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Epicutis Hydrobiome Serum

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$220.00
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$220.00
Regular price
$220.00
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A next generation microbiome balancing serum designed to calm inflammation, strengthen the barrier, and restore resilient skin.

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  • Description

  • Key Benefits

  • How to use

  • Ingredients

  • Frequently Asked Questions

Description

Size: 50 mL

Skin Concerns: Redness, inflammation, breakouts, barrier damage, microbiome imbalance, sensitivity

Skin Types: All skin types, including sensitive and acne prone skin

Texture: Lightweight fast absorbing serum

 

 

Balance the Microbiome. Calm Inflammation. Restore Resilient Skin.

 

Epicutis Hydrobiome Serum is a next generation microbiome balancing treatment designed to restore skin health by calming inflammation, strengthening the skin barrier, and supporting long term microbiome harmony. This advanced EWG Verified formulation combines clinically proven actives that work synergistically to improve skin resilience while targeting visible redness, irritation, and microbiome related breakouts.


At the core of the formula is TCP, a patented TLR2 modulator developed by Signum Biosciences that helps regulate inflammatory signaling while targeting C. acnes and supporting beneficial skin flora. Paired with TPNa, an advanced water soluble form of Vitamin E, the serum delivers antioxidant protection while reinforcing the skin’s natural barrier against environmental stressors.


Lightweight and fast absorbing, Hydrobiome Serum delivers immediate comfort while supporting healthier, calmer, and visibly more resilient skin over time. Ideal for compromised barriers, reactive skin, post treatment recovery, or anyone seeking balanced, healthy skin function.

Key Benefits

How to use

Ingredients

Frequently Asked Questions

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Epicutis Hydrobiome Serum: Balance, Calm, Restore

A next-generation microbiome-balancing treatment that calms inflammation, strengthens the barrier and supports long-term microbiome harmony.

At its core is TCP, a patented TLR2 modulator that regulates inflammatory signaling and targets C. acnes, paired with TPNa, a water-soluble vitamin E for antioxidant defense. WeDoSkin.ca is a Preferred Authorized Retailer for Epicutis in Canada, with authentic, fresh stock.

🦠

Microbiome Balance

Supports beneficial flora and long-term harmony.

🔬

Patented TCP

A TLR2 modulator that calms inflammation and targets C. acnes.

🛡️

Antioxidant Defense

TPNa vitamin E protects against environmental stress.

🌿

Calms Redness

Reduces visible redness and irritation.

Key Ingredients & How They Work

The actives that drive Microbiome-balancing serum with patented TCP that calms redness and breakouts. — and what each one does for your skin.

TCP

TCP Modulator

Patented TLR2 modulator from Signum Biosciences.

TPNa

Water-Soluble Vit E

Delivers antioxidant protection and barrier support.

EWG

EWG Verified

Clean formulation you can trust.

Flora

Microbiome Support

Encourages a balanced, resilient skin surface.

These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Benefits of Microbiome-balancing serum with patented TCP that calms redness and breakouts.

Balances the skin microbiome
Calms redness and inflammation
Targets microbiome-related breakouts
Strengthens the skin barrier
Antioxidant protection from vitamin E
Lightweight and fast-absorbing

What Microbiome-balancing serum with patented TCP that calms redness and breakouts. Pairs Well With

Build a complete routine — these pairings are most often recommended alongside Microbiome-balancing serum with patented TCP that calms redness and breakouts.. Tap any product to shop.

How to Use

  1. Apply to clean skin morning and evening.
  2. Smooth over the face before moisturizer.
  3. Use daily for calmer, more balanced skin.

Who It's For

  • Redness, irritation and sensitivity
  • Microbiome-related breakouts
  • Compromised or reactive barriers
  • Post-treatment recovery

Sensitivity note: EWG Verified and suitable for all skin types, including sensitive and acne-prone. Gentle enough for daily use.

How Microbiome-balancing serum with patented TCP that calms redness and breakouts. Compares

Where Microbiome-balancing serum with patented TCP that calms redness and breakouts. sits relative to other options. The right fit depends on your skin and goals.

Microbiome-balancing serum with patented TCP that calms redness and breakouts. vs the Alternatives
ProductFocusKey TechBest For
Hydrobiome SerumMicrobiome balanceTCP, TPNaBreakouts, redness
Lipid SerumBarrier repairBiomimetic lipids, TSCReactive skin
Hydrobiome MistHydrate and calmProbioticsMidday reset
Hyvia CremeLipid moistureHYVIA blue-lightDryness

Microbiome-balancing serum with patented TCP that calms redness and breakouts.: Frequently Asked Questions

What does the Hydrobiome Serum do?

It balances the skin microbiome while calming inflammation and strengthening the barrier, using the patented TCP modulator and antioxidant vitamin E.

Does it help breakouts?

Yes. TCP targets C. acnes and regulates inflammation, helping with microbiome-related breakouts while supporting beneficial skin flora.

Is it gentle enough for sensitive skin?

Yes. It is EWG Verified and suitable for all skin types, including sensitive and acne-prone skin.

How is it different from the Lipid Serum?

Hydrobiome focuses on microbiome balance and calming breakouts, while the Lipid Serum focuses on rebuilding the barrier with biomimetic lipids. They layer well together.

When should I use it?

Morning and night on clean skin, before moisturizer, for calmer and more balanced skin over time.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.

Last reviewed March 18, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

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