Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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536 products
  • PCA Skin Nutrient Toner
    PCA Skin Nutrient Toner PCA Skin Nutrient Toner

    PCA Skin Nutrient Toner

    Regular price
    $68.00
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    $68.00
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    $68.00
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  • Vivier QuintiSerum™
    Vivier QuintiSerum™ Vivier QuintiSerum™

    Vivier QuintiSerum™

    Regular price
    $268.00
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    $268.00
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  • PCA Skin Retinol Treatment for Sensitive Skin
    PCA Skin Retinol Treatment for Sensitive Skin PCA Skin Retinol Treatment for Sensitive Skin

    PCA Skin Retinol Treatment for Sensitive Skin

    Regular price
    $199.00
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    $199.00
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    $199.00
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  • Vivier Advanced Anti-Aging Program
    Vivier Advanced Anti-Aging Program Vivier Advanced Anti-Aging Program
    $307.00 Off

    Vivier Advanced Anti-Aging Program

    Regular price
    $648.00
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    $648.00
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    $955.00
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  • SkinCeuticals Hydrating B5 Gel
    SkinCeuticals Hydrating B5 Gel SkinCeuticals Hydrating B5 Gel

    SkinCeuticals Hydrating B5 Gel

    Regular price
    $120.00
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    $120.00
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    $120.00
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  • Neocutis Neo Firm
    Neocutis Neo Firm Neocutis Neo Firm

    Neocutis Neo Firm

    Regular price
    $160.00
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    $160.00
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  • Esthederm Intensive Pro-Collagen+ Cream
    Esthederm Intensive Pro-Collagen+ Cream Esthederm Intensive Pro-Collagen+ Cream

    Esthederm Intensive Pro-Collagen+ Cream

    Regular price
    $109.00
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    $109.00
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  • Esthederm Intensive Hyaluronic Cream
    Esthederm Intensive Hyaluronic Cream Esthederm Intensive Hyaluronic Cream

    Esthederm Intensive Hyaluronic Cream

    Regular price
    $108.00
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    $108.00
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  • GMC Medical Antioxidant 20 Anti-Aging Serum
    GMC Medical Antioxidant 20 Anti-Aging Serum

    GMC Medical Antioxidant 20 Anti-Aging Serum

    Regular price
    $180.00
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    $180.00
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  • GM Collin Aqua Mask
    GM Collin Aqua Mask GM Collin Aqua Mask

    GM Collin Aqua Mask

    Regular price
    $56.00
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    $56.00
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  • YonKa Glyconight 10% Masque
    YonKa Glyconight 10% Masque YonKa Glyconight 10% Masque

    YonKa Glyconight 10% Masque

    Regular price
    $110.00
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    $110.00
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  • NuFACE Hydrating Aqua Gel Activator (50ml)
    NuFACE Hydrating Aqua Gel Activator (50ml) NuFACE Hydrating Aqua Gel Activator (50ml)

    NuFACE Hydrating Aqua Gel Activator (50ml)

    Regular price
    $50.00
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    $50.00
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  • NuFACE IonPlex® Hydra-Gel Power Patches
    NuFACE IonPlex® Hydra-Gel Power Patches NuFACE IonPlex® Hydra-Gel Power Patches

    NuFACE IonPlex® Hydra-Gel Power Patches

    Regular price
    $75.00
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    $75.00
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  • NuFACE Prep-N-Glow® Dual-Sided Cloths (20 pack)
    NuFACE Prep-N-Glow® Dual-Sided Cloths (20 pack) NuFACE Prep-N-Glow® Dual-Sided Cloths (20 pack)

    NuFACE Prep-N-Glow® Dual-Sided Cloths (20 pack)

    Regular price
    $50.00
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    $50.00
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  • NuFACE Trinity+ Wrinkle Reducer Attachment
    NuFACE Trinity+ Wrinkle Reducer Attachment NuFACE Trinity+ Wrinkle Reducer Attachment

    NuFACE Trinity+ Wrinkle Reducer Attachment

    Regular price
    $215.00
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    $215.00
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  • FOREO Call It a Night UFO™ Activated Mask
    FOREO Call It a Night UFO™ Activated Mask FOREO Call It a Night UFO™ Activated Mask

    FOREO Call It a Night UFO™ Activated Mask

    Regular price
    $18.00
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    $18.00
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    $18.00
  • Alastin Restorative Skin Complex with TriHex Technology™
    Alastin Restorative Skin Complex with TriHex Technology™ Alastin Restorative Skin Complex with TriHex Technology™

    Alastin Restorative Skin Complex with TriHex Technology™

    Regular price
    $294.00
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    $294.00
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    $294.00
  • FOREO SUPERCHARGED Serum 2.0
    FOREO SUPERCHARGED Serum 2.0 FOREO SUPERCHARGED Serum 2.0

    FOREO SUPERCHARGED Serum 2.0

    Regular price
    $89.00
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    $89.00
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    $89.00
  • FOREO LUNA 4 Plus Smart Cleansing & Anti-Aging Device - Normal Skin
    FOREO LUNA 4 Plus Smart Cleansing & Anti-Aging Device - Normal Skin FOREO LUNA 4 Plus Smart Cleansing & Anti-Aging Device - Normal Skin

    FOREO LUNA 4 Plus Smart Cleansing & Anti-Aging Device - Normal Skin

    Regular price
    $599.00
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    $599.00
    Regular price
    $599.00
  • Teoxane RHA Deep Repair Balm
    Teoxane RHA Deep Repair Balm Teoxane RHA Deep Repair Balm

    Teoxane RHA Deep Repair Balm

    Regular price
    $99.00
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    $99.00
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    $99.00
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  • Teoxane RHA Perfect Skin Refiner
    Teoxane RHA Perfect Skin Refiner Teoxane RHA Perfect Skin Refiner

    Teoxane RHA Perfect Skin Refiner

    Regular price
    $180.00
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    $180.00
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    $180.00
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  • Teoxane RHA Advanced Filler for Normal Skin
    Teoxane RHA Advanced Filler for Normal Skin Teoxane RHA Advanced Filler for Normal Skin

    Teoxane RHA Advanced Filler for Normal Skin

    Regular price
    $160.00
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    $160.00
    Regular price
    $160.00
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  • Colorescience Pep Up Collagen Boost Face & Neck Serum
    Colorescience Pep Up Collagen Boost Face & Neck Serum Colorescience Pep Up Collagen Boost Face & Neck Serum

    Colorescience Pep Up Collagen Boost Face & Neck Serum

    Regular price
    $229.90
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    $229.90
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Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.