NeoGenesis Body Cream

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Body Cream is the NeoGenesis moisturizer for everything below the jawline: dry, crepey and sensitive skin on the arms, legs, elbows, knees, hands and chest.

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NeoGenesis Body Cream (30mL)
NeoGenesis Body Cream (120mL)
NeoGenesis Body Cream (5mL)
  • NeoGenesis Body Cream (30mL)
  • NeoGenesis Body Cream (120mL)
  • NeoGenesis Body Cream (5mL)
NeoGenesis Body Cream (30mL)
NeoGenesis Body Cream (120mL)
NeoGenesis Body Cream (5mL)
  • Description

  • Key Benefits

  • How to use

  • Ingredients

  • Frequently Asked Questions

Description

Size: 5 mL / 30 mL / 120 mL

Skin Types: Dry, Sensitive Skin, Mature skin, Normal

Skin Concerns: Dry, rough body skin, crepey-looking skin, sensitive skin, mature and aging skin, arms, legs, elbows, knees, hands and chest, environmentally stressed skin

Body Cream brings NeoGenesis regenerative skincare below the jawline. It is powered by 5% S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, so the same growth factors, heat shock proteins, immune modulators and antioxidants found in the face serums support smoother, firmer-looking skin on the body. Natural Moisturizing Factors, safflower oleosomes and a unique butyrate form of hyaluronic acid handle the moisture.


Despite how much it delivers, the texture stays lightweight and non-greasy. Urea, sodium PCA, glycerin, squalane and sodium hyaluronate replenish dry skin and support the natural moisture barrier, then the cream absorbs quickly to leave skin soft, smooth and nourished with a well-rested glow. NeoGenesis recommends it twice daily, all over the body, layered over Recovery, Booster or Skin Serum wherever skin needs more.

Watch: Body Cream explained

NeoGenesis made this short product video for Body Cream, so you can see the texture, the application and where it fits in a routine before you buy.

Real results with Body Cream

NeoGenesis publishes before and after photos from its professional partners. These cases used Body Cream as part of a NeoGenesis routine, and each caption lists every product involved.

Visible signs of aging, neck. Products used: Cleanser, Recovery, Eye Serum, Body Cream, Moisturizing Mist. Photos courtesy of NeoGenesis.

Visible signs of aging, neck. Products used: Cleanser, Recovery, Eye Serum, Body Cream, Moisturizing Mist.

Photos courtesy of NeoGenesis. Individual results vary.

She looks forward to seeing more progress!Shared by NeoGenesis
Blemish-prone skin. Products used: Cleanser, Moisturizing Mist, Recovery, Eye Serum and more. Photos courtesy of NeoGenesis.

Blemish-prone skin. Products used: Cleanser, Moisturizing Mist, Recovery, Eye Serum and more.

Photos courtesy of NeoGenesis. Individual results vary.

Loves all the products!Shared by NeoGenesis

Photos courtesy of NeoGenesis professional partners. Individual results vary.

Key Benefits

How to use

Ingredients

Frequently Asked Questions

Recommended Products

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Body Cream: hydrate and rejuvenate with 5% S2RM

Body Cream is the NeoGenesis moisturizer for everything below the jawline: dry, crepey and sensitive skin on the arms, legs, elbows, knees, hands and chest. It is powered by 5% S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, so the body gets the same growth factors, heat shock proteins, immune modulators and antioxidants that support the appearance of tone, texture and firmness in the face serums.

The moisture side is built from skin-native pieces: Natural Moisturizing Factors like urea and sodium PCA, glycerin, squalane, safflower oleosomes and a unique butyrate form of hyaluronic acid that hydrates while delivering a postbiotic associated with calmer-looking skin. Even so, the cream is lightweight and non-greasy, absorbs quickly and leaves skin soft, smooth and nourished with a fresh glow. Apply it twice daily, on its own or over an S2RM serum.

🧬

5% S2RM for the body

Growth factors, heat shock proteins, immune modulators and antioxidants help improve the appearance of overall tone and texture for smoother, firmer-looking skin.

✨

Lasting hydration

Skin-native hydrators and emollients replenish dry skin while supporting the skin's natural moisture barrier.

💧

Silky, non-greasy finish

Absorbs quickly and leaves skin soft, smooth and nourished with a fresh-looking glow, not a film.

🛡️

Head to toe

Made for dry, crepey, sensitive and mature skin anywhere on the body, twice a day.

Key Ingredients & How They Work

The actives that drive 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe. — and what each one does for your skin.

SKINSPECIFIC EXOSOMES

Skin-specific exosomes

The stem cell conditioned media carries released molecules from exosomes, ectosomes and the soluble fraction of fibroblast and adipose stem cells, which help return skin to a more balanced, youthful-looking state.

SODIUM HYALURONATE

Sodium hyaluronate butyrate

A skin-native form of hyaluronic acid that hydrates while delivering butyrate, a beneficial postbiotic associated with calmer-looking skin, improved comfort and barrier support.

NATURAL MOISTURIZING

Natural Moisturizing Factors

Urea and sodium PCA, with glycerin and sodium hyaluronate, replenish the hydration that dry, rough skin is missing.

SAFFLOWER OLEOSOMES

Safflower oleosomes and squalane

Natural liposomes deliver moisturizing factors that strengthen the barrier and promote resilience, while squalane and triglycerides give a soft, non-greasy feel.

These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Benefits of 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe.

Deeply moisturizes dry, rough and crepey-looking skin
Supports smoother, firmer-looking skin with 5% S2RM
Helps improve the appearance of overall tone and texture
Supports the skin's natural moisture barrier
Lightweight, non-greasy and fast absorbing
Suitable for sensitive and mature skin

What 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe. Pairs Well With

Build a complete routine — these pairings are most often recommended alongside 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe.. Tap any product to shop.

How to Use

  1. Apply all over the body, paying attention to arms, legs, elbows, knees, hands and chest.
  2. For best results apply twice daily.
  3. Layer over Recovery, Booster or Skin Serum on areas that need extra support. Available in 5 mL, 30 mL and 120 mL.

Who It's For

  • Dry, rough skin that a regular lotion never quite fixes
  • Crepey-looking or mature skin on the arms, chest, hands and legs
  • Sensitive body skin that wants a lightweight, fast-absorbing cream
  • Anyone extending their NeoGenesis routine from the face to the body

Sensitivity note: Made for dry and sensitive skin and lightweight enough for daily, twice-daily use. Note that the formula includes orange oil, so patch test first if your skin reacts to essential oils.

How 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe. Compares

Where 5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe. sits relative to other options. The right fit depends on your skin and goals.

5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe. vs the Alternatives
FeatureNeoGenesis Body CreamProfessional Body CreamsDrugstore Body Lotions
Active technology5% S2RM: growth factors, heat shock proteins, immune modulators and antioxidants from two stem cell sourcesFace-only growth factor serum, rarely made for the bodyNo growth factor or exosome content
HydrationUrea, sodium PCA, glycerin, squalane, sodium hyaluronate and sodium hyaluronate butyrateHyaluronic acidGlycerin and mineral oil or petrolatum
TextureLightweight, non-greasy, absorbs quicklySerum texture, not a moisturizerOften heavy or sticky
Skin type rangeDry, crepey, sensitive and mature skinVariesGeneral dry skin

5% S2RM body cream for dry, crepey and sensitive skin: lightweight, non-greasy, head to toe.: Frequently Asked Questions

What is the best body cream for dry skin?

The best cream for dry skin gives long-lasting hydration while replenishing the skin's natural moisture barrier. NeoGenesis Body Cream combines urea, sodium hyaluronate and 5% S2RM technology to deeply moisturize rough, dry skin while supporting a softer, smoother, more balanced-looking appearance.

What makes NeoGenesis Body Cream different from other body creams?

Most body creams only moisturize. NeoGenesis Body Cream pairs advanced hydrators with 5% S2RM exosome technology to support smoother, firmer and more resilient-looking skin at the same time. That combination is why it suits dry, mature and environmentally stressed skin so well.

Body lotion vs body cream: which should I use?

Lotions are lighter and absorb quickly; creams carry a richer blend of moisturizing ingredients for longer-lasting hydration. NeoGenesis Body Cream is formulated to deeply moisturize dry skin while staying comfortable and non-greasy enough for everyday use, so you get the cream's staying power without the lotion trade-off.

Can I use Body Cream every day?

Yes. NeoGenesis recommends it twice daily. It is especially useful for dry, rough or mature skin and for areas that commonly lose moisture, including the arms, legs, elbows, knees, hands and chest. Consistent use keeps skin feeling hydrated, comfortable and well-balanced.

What is a regenerative body cream?

A regenerative body cream combines advanced moisturizing ingredients with technologies designed to support skin that looks and functions at its best. NeoGenesis Body Cream does this with 5% S2RM technology, stem cell released molecules, alongside nourishing hydrators for long-lasting moisture in a daily body care routine.

Can I use Body Cream with a NeoGenesis serum?

Yes. NeoGenesis pairs Body Cream with Recovery, Booster and Skin Serum. Apply the serum first to areas that need extra support, such as crepey skin on the chest or hands, then seal it in with Body Cream.

Are there before and after photos for Body Cream?

Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Body Cream is shown above with every product in the routine listed in the caption. Individual results vary.

Is there a video on how to use Body Cream?

Yes. The NeoGenesis product video above walks through Body Cream, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.

Last reviewed March 18, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

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