SkinCeuticals A.G.E. Interrupter Advanced
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- Regular price
- $240.00
- Sale price
- $240.00
- Regular price
- $240.00
SkinCeuticals’ best-selling anti-aging cream, A.G.E. Interrupter Advanced targets wrinkles, skin laxity, and dullness to restore a firmer, more radiant complexion.
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Description
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Key Benefits
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How to use
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Ingredients
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Frequently Asked Questions
Description
Size: 48 ml / 1.7 fl. oz.
Recommended For: Dry • Combination • Sensitive • Normal • Aging
A Best-Selling Anti-Aging Cream
A.G.E. Interrupter Advanced is a powerful corrective treatment designed to reverse the visible signs of aging caused by collagen breakdown and glycation. These signs include wrinkles, skin laxity, and dullness.
This next-generation anti-aging cream features 18% concentrated Proxylane™—20% increase in active concentration compared to the original formula—alongside a 4.25% wild fruit flavonoid blend, now 12.5% more potent. The formula also includes new key actives such as 0.1% glycyrrhetinic acid.
Clinically shown to reduce the appearance of five types of wrinkles—forehead wrinkles, glabellar lines, crow’s feet, nasolabial folds, and marionette lines—this advanced moisturizer works to restore firmness and elasticity while improving skin tone and radiance.
SkinCeuticals A.G.E. Interrupter Advanced — FAQs
What does A.G.E. Interrupter Advanced target?
It targets visible aging from collagen breakdown and glycation — wrinkles, laxity, and dullness — with 18% Proxylane™ and a 4.25% wild fruit flavonoid blend to restore firmness and elasticity.
What is glycation and why does it matter for aging skin?
Glycation is when sugars bind to collagen and elastin, stiffening them and accelerating wrinkles and sagging. A.G.E. Interrupter Advanced is formulated specifically to help counter this process in mature skin.
How do I use it?
Apply a small amount morning and/or evening as the last step of your routine, over serums. Follow with SPF in the morning.
Is it authentic and shipped in Canada?
Yes. WeDoSkin is an authorized Canadian retailer shipping authentic, fresh A.G.E. Interrupter Advanced Canada-wide.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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For 20 years now, I just keep coming back to this foundation. Every now & then, I’d try something cleaner, purer, but I return to Jane Iredale’s Purepressed Base because, frankly, it’s the best. This finely milled product looks better and better throughout the day and it lasts at the beach, in the ocean or a pool, and I always get compliments on my skin, not my makeup. It’s what they call “a keeper” or “an oldie but a goodie”, kinda like me. Just get it.
This is my favorite Vit C product because its effects are noticeable: it brightens, tightens and smooths. If I don’t use it for awhile I notice my skin doesn’t look as good.
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SkinCeuticals A.G.E. Interrupter Advanced: Target Glycation and Five Types of Wrinkles
A.G.E. Interrupter Advanced is a powerful corrective cream designed to reverse the visible signs of aging caused by collagen breakdown and glycation — wrinkles, laxity, and dullness.
It features 18% concentrated Proxylane, a 4.25% wild fruit flavonoid blend, and 0.1% glycyrrhetinic acid, clinically shown to reduce five types of wrinkles. WeDoSkin.ca is an Authorized SkinCeuticals Retailer in Canada, with authentic, fresh stock.
18% Proxylane
Higher active concentration.
Wild Fruit Flavonoids
Target glycation damage.
Reduces 5 Wrinkles
Forehead to marionette lines.
Firms & Restores
Improves elasticity and tone.
Key Ingredients & How They Work
The actives that drive A.G.E. Interrupter Advanced — and what each one does for your skin.
Firming
Higher concentration than original.
Anti-Glycation
More potent wild fruit blend.
Active
New corrective key active.
A.G.E.s
Targets glycation-related aging.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of A.G.E. Interrupter Advanced
What A.G.E. Interrupter Advanced Pairs Well With
Build a complete routine — these pairings are most often recommended alongside A.G.E. Interrupter Advanced. Tap any product to shop.
SkinCeuticals C E Ferulic — New 2026 Formula$230.00Shop now →
SkinCeuticals H.A. Intensifier Multi-Glycan$175.00Shop now →
SkinCeuticals Triple Lipid Restore 2:4:2$195.00Shop now →
SkinCeuticals Physical Fusion UV Defense SPF 50$68.00Shop now →How to Use
- Apply to clean skin morning and/or night as your moisturiser.
- Layer over serums; massage in fully.
- Follow with SPF in the morning.
Who It's For
- Dry, normal, sensitive, aging skin
- Wrinkles and skin laxity
- Glycation-related dullness
- Those wanting corrective anti-aging
Sensitivity note: A corrective anti-aging cream suitable for dry, normal, and sensitive aging skin; pair with daily SPF.
How A.G.E. Interrupter Advanced Compares
Where A.G.E. Interrupter Advanced sits relative to other options. The right fit depends on your skin and goals.
| Feature | A.G.E. Interrupter Advanced | Triple Lipid Restore | Resveratrol B E |
|---|---|---|---|
| Focus | Glycation + wrinkles | Barrier + lipids | Overnight repair |
| Hero | 18% Proxylane | Ceramides + lipids | Resveratrol |
| Type | Moisturiser | Moisturiser | Night serum |
| Best for | Wrinkles + laxity | Dry/compromised | Radiance |
A.G.E. Interrupter Advanced: Frequently Asked Questions
Should I use A.G.E. Interrupter or Triple Lipid Restore?
This is the most common question! Choose Triple Lipid Restore if your main issues are dryness, a damaged skin barrier, or you are peeling from Retinol use. Choose A.G.E. Interrupter Advanced if your main issues are deep wrinkles, sagging skin, crepiness, and a loss of facial firmness.
What are the 5 types of wrinkles it targets?
Clinical trials show this formula significantly improves the appearance of: Forehead wrinkles, Glabellar lines (the '11s' between the brows), Crow's feet around the eyes, Nasolabial folds (smile lines), and Marionette lines (from the mouth to the chin).
Is this good for crepey skin on the neck?
Yes, absolutely. Because crepey skin is a direct result of collagen glycation and thinning tissue, the 18% Proxylane in this formula is exceptionally effective at restoring thickness and bounce to the delicate skin on the neck and chest.
What is the difference between this 'Advanced' version and the original?
SkinCeuticals upgraded the formula to include a higher concentration of wild fruit flavonoids (now 4.25%) and added Glycyrrhetinic Acid. This means the 'Advanced' version provides stronger anti-glycation defense and improves skin radiance significantly faster than the original A.G.E. Interrupter.
Can I use this cream if I have acne-prone skin?
A.G.E. Interrupter is a rich, emollient cream formulated for mature and thinning skin. While it is non-comedogenic, it is often too heavy for active, oily, or acne-prone skin. It is best suited for normal, dry, and aging skin types.
Can I layer this over Retinol?
Yes! It is highly complementary. Apply your retinol serum first, allow it to fully absorb into the skin, and then seal it in with a layer of A.G.E. Interrupter to maximize your anti-aging benefits and prevent moisture loss overnight.
Is it too heavy for daytime use?
Not at all. Despite being highly nourishing, the cream has a silky, elegant finish that absorbs completely into the skin without leaving a greasy residue. It sits beautifully under sunscreen and makeup during the day.
Is it safe for use during pregnancy?
Yes. A.G.E. Interrupter focuses on glycation and collagen support using Proxylane and fruit flavonoids. It does not contain retinoids or aggressive systemic chemicals, making it widely considered safe for use during pregnancy. (Always consult your healthcare provider).
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
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