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Best Medical-Grade Serums in Canada

Serums are the treatment engine of a routine, delivering high concentrations of actives like vitamin C, retinol, peptides and hyaluronic acid deep into the skin. The best approach is to layer a targeted serum after cleansing and before moisturiser, choosing actives matched to your main concern. Shop medical-grade serums and facial oils from professional brands including SkinCeuticals, AlumierMD, Vivier, ZO Skin Health and iS Clinical — authentic and authorized in Canada.

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  • ( plated )™ Hair Science Hair Serum ( plated )™ Hair Science Hair Serum

    ( plated )™ Hair Science Hair Serum

    $530.00
    $530.00
    $530.00
    Earn 5% Cashback
    ( plated ) Skin Science
  • Alastin C-RADICAL Defense Antioxidant Serum Alastin C-RADICAL Defense Antioxidant Serum

    Alastin C-RADICAL Defense Antioxidant Serum

    $218.00
    $218.00
    $218.00
    Alastin
  • Alastin A-Luminate Brightening Serum Alastin A-Luminate Brightening Serum

    Alastin A-Luminate Brightening Serum

    $240.00
    $240.00
    $240.00
    Alastin
  • Alumier Ultimate Boost Serum Alumier Ultimate Boost Serum

    Alumier Ultimate Boost Serum

    $141.00
    $141.00
    Earn 5% Cashback
    All Products
  • Alumier Retinol Resurfacing Serum 1.0% Alumier Retinol Resurfacing Serum 1.0%

    Alumier Retinol Resurfacing Serum 1.0%

    $153.00
    $153.00
    Earn 5% Cashback
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  • SkinCeuticals C E Ferulic — New 2026 Formula SkinCeuticals C E Ferulic — New 2026 Formula

    SkinCeuticals C E Ferulic — New 2026 Formula

    $230.00
    $230.00
    $230.00
    Earn 5% Cashback
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  • Alumier Intellibright Complex Alumier Intellibright Complex

    Alumier Intellibright Complex

    $136.00
    $136.00
    Earn 5% Cashback
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  • Alumier Calm-R® Alumier Calm-R®

    Alumier Calm-R®

    $158.00
    $158.00
    Earn 5% Cashback
    All Products
  • SkinCeuticals P-TIOX — Needle-Free Anti-Wrinkle Serum SkinCeuticals P-TIOX — Needle-Free Anti-Wrinkle Serum

    SkinCeuticals P-TIOX — Needle-Free Anti-Wrinkle Serum

    $200.00
    $200.00
    $200.00
    Earn 5% Cashback
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  • Alumier Retinol Resurfacing Serum 0.5% Alumier Retinol Resurfacing Serum 0.5%

    Alumier Retinol Resurfacing Serum 0.5%

    $139.00
    $139.00
    Earn 5% Cashback
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  • Alumier Retinol Resurfacing Serum 0.25% Alumier Retinol Resurfacing Serum 0.25%

    Alumier Retinol Resurfacing Serum 0.25%

    $118.50
    $118.50
    Earn 5% Cashback
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  • Alumier Alumience A.G.E.™ Alumier Alumience A.G.E.™

    Alumier Alumience A.G.E.™

    $176.00
    $176.00
    Earn 5% Cashback
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  • Alumier AHA Renewal Serum Alumier AHA Renewal Serum

    Alumier AHA Renewal Serum

    $119.00
    $119.00
    Earn 5% Cashback
    AHAs (Glycolic Acid/Lactic Acid)
  • XYON Revitalize Hair-Boosting Serum for Women XYON Revitalize Hair-Boosting Serum for Women

    XYON Revitalize Hair-Boosting Serum for Women

    $72.00
    $72.00
    Earn 5% Cashback
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  • Vivier C E Peptides Vivier C E Peptides

    Vivier C E Peptides

    $222.00
    $222.00
    $222.00
    Earn 5% Cashback
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  • Alumier Acne Balancing Serum Alumier Acne Balancing Serum

    Alumier Acne Balancing Serum

    $103.00
    $103.00
    Earn 5% Cashback
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  • ( plated )™ Skin Science Intense Serum ( plated )™ Skin Science Intense Serum

    ( plated )™ Skin Science Intense Serum

    $370.00
    $370.00
    $370.00
    Earn 5% Cashback
    ( plated ) Skin Science
  • SkinCeuticals H.A. Intensifier Multi-Glycan SkinCeuticals H.A. Intensifier Multi-Glycan

    SkinCeuticals H.A. Intensifier Multi-Glycan

    $175.00
    $175.00
    $175.00
    Earn 5% Cashback
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  • DP Dermaceuticals HylaActive DP Dermaceuticals HylaActive

    DP Dermaceuticals HylaActive

    $130.00
    $130.00
    $130.00
    Earn 5% Cashback
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  • Alumier EvenTone

    Alumier EvenTone

    $140.00
    $140.00
    Earn 5% Cashback
    All Products
  • Alumier Rejuvenating Collection - Normal/Dry

    Alumier Rejuvenating Collection - Normal/Dry

    $551.00
    $551.00
    Earn 5% Cashback
    All Products
  • ZO Skin Health 10% Vitamin C Self-Activating ZO Skin Health 10% Vitamin C Self-Activating

    ZO Skin Health 10% Vitamin C Self-Activating

    From $65.00
    From $65.00
    Earn 5% Cashback
    All Products
  • GlyMed Restoring Fulvic Elixir GlyMed Restoring Fulvic Elixir

    GlyMed Restoring Fulvic Elixir

    $93.00
    $93.00
    Earn 5% Cashback
    All Products

The Complete Guide to Serums & Oils

Serums are where visible change happens, delivering potent, targeted actives, antioxidants, retinol, peptides and brighteners, in concentrations creams cannot match. WeDoSkin carries medical-grade serums and oils from the professional brands clinics trust.

Browse best-selling serums below with live Canadian pricing, organised so you can find the right active for your concern.

🧪

High-Potency Actives

Concentrated vitamin C, retinol, peptides and growth factors.

🎯

Targeted Treatment

Choose a serum by concern: aging, pigment, redness or hydration.

🪶

Layer-Friendly

Lightweight textures absorb fast and layer under moisturiser.

🇨🇦

Authorized & Authentic

Fresh, correctly stored, sourced directly from the manufacturer.

The Science Behind Serums & Oils

How Serums & Oils's key actives work — and why formulation and delivery matter as much as the ingredient itself.

AM

Antioxidant Serums

Morning vitamin C and antioxidant serums defend against daytime free radicals.

PM

Retinol & Renewal

Evening retinol and resurfacing serums drive cell turnover while you sleep.

Hydrate

Hyaluronic & Soothing

Hydrating and calming serums layer with actives to support the barrier.

These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Serums & Oils Bestsellers

The most-loved Serums & Oils products at WeDoSkin. Tap any product to shop.

Alumier Ultimate Boost SerumAlumier Ultimate Boost Serum$141.00Shop now →SkinCeuticals C E Ferulic — New 2026 FormulaSkinCeuticals C E Ferulic — New 2026 Formula$230.00Shop now →Alumier Retinol Resurfacing Serum 1.0%Alumier Retinol Resurfacing Serum 1.0%$153.00Shop now →Vivier C E PeptidesVivier C E Peptides$222.00Shop now →Alumier Intellibright ComplexAlumier Intellibright Complex$136.00Shop now →Alumier Alumience A.G.E.™Alumier Alumience A.G.E.™$176.00Shop now →

Shop the Full Serums & Oils Range

Browse every Serums & Oils product by category, with live Canadian pricing.

Hair Repair
( plated )™ Hair Science Hair Serum$530.00XYON Revitalize Hair-Boosting Serum for Women$72.00
Programs & Kits
Alumier Rejuvenating Collection - Normal/Dry$551.00
Retinols
Alumier Retinol Resurfacing Serum 1.0%$153.00Alumier Retinol Resurfacing Serum 0.5%$139.00Alumier Retinol Resurfacing Serum 0.25%$118.50
Serums, Oils & Concentrates
Alastin C-RADICAL Defense Antioxidant Serum$218.00Alastin A-Luminate Brightening Serum$240.00Alumier Ultimate Boost Serum$141.00SkinCeuticals C E Ferulic — New 2026 Formula$230.00Alumier Intellibright Complex$136.00Alumier Calm-R®$158.00SkinCeuticals P-TIOX — Needle-Free Anti-Wrinkle Serum$200.00Alumier Alumience A.G.E.™$176.00Alumier AHA Renewal Serum$119.00Alumier Acne Balancing Serum$103.00( plated )™ Skin Science Intense Serum$370.00SkinCeuticals H.A. Intensifier Multi-Glycan$175.00DP Dermaceuticals HylaActive$130.00Alumier EvenTone$140.00ZO Skin Health 10% Vitamin C Self-Activating$65.00GlyMed Restoring Fulvic Elixir$93.00

How to Choose What's Right for You

New to Serums & Oils? Start with your primary concern — here's where most people begin.

By Active

Vitamin CRetinolHyaluronic Acid

By Goal

Anti-AgingHyperpigmentationRedness

Serums & Oils: Frequently Asked Questions

What does a face serum do?

A face serum delivers a high concentration of active ingredients, like vitamin C, retinol or hyaluronic acid, deep into the skin to target specific concerns more powerfully than a moisturizer.

In what order do I apply serums?

Apply serums after cleansing and before moisturizer, from thinnest to thickest texture. A common approach is an antioxidant serum in the morning and a retinol or treatment serum at night.

Can I use more than one serum?

Yes, but layer thoughtfully. Water-based serums go before oil-based ones, and some actives like vitamin C and retinol are often split between morning and night to reduce irritation.

What is the best anti-aging serum?

For aging, vitamin C serums like SkinCeuticals C E Ferulic protect by day and retinol serums renew by night. Peptide and growth-factor serums add firmness. The best choice depends on your skin's tolerance and goals.

Are facial oils good for oily skin?

Certain lightweight, non-comedogenic oils can balance oily skin, but those prone to congestion often prefer gel serums. Patch-test and introduce oils gradually.

How long until a serum shows results?

Hydrating serums work immediately, while treatment serums like retinol and vitamin C typically show visible results over 8 to 12 weeks of consistent use.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

Serum guidance here reflects standard dermatological principles on active ingredients and layering. As a Preferred Authorized Retailer, WeDoSkin stores and ships every formula correctly so actives stay potent. This is educational and not a substitute for personalized medical advice.

Read about our medical-review standards →
Last reviewed June 10, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

Explore Related Concerns & Ingredients

The concern and ingredient hubs Serums & Oils products most often appear in at WeDoSkin.

IngredientVitamin CExplore →IngredientHyaluronic AcidExplore →IngredientRetinolExplore →IngredientPeptidesExplore →IngredientNiacinamideExplore →

Why Canadians Choose WeDoSkin

Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.

Authorized & AuthenticEvery product is sourced directly from the brand — never grey-market — with full manufacturer warranty.
100,000+ Happy CustomersA trusted Canadian destination for medical-grade skincare, with thousands of verified reviews on Trustpilot, Google and Judge.me.
Rewards That Never ExpireEarn 5–20% cashback with no dated points and no minimum to redeem — more rewarding than typical points programs.
100-Day ReturnsReturn unopened products for a full 100 days, or opened products for 45 days through BuySure.
Free Shipping Over $65Fast, Canada-wide delivery, with complimentary samples included in every order.
45+ Brands, 3,000+ ProductsFrom ZO Skin Health and SkinCeuticals to Vivier, AlumierMD and dozens more — plus complimentary clinical guidance.

Why shop with WeDoSkin →

Questions about Serums & Oils?

Connect with a WeDoSkin clinical expert for a complimentary consultation.

Contact Our Skincare Experts