Best Medical-Grade Serums in Canada
Serums are the treatment engine of a routine, delivering high concentrations of actives like vitamin C, retinol, peptides and hyaluronic acid deep into the skin. The best approach is to layer a targeted serum after cleansing and before moisturiser, choosing actives matched to your main concern. Shop medical-grade serums and facial oils from professional brands including SkinCeuticals, AlumierMD, Vivier, ZO Skin Health and iS Clinical — authentic and authorized in Canada.
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SkinCeuticals Phyto Corrective GelAll Products
SkinCeuticals Phyto Corrective Gel
- Regular price
- $115.00
- Sale price
- $115.00
- Regular price
- $115.00
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SkinCeuticals Hydrating B5 GelAll Products
SkinCeuticals Hydrating B5 Gel
- Regular price
- $125.00
- Sale price
- $125.00
- Regular price
- $125.00
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iS Clinical Retinol + Emulsion 0.3All Products
iS Clinical Retinol + Emulsion 0.3
- Regular price
- $149.00
- Sale price
- $149.00
- Regular price
- $149.00
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iS Clinical Active SerumAll Products
iS Clinical Active Serum
- Regular price
- $204.00
- Sale price
- $204.00
- Regular price
- $204.00
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iS Clinical Hydra-Cool SerumAll Products
iS Clinical Hydra-Cool Serum
- Regular price
- $142.00
- Sale price
- $142.00
- Regular price
- $142.00
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ZO Skin Health Illuminating AOX SerumAll Products
ZO Skin Health Illuminating AOX Serum
- Regular price
- $235.00
- Sale price
- $235.00
- Regular price
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iS Clinical Pro-Health Serum Advanced+All Products
iS Clinical Pro-Health Serum Advanced+
- Regular price
- $226.00
- Sale price
- $226.00
- Regular price
- $226.00
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Epicutis Lipid SerumAll Products
Epicutis Lipid Serum
- Regular price
- $300.00
- Sale price
- $300.00
- Regular price
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BABOR 10D Hyaluronic Acid Ampoule Serum ConcentrateAll Products
BABOR 10D Hyaluronic Acid Ampoule Serum Concentrate
- Regular price
- $54.76
- Sale price
- $54.76
- Regular price
- $39.97
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BABOR Radiance Ampoule Serum ConcentrateAll Products
BABOR Radiance Ampoule Serum Concentrate
- Regular price
- $65.00
- Sale price
- $65.00
- Regular price
- $65.00
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YonKa Advanced Optimizer SerumAll Products
YonKa Advanced Optimizer Serum
- Regular price
- $142.00
- Sale price
- $142.00
- Regular price
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COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30All Products
COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30
- Regular price
- $81.00
- Sale price
- $81.00
- Regular price
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ZO Skin Health RozatrolAll Products
ZO Skin Health Rozatrol
- Regular price
- From $62.00
- Sale price
- From $62.00
- Regular price
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Vivier Ultimage™All Products
Vivier Ultimage™
- Regular price
- $166.00
- Sale price
- $166.00
- Regular price
- $166.00
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iS Clinical Youth Eye ComplexAll Products
iS Clinical Youth Eye Complex
- Regular price
- $144.50
- Sale price
- $144.50
- Regular price
- $144.50
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XYON Defend Hair & Scalp Serum for MenAll Products
XYON Defend Hair & Scalp Serum for Men
- Regular price
- $72.00
- Sale price
- $72.00
- Regular price
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SkinBetter Alto Advanced Defense and Repair SerumAll Products
SkinBetter Alto Advanced Defense and Repair Serum
- Regular price
- $290.00
- Sale price
- $290.00
- Regular price
- $290.00
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SkinBetter AlphaRet Clearing SerumAll Products
SkinBetter AlphaRet Clearing Serum
- Regular price
- $220.00
- Sale price
- $220.00
- Regular price
- $220.00
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BABOR Rejuvenation Ampoule Serum ConcentrateAll Products
BABOR Rejuvenation Ampoule Serum Concentrate
- Regular price
- $65.00
- Sale price
- $65.00
- Regular price
- $65.00
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GM Collin Ceramide Comfort Serum - 80 CapsulesAll Products
GM Collin Ceramide Comfort Serum - 80 Capsules
- Regular price
- $142.00
- Sale price
- $142.00
- Regular price
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GM Collin Ceramide Comfort Serum - 20 CapsulesAll Products
GM Collin Ceramide Comfort Serum - 20 Capsules
- Regular price
- $40.00
- Sale price
- $40.00
- Regular price
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Colorescience Total Eye® Concentrate Serum RollerballAll Products
Colorescience Total Eye® Concentrate Serum Rollerball
- Regular price
- $98.00
- Sale price
- $98.00
- Regular price
- $98.00
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Vivier Radiance SerumAll Products
Vivier Radiance Serum
- Regular price
- $181.00
- Sale price
- $181.00
- Regular price
- $181.00
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The Complete Guide to Serums & Oils
Serums are where visible change happens, delivering potent, targeted actives, antioxidants, retinol, peptides and brighteners, in concentrations creams cannot match. WeDoSkin carries medical-grade serums and oils from the professional brands clinics trust.
Browse best-selling serums below with live Canadian pricing, organised so you can find the right active for your concern.
High-Potency Actives
Concentrated vitamin C, retinol, peptides and growth factors.
Targeted Treatment
Choose a serum by concern: aging, pigment, redness or hydration.
Layer-Friendly
Lightweight textures absorb fast and layer under moisturiser.
Authorized & Authentic
Fresh, correctly stored, sourced directly from the manufacturer.
The Science Behind Serums & Oils
How Serums & Oils's key actives work — and why formulation and delivery matter as much as the ingredient itself.
Antioxidant Serums
Morning vitamin C and antioxidant serums defend against daytime free radicals.
Retinol & Renewal
Evening retinol and resurfacing serums drive cell turnover while you sleep.
Hyaluronic & Soothing
Hydrating and calming serums layer with actives to support the barrier.
These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Serums & Oils Bestsellers
The most-loved Serums & Oils products at WeDoSkin. Tap any product to shop.
Alumier Ultimate Boost Serum$141.00Shop now →
SkinCeuticals C E Ferulic$230.00Shop now →
Alumier Retinol Resurfacing Serum 1.0%$153.00Shop now →
Vivier C E Peptides$222.00Shop now →
Alumier Intellibright Complex$136.00Shop now →
Alumier Alumience A.G.E.™$176.00Shop now →Shop the Full Serums & Oils Range
Browse every Serums & Oils product by category, with live Canadian pricing.
How to Choose What's Right for You
New to Serums & Oils? Start with your primary concern — here's where most people begin.
Serums & Oils: Frequently Asked Questions
What does a face serum do?
A face serum delivers a high concentration of active ingredients, like vitamin C, retinol or hyaluronic acid, deep into the skin to target specific concerns more powerfully than a moisturizer.
In what order do I apply serums?
Apply serums after cleansing and before moisturizer, from thinnest to thickest texture. A common approach is an antioxidant serum in the morning and a retinol or treatment serum at night.
Can I use more than one serum?
Yes, but layer thoughtfully. Water-based serums go before oil-based ones, and some actives like vitamin C and retinol are often split between morning and night to reduce irritation.
What is the best anti-aging serum?
For aging, vitamin C serums like SkinCeuticals C E Ferulic protect by day and retinol serums renew by night. Peptide and growth-factor serums add firmness. The best choice depends on your skin's tolerance and goals.
Are facial oils good for oily skin?
Certain lightweight, non-comedogenic oils can balance oily skin, but those prone to congestion often prefer gel serums. Patch-test and introduce oils gradually.
How long until a serum shows results?
Hydrating serums work immediately, while treatment serums like retinol and vitamin C typically show visible results over 8 to 12 weeks of consistent use.
Serum guidance here reflects standard dermatological principles on active ingredients and layering. As a Preferred Authorized Retailer, WeDoSkin stores and ships every formula correctly so actives stay potent. This is educational and not a substitute for personalized medical advice.
Explore Related Concerns & Ingredients
The concern and ingredient hubs Serums & Oils products most often appear in at WeDoSkin.
Why Canadians Choose WeDoSkin
Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.
Questions about Serums & Oils?
Connect with a WeDoSkin clinical expert for a complimentary consultation.
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