Fine Lines & Wrinkles

Collection: Fine Lines & Wrinkles

Smooth the look of fine lines and wrinkles with targeted treatments that hydrate, firm, and support collagen production. Reveal visibly plumper, more youthful-looking skin.

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Fine Lines & Wrinkles Skincare in Canada

Explore clinically proven, medical-grade skincare formulated to smooth fine lines, boost collagen, and improve firmness. Shop professional-strength retinol, peptides, antioxidants, and growth factors from ZO Skin Health, Vivier, AlumierMD, SkinMedica and more — all available from WeDoSkin.ca, a Preferred Authorized Retailer in Canada.

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498 products
  • PCA Skin Hyaluronic Acid Overnight Mask
    PCA Skin Hyaluronic Acid Overnight Mask PCA Skin Hyaluronic Acid Overnight Mask

    PCA Skin Hyaluronic Acid Overnight Mask

    Regular price
    $117.00
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    $117.00
    Regular price
    $117.00
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  • GM Collin Native Collagen Gel
    GM Collin Native Collagen Gel GM Collin Native Collagen Gel

    GM Collin Native Collagen Gel

    Regular price
    $120.00
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    $120.00
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  • iS Clinical Active Peel System
    iS Clinical Active Peel System iS Clinical Active Peel System

    iS Clinical Active Peel System

    Regular price
    $132.00
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    $132.00
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    $132.00
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  • NuFACE MINI+ Device Starter Kit Sandy Rose
    NuFACE MINI+ Device Starter Kit Sandy Rose NuFACE MINI+ Device Starter Kit Sandy Rose

    NuFACE MINI+ Device Starter Kit Sandy Rose

    Regular price
    $340.00
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    $340.00
    Regular price
    $332.00
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  • TiZO® Photoceutical Advanced Vitamin C & E Serum
    TiZO® Photoceutical Advanced Vitamin C & E Serum TiZO® Photoceutical Advanced Vitamin C & E Serum

    TiZO® Photoceutical Advanced Vitamin C & E Serum

    Regular price
    $149.00
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    $149.00
    Regular price
    $149.00
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  • iS Clinical Pro-Health Serum Advanced+
    iS Clinical Pro-Health Serum Advanced+ iS Clinical Pro-Health Serum Advanced+

    iS Clinical Pro-Health Serum Advanced+

    Regular price
    $226.00
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    $226.00
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    $226.00
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  • iS Clinical Eclipse SPF50+ (PerfecTint Beige)
    iS Clinical Eclipse SPF50+ (PerfecTint Beige) iS Clinical Eclipse SPF50+ (PerfecTint Beige)

    iS Clinical Eclipse SPF50+ (PerfecTint Beige)

    Regular price
    $72.00
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    $72.00
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    $72.00
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  • EltaMD UV Sport SPF 50 Broad Spectrum (3 oz)
    EltaMD UV Sport SPF 50 Broad Spectrum (3 oz) EltaMD UV Sport SPF 50 Broad Spectrum (3 oz)

    EltaMD UV Sport SPF 50 Broad Spectrum (3 oz)

    Regular price
    $72.00
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    $72.00
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    $72.00
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  • YonKa Elastine Night Cream
    YonKa Elastine Night Cream YonKa Elastine Night Cream

    YonKa Elastine Night Cream

    Regular price
    $115.00
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    $115.00
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    $115.00
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  • Advanced Nutrition Programme Skin Omegas+ Travel Size (20 capsules)
    Advanced Nutrition Programme Skin Omegas+ Travel Size (20 capsules)

    Advanced Nutrition Programme Skin Omegas+ Travel Size (20 capsules)

    Regular price
    $21.00
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    $21.00
    Regular price
    $15.00
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  • NuFACE Hydrating Aqua Gel Activator (100ml)
    NuFACE Hydrating Aqua Gel Activator (100ml) NuFACE Hydrating Aqua Gel Activator (100ml)

    NuFACE Hydrating Aqua Gel Activator (100ml)

    Regular price
    $75.00
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    $75.00
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    $75.00
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  • Vivier Radiance Serum
    Vivier Radiance Serum Vivier Radiance Serum

    Vivier Radiance Serum

    Regular price
    $176.00
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    $176.00
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  • Teoxane RHA Advanced Filler Dry Skin
    Teoxane RHA Advanced Filler Dry Skin Teoxane RHA Advanced Filler Dry Skin

    Teoxane RHA Advanced Filler Dry Skin

    Regular price
    $160.00
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    $160.00
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    $160.00
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  • ZO Skin Health 10% Vitamin C Self-Activating
    ZO Skin Health 10% Vitamin C Self-Activating ZO Skin Health 10% Vitamin C Self-Activating

    ZO Skin Health 10% Vitamin C Self-Activating

    Regular price
    From $65.00
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    From $65.00
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  • ZO Skin Health Growth Factor Serum
    ZO Skin Health Growth Factor Serum ZO Skin Health Growth Factor Serum

    ZO Skin Health Growth Factor Serum

    Regular price
    $220.00
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    $220.00
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  • ZO Skin Health Next-Generation Daily Power Defense
    ZO Skin Health Next-Generation Daily Power Defense ZO Skin Health Next-Generation Daily Power Defense

    ZO Skin Health Next-Generation Daily Power Defense

    Regular price
    $230.00
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    $230.00
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  • FOREO FAQ 202 Anti-Aging Silicone LED Mask
    FOREO FAQ 202 Anti-Aging Silicone LED Mask FOREO FAQ 202 Anti-Aging Silicone LED Mask

    FOREO FAQ 202 Anti-Aging Silicone LED Mask

    Regular price
    $1,199.00
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    $1,199.00
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    $1,199.00
  • C Eye Serum Advance+
    C Eye Serum Advance+ C Eye Serum Advance+

    C Eye Serum Advance+

    Regular price
    $98.00
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    $98.00
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    $98.00
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  • Alumier Rejuvenating Collection - Normal/Oily
    Alumier Rejuvenating Collection - Normal/Oily
    22% off

    Alumier Rejuvenating Collection - Normal/Oily

    Regular price
    $490.00
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    $490.00
    Regular price
    $630.00
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  • Vivier SHEER SPF 30 Mineral Tinted
    Vivier SHEER SPF 30 Mineral Tinted Vivier SHEER SPF 30 Mineral Tinted

    Vivier SHEER SPF 30 Mineral Tinted

    Regular price
    $68.00
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    $68.00
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  • iS Clinical Youth Eye Complex
    iS Clinical Youth Eye Complex iS Clinical Youth Eye Complex

    iS Clinical Youth Eye Complex

    Regular price
    $144.50
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    $144.50
    Regular price
    $144.50
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  • iS Clinical Hydra-Cool Serum
    iS Clinical Hydra-Cool Serum iS Clinical Hydra-Cool Serum

    iS Clinical Hydra-Cool Serum

    Regular price
    $142.00
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    $142.00
    Regular price
    $142.00
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  • GM Collin Marine Collagen Revitalizing Cream
    GM Collin Marine Collagen Revitalizing Cream GM Collin Marine Collagen Revitalizing Cream

    GM Collin Marine Collagen Revitalizing Cream

    Regular price
    $120.00
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    $120.00
    Regular price
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Top 10 Medical-Grade Skincare Products for Fine Lines & Wrinkles (2026)

Addressing fine lines and wrinkles requires more than moisture — it’s about stimulating collagen, protecting against oxidative stress, and repairing the skin barrier. Based on dermatologist feedback and 2025 client satisfaction across Canadian clinics, these ten medical-grade products remain the leading choices for visible smoothness and firmness in 2026.

Each formula is supported by clinical research, expert formulation, and professional trust. For best results, use under the guidance of a licensed skincare professional, especially when introducing actives such as retinol, peptides, or Vitamin C.

At a Glance: 10 Best Professional-Grade Products for Fine Lines & Wrinkles

# Product Approx Price Tier Target Age Range Key Benefit
1 ZO Skin Health Growth Factor Serum $$–$$$ 30–60 yrs Peptides + growth factors visibly improve firmness & elasticity. Study
2 Vivier C E Peptides $$–$$$ 30–60 yrs Pharmaceutical Vitamin C + peptides support collagen. PubMed
3 AlumierMD Retinol Resurfacing Serum 1.0 $$ 25–50 yrs Encapsulated retinol smooths texture and fine lines.
4 SkinMedica TNS Advanced+ Serum $$$–$$$$ 35–65 yrs Dual-chamber growth factors clinically shown to firm skin. Clinical data
5 G.M. COLLIN Bota-Peptide Cream $$ 35–65 yrs Multi-peptide blend for smoother, firmer appearance.
6 ZO Retinol Skin Brightener 1% $$$ 28–60 yrs High-potency retinol + antioxidants for rejuvenation.
7 Vivier Radiance Serum $$ 25–55 yrs Arbutin + Vitamin C brighten & refine tone.
8 AlumierMD Ultimate Boost Serum $$ 25–55 yrs Hydrating peptides + niacinamide for barrier support.
9 Obagi Retinol 1.0 $$$ 30–60 yrs Stabilized retinol to refine texture and promote renewal.
10 SkinMedica HA5 Rejuvenating Hydrator $$$ 35–65 yrs Five forms of hyaluronic acid to smooth & plump instantly.

$$ = moderate (≈ CAD 80–200) | $$$ = premium (≈ CAD 200–350) | $$$$ = luxury (> CAD 350)

Educational Insights

According to JAMA Dermatology (2025), the most evidence-based ingredients for visible wrinkle reduction include retinoids, peptides, antioxidants, and growth factors. Retinoids boost collagen and cell renewal, while antioxidants like Vitamin C protect existing collagen from oxidative damage.

UV radiation remains the largest external cause of aging, responsible for up to 80% of visible wrinkles. Daily sunscreen, paired with clinically backed actives, helps maintain results and prevent new damage.

FAQs

Which ingredient is most effective for wrinkles?

Retinoids are the most proven anti-aging ingredient. They increase collagen, smooth texture, and reduce wrinkles over time.

Can Vitamin C and retinol be used together?

Yes. Use Vitamin C in the morning for antioxidant defense and retinol at night for cellular renewal to maximize benefits safely.

What age should I start anti-aging products?

Most dermatologists recommend antioxidants and SPF in your 20s, and retinoids or peptides in your early 30s as prevention and correction.

How long before I see results?

Visible improvements typically appear within 6–12 weeks; full collagen remodeling can take 3–6 months of consistent use.

Our take

Fine lines and wrinkles are natural — but science-driven skincare can visibly enhance texture, tone, and firmness. At WeDoSkin.ca, a Preferred Authorized Retailer for medical-grade skincare in Canada, every product is authentic, fresh, and supported by expert guidance. Explore our Fine Lines & Wrinkles Collection to start your personalized anti-aging routine today.