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Best Medical-Grade Serums in Canada

Serums are the treatment engine of a routine, delivering high concentrations of actives like vitamin C, retinol, peptides and hyaluronic acid deep into the skin. The best approach is to layer a targeted serum after cleansing and before moisturiser, choosing actives matched to your main concern. Shop medical-grade serums and facial oils from professional brands including SkinCeuticals, AlumierMD, Vivier, ZO Skin Health and iS Clinical — authentic and authorized in Canada.

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  • Biojuve Biome Support Complex Biojuve Biome Support Complex
    $80.00 Off

    Biojuve Biome Support Complex

    $119.99
    $119.99
    $199.99
    Earn 5% Cashback
    All Products
  • BIOJUVE Living Biome Essentials Duo BIOJUVE Living Biome Essentials Duo
    $116.00 Off

    BIOJUVE Living Biome Essentials Duo

    $173.99
    $173.99
    $289.99
    Earn 5% Cashback
    All Products
  • Alumier Ultimate Boost Serum Alumier Ultimate Boost Serum

    Alumier Ultimate Boost Serum

    $141.00
    $141.00
    Earn 5% Cashback
    All Products
  • Alumier Retinol Resurfacing Serum 1.0% Alumier Retinol Resurfacing Serum 1.0%

    Alumier Retinol Resurfacing Serum 1.0%

    $153.00
    $153.00
    Earn 5% Cashback
    All Products
  • SkinCeuticals C E Ferulic SkinCeuticals C E Ferulic

    SkinCeuticals C E Ferulic

    $230.00
    $230.00
    $230.00
    Earn 5% Cashback
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  • Alumier Calm-R® Alumier Calm-R®

    Alumier Calm-R®

    $158.00
    $158.00
    Earn 5% Cashback
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  • Alumier Intellibright Complex Alumier Intellibright Complex

    Alumier Intellibright Complex

    $136.00
    $136.00
    Earn 5% Cashback
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  • Alumier Retinol Resurfacing Serum 0.5% Alumier Retinol Resurfacing Serum 0.5%

    Alumier Retinol Resurfacing Serum 0.5%

    $139.00
    $139.00
    Earn 5% Cashback
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  • SkinCeuticals P-TIOX SkinCeuticals P-TIOX

    SkinCeuticals P-TIOX

    $200.00
    $200.00
    $200.00
    Earn 5% Cashback
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  • Vivier C E Peptides Vivier C E Peptides

    Vivier C E Peptides

    $222.00
    $222.00
    $222.00
    Earn 5% Cashback
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  • Alumier Retinol Resurfacing Serum 0.25% Alumier Retinol Resurfacing Serum 0.25%

    Alumier Retinol Resurfacing Serum 0.25%

    $118.50
    $118.50
    Earn 5% Cashback
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  • Alumier Acne Balancing Serum Alumier Acne Balancing Serum

    Alumier Acne Balancing Serum

    $103.00
    $103.00
    Earn 5% Cashback
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  • Alumier AHA Renewal Serum Alumier AHA Renewal Serum

    Alumier AHA Renewal Serum

    $119.00
    $119.00
    Earn 5% Cashback
    AHAs (Glycolic Acid/Lactic Acid)
  • Alumier Alumience A.G.E.™ Alumier Alumience A.G.E.™

    Alumier Alumience A.G.E.™

    $176.00
    $176.00
    Earn 5% Cashback
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  • SkinCeuticals H.A. Intensifier Multi-Glycan SkinCeuticals H.A. Intensifier Multi-Glycan

    SkinCeuticals H.A. Intensifier Multi-Glycan

    $175.00
    $175.00
    $175.00
    Earn 5% Cashback
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  • GMC Medical Intense Moisture Serum

    GMC Medical Intense Moisture Serum

    $120.00
    $120.00
    Earn 5% Cashback
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  • Alumier Rejuvenating Collection - Normal/Dry Alumier Rejuvenating Collection - Normal/Dry

    Alumier Rejuvenating Collection - Normal/Dry

    $551.00
    $551.00
    Earn 5% Cashback
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  • ZO Skin Health 10% Vitamin C Self-Activating ZO Skin Health 10% Vitamin C Self-Activating

    ZO Skin Health 10% Vitamin C Self-Activating

    From $65.00
    From $65.00
    Earn 5% Cashback
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  • ( plated )™ Skin Science Intense Serum ( plated )™ Skin Science Intense Serum

    ( plated )™ Skin Science Intense Serum

    $370.00
    $370.00
    $370.00
    Earn 5% Cashback
    ( plated )™ Skin Science
  • COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30 COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30

    COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30

    $81.00
    $81.00
    Earn 5% Cashback
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  • BABOR 10D Hyaluronic Acid Ampoule Serum Concentrate BABOR 10D Hyaluronic Acid Ampoule Serum Concentrate

    BABOR 10D Hyaluronic Acid Ampoule Serum Concentrate

    $54.76
    $54.76
    $39.97
    Earn 5% Cashback
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  • Alumier EvenTone

    Alumier EvenTone

    $140.00
    $140.00
    Earn 5% Cashback
    All Products
  • GlyMed Restoring Fulvic Elixir GlyMed Restoring Fulvic Elixir

    GlyMed Restoring Fulvic Elixir

    $93.00
    $93.00
    Earn 5% Cashback
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The Complete Guide to Serums & Oils

Serums are where visible change happens, delivering potent, targeted actives, antioxidants, retinol, peptides and brighteners, in concentrations creams cannot match. WeDoSkin carries medical-grade serums and oils from the professional brands clinics trust.

Browse best-selling serums below with live Canadian pricing, organised so you can find the right active for your concern.

🧪

High-Potency Actives

Concentrated vitamin C, retinol, peptides and growth factors.

🎯

Targeted Treatment

Choose a serum by concern: aging, pigment, redness or hydration.

🪶

Layer-Friendly

Lightweight textures absorb fast and layer under moisturiser.

🇨🇦

Authorized & Authentic

Fresh, correctly stored, sourced directly from the manufacturer.

The Science Behind Serums & Oils

How Serums & Oils's key actives work — and why formulation and delivery matter as much as the ingredient itself.

AM

Antioxidant Serums

Morning vitamin C and antioxidant serums defend against daytime free radicals.

PM

Retinol & Renewal

Evening retinol and resurfacing serums drive cell turnover while you sleep.

Hydrate

Hyaluronic & Soothing

Hydrating and calming serums layer with actives to support the barrier.

These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Serums & Oils Bestsellers

The most-loved Serums & Oils products at WeDoSkin. Tap any product to shop.

Alumier Ultimate Boost SerumAlumier Ultimate Boost Serum$141.00Shop now →SkinCeuticals C E FerulicSkinCeuticals C E Ferulic$230.00Shop now →Alumier Retinol Resurfacing Serum 1.0%Alumier Retinol Resurfacing Serum 1.0%$153.00Shop now →Vivier C E PeptidesVivier C E Peptides$222.00Shop now →Alumier Intellibright ComplexAlumier Intellibright Complex$136.00Shop now →Alumier Alumience A.G.E.™Alumier Alumience A.G.E.™$176.00Shop now →

Shop the Full Serums & Oils Range

Browse every Serums & Oils product by category, with live Canadian pricing.

Classic Suncreens
COOLA Dew Good Illuminating Serum Sunscreen with Probiotic Technology SPF 30$81.00
Programs & Kits
Alumier Rejuvenating Collection - Normal/Dry$551.00
Retinols
Alumier Retinol Resurfacing Serum 1.0%$153.00Alumier Retinol Resurfacing Serum 0.5%$139.00Alumier Retinol Resurfacing Serum 0.25%$118.50
Serum
BIOJUVE Living Biome Essentials Duo$173.99
Serums, Oils & Concentrates
Biojuve Biome Support Complex$119.99Alumier Ultimate Boost Serum$141.00SkinCeuticals C E Ferulic$230.00Alumier Calm-R®$158.00Alumier Intellibright Complex$136.00SkinCeuticals P-TIOX$200.00Alumier Acne Balancing Serum$103.00Alumier AHA Renewal Serum$119.00Alumier Alumience A.G.E.™$176.00SkinCeuticals H.A. Intensifier Multi-Glycan$175.00GMC Medical Intense Moisture Serum$120.00ZO Skin Health 10% Vitamin C Self-Activating$65.00( plated )™ Skin Science Intense Serum$370.00BABOR 10D Hyaluronic Acid Ampoule Serum Concentrate$54.76Alumier EvenTone$140.00GlyMed Restoring Fulvic Elixir$93.00

How to Choose What's Right for You

New to Serums & Oils? Start with your primary concern — here's where most people begin.

By Active

Vitamin CRetinolHyaluronic Acid

By Goal

Anti-AgingHyperpigmentationRedness

Serums & Oils: Frequently Asked Questions

What does a face serum do?

A face serum delivers a high concentration of active ingredients, like vitamin C, retinol or hyaluronic acid, deep into the skin to target specific concerns more powerfully than a moisturizer.

In what order do I apply serums?

Apply serums after cleansing and before moisturizer, from thinnest to thickest texture. A common approach is an antioxidant serum in the morning and a retinol or treatment serum at night.

Can I use more than one serum?

Yes, but layer thoughtfully. Water-based serums go before oil-based ones, and some actives like vitamin C and retinol are often split between morning and night to reduce irritation.

What is the best anti-aging serum?

For aging, vitamin C serums like SkinCeuticals C E Ferulic protect by day and retinol serums renew by night. Peptide and growth-factor serums add firmness. The best choice depends on your skin's tolerance and goals.

Are facial oils good for oily skin?

Certain lightweight, non-comedogenic oils can balance oily skin, but those prone to congestion often prefer gel serums. Patch-test and introduce oils gradually.

How long until a serum shows results?

Hydrating serums work immediately, while treatment serums like retinol and vitamin C typically show visible results over 8 to 12 weeks of consistent use.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

Serum guidance here reflects standard dermatological principles on active ingredients and layering. As a Preferred Authorized Retailer, WeDoSkin stores and ships every formula correctly so actives stay potent. This is educational and not a substitute for personalized medical advice.

Read about our medical-review standards →
Last reviewed June 10, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

Explore Related Concerns & Ingredients

The concern and ingredient hubs Serums & Oils products most often appear in at WeDoSkin.

IngredientVitamin CExplore →IngredientHyaluronic AcidExplore →IngredientRetinolExplore →IngredientPeptidesExplore →IngredientNiacinamideExplore →

Why Canadians Choose WeDoSkin

Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.

Authorized & AuthenticEvery product is sourced directly from the brand — never grey-market — with full manufacturer warranty.
100,000+ Happy CustomersA trusted Canadian destination for medical-grade skincare, with thousands of verified reviews on Trustpilot, Google and Judge.me.
Rewards That Never ExpireEarn 5–20% cashback with no dated points and no minimum to redeem — more rewarding than typical points programs.
100-Day ReturnsReturn unopened products for a full 100 days, or opened products for 45 days through BuySure.
Free Shipping Over $65Fast, Canada-wide delivery, with complimentary samples included in every order.
45+ Brands, 3,000+ ProductsFrom ZO Skin Health and SkinCeuticals to Vivier, AlumierMD and dozens more — plus complimentary clinical guidance.

Why shop with WeDoSkin →

Questions about Serums & Oils?

Connect with a WeDoSkin clinical expert for a complimentary consultation.

Contact Our Skincare Experts