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Best Medical-Grade Serums in Canada

Serums are the treatment engine of a routine, delivering high concentrations of actives like vitamin C, retinol, peptides and hyaluronic acid deep into the skin. The best approach is to layer a targeted serum after cleansing and before moisturiser, choosing actives matched to your main concern. Shop medical-grade serums and facial oils from professional brands including SkinCeuticals, AlumierMD, Vivier, ZO Skin Health and iS Clinical — authentic and authorized in Canada.

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  • iS Clinical Brightening Complex iS Clinical Brightening Complex

    iS Clinical Brightening Complex

    $219.00
    $219.00
    $219.00
    Earn 5% Cashback
    All Products
  • C Eye Serum Advance+ C Eye Serum Advance+

    C Eye Serum Advance+

    $98.00
    $98.00
    $98.00
    Earn 5% Cashback
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  • COOLA Organic Sunless Gradual Face Serum COOLA Organic Sunless Gradual Face Serum

    COOLA Organic Sunless Gradual Face Serum

    $85.00
    $85.00
    Earn 5% Cashback
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  • DP Dermaceuticals Brite Lite Serum DP Dermaceuticals Brite Lite Serum

    DP Dermaceuticals Brite Lite Serum

    $176.69
    $176.69
    $128.97
    Earn 5% Cashback
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  • DP Dermaceuticals Antioxidant Cocktail Serum DP Dermaceuticals Antioxidant Cocktail Serum

    DP Dermaceuticals Antioxidant Cocktail Serum

    $164.36
    $164.36
    $119.97
    Earn 5% Cashback
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  • Colorescience Pep Up Collagen Boost Face & Neck Serum Colorescience Pep Up Collagen Boost Face & Neck Serum

    Colorescience Pep Up Collagen Boost Face & Neck Serum

    $229.90
    $229.90
    Earn 5% Cashback
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  • ZO Skin Health Instant Pore Refiner ZO Skin Health Instant Pore Refiner

    ZO Skin Health Instant Pore Refiner

    $86.00
    $86.00
    Earn 5% Cashback
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  • Vivier Kine-C Vivier Kine-C

    Vivier Kine-C

    $198.00
    $198.00
    $198.00
    Earn 5% Cashback
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  • SkinCeuticals P-TIOX Anti-Wrinkle Cream - Travel Size SkinCeuticals P-TIOX Anti-Wrinkle Cream - Travel Size

    SkinCeuticals P-TIOX Anti-Wrinkle Cream - Travel Size

    $95.00
    $95.00
    Earn 5% Cashback
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  • Forlle'd Hyalogy α Forlle'd Hyalogy α

    Forlle'd Hyalogy α

    $420.00
    $420.00
    Earn 5% Cashback
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  • Obagi Professional-C® Serum 20% Obagi Professional-C® Serum 20%

    Obagi Professional-C® Serum 20%

    $222.00
    $222.00
    Earn 5% Cashback
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  • Eminence Citrus & Kale Potent C + E Serum Eminence Citrus & Kale Potent C + E Serum
    $23.60 Off

    Eminence Citrus & Kale Potent C + E Serum

    $94.40
    $94.40
    $118.00
    Earn 10% Cashback
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  • Eminence Marine Flower Peptide Lip Serum Eminence Marine Flower Peptide Lip Serum
    $11.80 Off

    Eminence Marine Flower Peptide Lip Serum

    $47.20
    $47.20
    $59.00
    Earn 10% Cashback
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  • Eminence Neroli Age Corrective Eye Serum
    $14.80 Off

    Eminence Neroli Age Corrective Eye Serum

    $59.20
    $59.20
    $74.00
    Earn 10% Cashback
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  • Eminence Eight Greens Youth Serum
    $24.00 Off

    Eminence Eight Greens Youth Serum

    $35.00
    $35.00
    $59.00
    Earn 10% Cashback
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  • PCA Skin Total Strength Serum PCA Skin Total Strength Serum
    $81.00 Off

    PCA Skin Total Strength Serum

    $81.00
    $81.00
    $162.00
    Earn 5% Cashback
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  • PCA Skin Rejuvenating Serum PCA Skin Rejuvenating Serum
    $77.50 Off

    PCA Skin Rejuvenating Serum

    $77.50
    $77.50
    $155.00
    Earn 5% Cashback
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  • PCA Skin Hydrating Serum PCA Skin Hydrating Serum
    $77.50 Off

    PCA Skin Hydrating Serum

    $77.50
    $77.50
    $155.00
    Earn 5% Cashback
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  • Omnilux Noni Balancing Serum Omnilux Noni Balancing Serum
    $14.20 Off

    Omnilux Noni Balancing Serum

    $56.80
    $56.80
    $71.00
    Earn 5% Cashback
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  • TiZO® Photoceutical Advanced Vitamin C & E Serum TiZO® Photoceutical Advanced Vitamin C & E Serum

    TiZO® Photoceutical Advanced Vitamin C & E Serum

    $149.00
    $149.00
    $149.00
    Earn 5% Cashback
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  • EltaMD Skin Recovery Serum EltaMD Skin Recovery Serum
    $23.70 Off

    EltaMD Skin Recovery Serum

    $134.30
    $134.30
    $158.00
    Earn 5% Cashback
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  • Alastin Restorative Skin Complex with TriHex Technology™ Alastin Restorative Skin Complex with TriHex Technology™

    Alastin Restorative Skin Complex with TriHex Technology™

    $273.96
    $273.96
    $199.97
    Advanced Regenerative Skincare
  • iS Clinical Youth Complex iS Clinical Youth Complex

    iS Clinical Youth Complex

    $260.26
    $260.26
    $189.97
    Earn 5% Cashback
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The Complete Guide to Serums & Oils

Serums are where visible change happens, delivering potent, targeted actives, antioxidants, retinol, peptides and brighteners, in concentrations creams cannot match. WeDoSkin carries medical-grade serums and oils from the professional brands clinics trust.

Browse best-selling serums below with live Canadian pricing, organised so you can find the right active for your concern.

🧪

High-Potency Actives

Concentrated vitamin C, retinol, peptides and growth factors.

🎯

Targeted Treatment

Choose a serum by concern: aging, pigment, redness or hydration.

🪶

Layer-Friendly

Lightweight textures absorb fast and layer under moisturiser.

🇨🇦

Authorized & Authentic

Fresh, correctly stored, sourced directly from the manufacturer.

The Science Behind Serums & Oils

How Serums & Oils's key actives work — and why formulation and delivery matter as much as the ingredient itself.

AM

Antioxidant Serums

Morning vitamin C and antioxidant serums defend against daytime free radicals.

PM

Retinol & Renewal

Evening retinol and resurfacing serums drive cell turnover while you sleep.

Hydrate

Hyaluronic & Soothing

Hydrating and calming serums layer with actives to support the barrier.

These descriptions reflect how each ingredient category works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.

Serums & Oils Bestsellers

The most-loved Serums & Oils products at WeDoSkin. Tap any product to shop.

Alumier Ultimate Boost SerumAlumier Ultimate Boost Serum$141.00Shop now →SkinCeuticals C E FerulicSkinCeuticals C E Ferulic$230.00Shop now →Alumier Retinol Resurfacing Serum 1.0%Alumier Retinol Resurfacing Serum 1.0%$153.00Shop now →Vivier C E PeptidesVivier C E Peptides$222.00Shop now →Alumier Intellibright ComplexAlumier Intellibright Complex$136.00Shop now →Alumier Alumience A.G.E.™Alumier Alumience A.G.E.™$176.00Shop now →

Shop the Full Serums & Oils Range

Browse every Serums & Oils product by category, with live Canadian pricing.

Eyes, Neck & Lips
Colorescience Pep Up Collagen Boost Face & Neck Serum$229.90Eminence Marine Flower Peptide Lip Serum$47.20Eminence Neroli Age Corrective Eye Serum$59.20
Moisturizers
ZO Skin Health Instant Pore Refiner$86.00Alastin Restorative Skin Complex with TriHex Technology™$273.96iS Clinical Youth Complex$260.26
Retinols
iS Clinical Brightening Complex$219.00
Serums, Oils & Concentrates
C Eye Serum Advance+$98.00DP Dermaceuticals Brite Lite Serum$176.69DP Dermaceuticals Antioxidant Cocktail Serum$164.36Vivier Kine-C$198.00Forlle'd Hyalogy α$420.00Obagi Professional-C® Serum 20%$222.00Eminence Citrus & Kale Potent C + E Serum$94.40Eminence Eight Greens Youth Serum$35.00PCA Skin Total Strength Serum$81.00PCA Skin Rejuvenating Serum$77.50PCA Skin Hydrating Serum$77.50Omnilux Noni Balancing Serum$56.80TiZO® Photoceutical Advanced Vitamin C & E Serum$149.00EltaMD Skin Recovery Serum$134.30
Sunless Tan
COOLA Organic Sunless Gradual Face Serum$85.00
Travel Size
SkinCeuticals P-TIOX Anti-Wrinkle Cream - Travel Size$95.00

How to Choose What's Right for You

New to Serums & Oils? Start with your primary concern — here's where most people begin.

By Active

Vitamin CRetinolHyaluronic Acid

By Goal

Anti-AgingHyperpigmentationRedness

Serums & Oils: Frequently Asked Questions

What does a face serum do?

A face serum delivers a high concentration of active ingredients, like vitamin C, retinol or hyaluronic acid, deep into the skin to target specific concerns more powerfully than a moisturizer.

In what order do I apply serums?

Apply serums after cleansing and before moisturizer, from thinnest to thickest texture. A common approach is an antioxidant serum in the morning and a retinol or treatment serum at night.

Can I use more than one serum?

Yes, but layer thoughtfully. Water-based serums go before oil-based ones, and some actives like vitamin C and retinol are often split between morning and night to reduce irritation.

What is the best anti-aging serum?

For aging, vitamin C serums like SkinCeuticals C E Ferulic protect by day and retinol serums renew by night. Peptide and growth-factor serums add firmness. The best choice depends on your skin's tolerance and goals.

Are facial oils good for oily skin?

Certain lightweight, non-comedogenic oils can balance oily skin, but those prone to congestion often prefer gel serums. Patch-test and introduce oils gradually.

How long until a serum shows results?

Hydrating serums work immediately, while treatment serums like retinol and vitamin C typically show visible results over 8 to 12 weeks of consistent use.

Medically reviewed by Dr. J. Porter
Medical Reviewer, WeDoSkin Clinic

Serum guidance here reflects standard dermatological principles on active ingredients and layering. As a Preferred Authorized Retailer, WeDoSkin stores and ships every formula correctly so actives stay potent. This is educational and not a substitute for personalized medical advice.

Read about our medical-review standards →
Last reviewed June 10, 2026 · WeDoSkin Clinic, Calgary · Educational information, not a substitute for personalized medical advice.

Explore Related Concerns & Ingredients

The concern and ingredient hubs Serums & Oils products most often appear in at WeDoSkin.

IngredientVitamin CExplore →IngredientHyaluronic AcidExplore →IngredientRetinolExplore →IngredientPeptidesExplore →IngredientNiacinamideExplore →

Why Canadians Choose WeDoSkin

Trusted by more than 100,000 customers, WeDoSkin.ca is a Preferred Authorized Retailer of medical-grade skincare in Canada — 45+ professional brands and 3,000+ products, with cashback rewards that never expire, 100-day returns, free Canada-wide shipping over $65, and free samples in every order.

Authorized & AuthenticEvery product is sourced directly from the brand — never grey-market — with full manufacturer warranty.
100,000+ Happy CustomersA trusted Canadian destination for medical-grade skincare, with thousands of verified reviews on Trustpilot, Google and Judge.me.
Rewards That Never ExpireEarn 5–20% cashback with no dated points and no minimum to redeem — more rewarding than typical points programs.
100-Day ReturnsReturn unopened products for a full 100 days, or opened products for 45 days through BuySure.
Free Shipping Over $65Fast, Canada-wide delivery, with complimentary samples included in every order.
45+ Brands, 3,000+ ProductsFrom ZO Skin Health and SkinCeuticals to Vivier, AlumierMD and dozens more — plus complimentary clinical guidance.

Why shop with WeDoSkin →

Questions about Serums & Oils?

Connect with a WeDoSkin clinical expert for a complimentary consultation.

Contact Our Skincare Experts