SkinCeuticals P-TIOX
- Regular price
- $200.00
- Sale price
- $200.00
- Regular price
- $200.00
Formulated for all skin types with visible expression lines, P-TIOX delivers advanced, needle-free peptide correction to improve wrinkles, firmness, and skin texture.
Trusted by 100,000+ Canadians
Excellent · Verified Reviews
-
Description
-
Key Benefits
-
How to use
-
Ingredients
-
Frequently Asked Questions
Description
A needle-free peptide serum for expression lines and glass skin radiance
Size: 30 mL / 1 fl. oz.
Suitable for all skin types and tones, including dry, normal, oily, combination, sensitive, aging, and fine lines & wrinkles.
Targeted concerns: Expression lines, fine lines, wrinkles, uneven texture, enlarged pores, dehydrated skin
P-TIOX is a high-performance, needle-free peptide serum clinically proven to outperform standard peptide-based formulas for advanced wrinkle correction. Powered by an amplified Argireline complex, and enhanced with niacinamide, PHA, and Laminaria Extract, this lightweight serum targets 9 types of expression lines—including areas typically untouched by injectables. It visibly smooths, firms, and refines skin texture, while revealing a radiant, glass-like finish. Suitable for all skin types, including sensitive, P-TIOX is ideal both as a stand-alone anti-wrinkle solution and as a complement to neuromodulator injections.
Visible Results
P-TIOX is clinically proven to reduce the appearance of 9 types of expression
wrinkles and reveal glass skin radiance.
After 1 week:
Visibly improves skin smoothness, refines the look of pores, and reveals glass
skin radiance
After 12 weeks:
Visibly reduces 9 types of expression wrinkles, even those neuromodulators
generally do not treat:
- Nasolabial folds
- Forehead wrinkles
- Glabellar wrinkles
- Crow’s feet wrinkles
- Cheek folds wrinkles
- Marionette wrinkles
- Dynamic under-eye wrinkles
- Inter-ocular wrinkles
- Global fine lines

- 27% improvement in radiance
- 29% improvement in smoothness
- 42% reduction in pore appearance
- 29% improvement in smoothness
- 42% reduction in pore appearance
- 32% improvement in elasticity
- 42% reduction in pore appearance
- 32% improvement in elasticity
- 36% improvement in firmness
Key Benefits
How to use
Ingredients
Frequently Asked Questions
45 Day Satisfaction Guarantee with Checkout+
Try your new skincare routine and devices. If you're not satisfied, return them within 45 days for a full refund or exchange.
- Free return labels
- Your 45 days begin upon delivery
To qualify, you must select Checkout+ during purchase. If you do not select Checkout+, standard return policy applied.
Recommended Products
You might also like these
Let customers speak for us
- Preferred Authorized Retailer
- 100,000+ Happy Customers
- Earn 5% Cashback
- 100-Day Returns*
- Free Samples
SkinCeuticals P-TIOX: Needle-Free Peptide Serum for Expression Lines
SkinCeuticals P-TIOX is a high-performance, needle-free peptide serum clinically proven to outperform standard peptide formulas, targeting nine types of expression lines including areas injectables often miss.
Powered by an amplified Argireline complex with niacinamide, PHA, and Laminaria extract, it smooths, firms, and reveals glass-skin radiance — suitable for all skin types. WeDoSkin.ca is an Authorized SkinCeuticals Retailer in Canada, with authentic, fresh stock.
Needle-Free
Targets 9 expression lines.
Amplified Argireline
Advanced peptide complex.
Glass-Skin Glow
Smoother, radiant finish.
Clinically Proven
Visible results in 1 week.
Key Ingredients & How They Work
The actives that drive P-TIOX — and what each one does for your skin.
Peptides
Amplified for expression lines.
Refining
Evens tone and texture.
Smoothing
Gently refines the surface.
Firming
Supports a sculpted look.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of P-TIOX
What P-TIOX Pairs Well With
Build a complete routine — these pairings are most often recommended alongside P-TIOX. Tap any product to shop.
SkinCeuticals P-TIOX Anti-Wrinkle Cream$225.00Shop now →
SkinCeuticals C E Ferulic$230.00Shop now →
SkinCeuticals H.A. Intensifier Multi-Glycan$175.00Shop now →
SkinCeuticals Physical Fusion UV Defense SPF 50$68.00Shop now →How to Use
- Apply to clean skin morning and night before moisturiser.
- Pair with P-TIOX Cream for best results.
- Follow with SPF in the morning.
Who It's For
- Expression lines and wrinkles
- Enlarged pores and texture
- Loss of firmness and dullness
- All skin types incl sensitive
Sensitivity note: A needle-free peptide serum suitable for all skin types and tones, including sensitive; pair with daily SPF.
How P-TIOX Compares
Where P-TIOX sits relative to other options. The right fit depends on your skin and goals.
| Feature | P-TIOX Serum | P-TIOX Cream | AGE Interrupter Ultra Serum |
|---|---|---|---|
| Type | Peptide serum | Moisturiser | Lifting serum |
| Hero | Argireline complex | Myrixin + tripeptide | 34.6% Flavo-Proxylane |
| Focus | Expression lines | Wrinkles + pores | Lift + firmness |
| Pairs with | P-TIOX Cream | P-TIOX Serum | Vitamin C |
P-TIOX: Frequently Asked Questions
Is P-TIOX a replacement for professional neuromodulator injections?
While P-TIOX is incredibly powerful, no topical serum can entirely replace professional neurotoxin injections. Instead, P-TIOX acts as the ultimate 'injectable extender.' It complements your in-clinic treatments by targeting dynamic lines in areas where needles often aren't used (like cheek folds, under-eyes, and the neck), while prolonging the life of your injectables.
What exactly is the 'Glass Skin' effect?
Glass skin refers to a complexion so smooth, clear, and intensely hydrated that it appears almost transparent and reflective like glass. P-TIOX achieves this by pairing peptides with 5% Polyhydroxy Acid (PHA) to gently polish away dead cells, and 5% Niacinamide to shrink pores, leaving a flawless, glowing surface.
Can I use P-TIOX if I don't get injectables?
Absolutely! It acts as a phenomenal needle-free alternative for anyone looking to treat expression lines, deep wrinkles, and textural dullness without stepping into a medical clinic.
What are the 9 types of contraction lines it targets?
Clinical studies show P-TIOX visibly reduces: 1) Forehead lines, 2) Glabellar lines ('11s' between the brows), 3) Crow's feet, 4) Under-eye wrinkles, 5) Cheek folds, 6) Nasolabial folds (smile lines), 7) Marionette lines, 8) Dynamic lip lines, and 9) Neck lines.
Can I use P-TIOX in the same routine as Retinol and Vitamin C?
Yes, P-TIOX is highly synergistic. In the morning, apply it after your Vitamin C (C E Ferulic) and before sunscreen. At night, it can safely be applied before or after your Retinol to boost anti-aging benefits without causing irritation.
How does the Advanced Peptide Complex work?
The proprietary blend of Hexapeptide and Dipeptide works topically to interfere with the neurotransmitter signals that tell facial muscles to contract. By 'relaxing' this signaling on a surface level, the skin creases less, allowing dynamic wrinkles to soften and fade over time.
Is P-TIOX suitable for sensitive or rosacea-prone skin?
Yes. Because it uses PHA (Polyhydroxy Acid) instead of stronger AHAs like glycolic acid, it provides necessary exfoliation and texture refinement without triggering redness or stinging. The 5% Niacinamide also actively calms the skin barrier.
How quickly will I see results with P-TIOX?
You will see a visible improvement in skin radiance, texture, and the 'glass skin' finish within the very first week. Significant clinical reduction in deep contraction lines is scientifically proven after 12 weeks of twice-daily use.
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
Explore Related Concerns & Ingredients
The concern and ingredient hubs P-TIOX most often appears in at WeDoSkin.
Why Canadians Choose WeDoSkin
Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.
Questions about P-TIOX?
Connect with a WeDoSkin clinical expert for a complimentary consultation.
Contact Our Skincare Experts