Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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498 products
  • Kala Therapy Red Light Face Mask
    Kala Therapy Red Light Face Mask Kala Therapy Red Light Face Mask

    Kala Therapy Red Light Face Mask

    Regular price
    $449.99
    Sale price
    $449.99
    Regular price
  • NuFACE FIX® Line Smoothing Serum
    NuFACE FIX® Line Smoothing Serum NuFACE FIX® Line Smoothing Serum

    NuFACE FIX® Line Smoothing Serum

    Regular price
    $69.00
    Sale price
    $69.00
    Regular price
    $69.00
    Earn 5% Cashback
  • Vivier Retinol 0.5%
    Vivier Retinol 0.5% Vivier Retinol 0.5%

    Vivier Retinol 0.5%

    Regular price
    $114.00
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    $114.00
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  • iS Clinical Retinol + Emulsion 0.3
    iS Clinical Retinol + Emulsion 0.3 iS Clinical Retinol + Emulsion 0.3

    iS Clinical Retinol + Emulsion 0.3

    Regular price
    $149.00
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    $149.00
    Regular price
    $149.00
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  • Alumier Brightening Collection Dry/Sensitive (with HQ)
    Alumier Brightening Collection Dry/Sensitive (with HQ)
    30% off

    Alumier Brightening Collection Dry/Sensitive (with HQ)

    Regular price
    $415.00
    Sale price
    $415.00
    Regular price
    $595.00
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  • Alumier Brightening Collection Normal/Oily (with HQ)
    Alumier Brightening Collection Normal/Oily (with HQ)
    30% off

    Alumier Brightening Collection Normal/Oily (with HQ)

    Regular price
    $415.00
    Sale price
    $415.00
    Regular price
    $595.00
    Earn 5% Cashback
  • Vivier Serum 10
    Vivier Serum 10 Vivier Serum 10

    Vivier Serum 10

    Regular price
    $126.00
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    $126.00
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  • Vivier GrenzCine® Serum
    Vivier GrenzCine® Serum Vivier GrenzCine® Serum

    Vivier GrenzCine® Serum

    Regular price
    $340.00
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    $340.00
    Regular price
    $334.00
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  • iS Clinical Moisturizing Complex
    iS Clinical Moisturizing Complex iS Clinical Moisturizing Complex

    iS Clinical Moisturizing Complex

    Regular price
    $141.00
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    $141.00
    Regular price
    $141.00
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  • Vivier Serum 30
    Vivier Serum 30 Vivier Serum 30

    Vivier Serum 30

    Regular price
    $220.00
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    $220.00
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  • Neocutis Bio Serum Firm
    Neocutis Bio Serum Firm Neocutis Bio Serum Firm

    Neocutis Bio Serum Firm

    Regular price
    $270.00
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    $270.00
    Regular price
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  • BABOR Best of Collagen Lifting Routine Set (Limited Edition)
    BABOR Best of Collagen Lifting Routine Set (Limited Edition) BABOR Best of Collagen Lifting Routine Set (Limited Edition)

    BABOR Best of Collagen Lifting Routine Set (Limited Edition)

    Regular price
    $180.00
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    $180.00
    Regular price
    $180.00
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  • GM Collin Hydramucine Optimal Gel
    GM Collin Hydramucine Optimal Gel GM Collin Hydramucine Optimal Gel

    GM Collin Hydramucine Optimal Gel

    Regular price
    $86.00
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    $86.00
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  • NuFACE FIX MicroWand
    NuFACE FIX MicroWand NuFACE FIX MicroWand

    NuFACE FIX MicroWand

    Regular price
    $264.00
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    $264.00
    Regular price
    $264.00
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  • FOREO Acai Berry Sheet Mask (3x)
    FOREO Acai Berry Sheet Mask (3x) FOREO Acai Berry Sheet Mask (3x)

    FOREO Acai Berry Sheet Mask (3x)

    Regular price
    $29.00
    Sale price
    $29.00
    Regular price
    $29.00
  • Colorescience Total Eye® Hydrogel Treatment Masks
    Colorescience Total Eye® Hydrogel Treatment Masks Colorescience Total Eye® Hydrogel Treatment Masks

    Colorescience Total Eye® Hydrogel Treatment Masks

    Regular price
    $116.00
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    $116.00
    Regular price
    $98.00
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  • DP Dermaceuticals CLR Lotion
    DP Dermaceuticals CLR Lotion DP Dermaceuticals CLR Lotion

    DP Dermaceuticals CLR Lotion

    Regular price
    $130.00
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    $130.00
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    $130.00
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  • COOLA Rōsilliance® Tinted Moisturizer Sunscreen SPF 30 Golden Hour
    COOLA Rōsilliance® Tinted Moisturizer Sunscreen SPF 30 Golden Hour COOLA Rōsilliance® Tinted Moisturizer Sunscreen SPF 30 Golden Hour

    COOLA Rōsilliance® Tinted Moisturizer Sunscreen SPF 30 Golden Hour

    Regular price
    $89.00
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    $89.00
    Regular price
    $89.00
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  • Teoxane RHA Vitamin C Serum
    Teoxane RHA Vitamin C Serum Teoxane RHA Vitamin C Serum

    Teoxane RHA Vitamin C Serum

    Regular price
    $230.00
    Sale price
    $230.00
    Regular price
    $230.00
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  • PCA Skin Nutrient Toner
    PCA Skin Nutrient Toner PCA Skin Nutrient Toner

    PCA Skin Nutrient Toner

    Regular price
    $68.00
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    $68.00
    Regular price
    $68.00
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  • Vivier Nightly Age-Defying Moisturizer
    Vivier Nightly Age-Defying Moisturizer Vivier Nightly Age-Defying Moisturizer

    Vivier Nightly Age-Defying Moisturizer

    Regular price
    $124.00
    Sale price
    $124.00
    Regular price
    Earn 5% Cashback
  • iS Clinical Super Serum Advanced+
    iS Clinical Super Serum Advanced+ iS Clinical Super Serum Advanced+

    iS Clinical Super Serum Advanced+

    Regular price
    $226.00
    Sale price
    $226.00
    Regular price
    $226.00
    Earn 5% Cashback
  • PCA Skin Retinol Treatment for Sensitive Skin
    PCA Skin Retinol Treatment for Sensitive Skin PCA Skin Retinol Treatment for Sensitive Skin

    PCA Skin Retinol Treatment for Sensitive Skin

    Regular price
    $199.00
    Sale price
    $199.00
    Regular price
    $199.00
    Earn 5% Cashback

Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.