hydrating Aqua Gel Activator (50ml) NuFACE Hydrating Aqua Gel Activator (50ml)

    NuFACE Hydrating Aqua Gel Activator (50ml)

    Regular price
    $50.00
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    $50.00
    Regular price
    $50.00
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  • Advanced Nutrition Programme Skin Omegas+ (60 Capsules)
    Advanced Nutrition Programme Skin Omegas+ (60 Capsules) Advanced Nutrition Programme Skin Omegas+ (60 Capsules)
    13% off

    Advanced Nutrition Programme Skin Omegas+ (60 Capsules)

    Regular price
    $56.00
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    $56.00
    Regular price
    $64.00
    Earn 5% Cashback
  • Advanced Nutrition Programme Skin Complete (120 capsules)
    Advanced Nutrition Programme Skin Complete (120 capsules) Advanced Nutrition Programme Skin Complete (120 capsules)
    13% off

    Advanced Nutrition Programme Skin Complete (120 capsules)

    Regular price
    $89.00
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    $89.00
    Regular price
    $102.00
    Earn 5% Cashback

Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.