NeoGenesis MB-1
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MB-1 is the NeoGenesis balancing probiotic mist, and NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria. Most microbiome skincare uses ferments or inactive extracts.
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Description
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Key Benefits
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How to use
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Ingredients
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Frequently Asked Questions
Description
Size: 30 mL / 120 mL
Skin Types: All skin types, including sensitive
Skin Concerns: Visible redness and reactive skin, blemish-prone and congested skin, sensitive skin, dry, itchy-feeling skin, oily skin, barrier support, all skin types
MB-1 is the NeoGenesis balancing probiotic mist, and it is unlike most microbiome skincare: instead of ferments or inactive extracts, it contains live nitrifying bacteria, delivered in a three-ingredient formula with water and sodium hyaluronate butyrate. NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria, designed to hydrate, support the skin barrier and help restore balance to skin that is blemish-prone, reactive or easily irritated.
The live bacteria help support a balanced skin microbiome through flora diversity and natural microbial competition, while sodium hyaluronate butyrate hydrates and delivers butyrate, a postbiotic associated with comfort and barrier support. Together they help calm the look of redness, breakouts, irritation and itch for a calmer, clearer-looking complexion. Shake well and spray it on as the very last step, after every other product, at least twice a day.
Watch: MB-1 explained
NeoGenesis made this short product video for MB-1, so you can see the texture, the application and where it fits in a routine before you buy.
Real results with MB-1
NeoGenesis publishes before and after photos from its professional partners. These cases used MB-1 as part of a NeoGenesis routine, and each caption lists every product involved.
Photos courtesy of NeoGenesis professional partners. Individual results vary.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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Let customers speak for us
Very soothing after microneedling. Apply liberally to calm any itching!
Favorite cleanser. I have purchased it 4 times already and I tried to switch to another brand and I always end up going back to this one. I have very sensitive skin and my pores get clogged very easily. This cream cleanser is soothing and does an excellent job cleansing my face. I use it in the morning and as a second cleanse at time. A little bit goes a long way and although it doesn’t have a scent, the experience of washing your face with it is so pleasant and satisfying. I am done trying new cleansers.
Favorite SPF. I have tried so many different SPF and brands. They would be too greasy and/or sting my eyes after a few hours and/or irritate my sensitive skin and/or clog my pores. I finally found the one! Is it lightweight, non greasy, protects very well, sweat resistant, doesn’t irritate my skin or clog my pores. On top of that a little bit goes a long way. This is my third bottle and my quest for the best SPF for my skin is finally over.
Très bien marché bien et j’achèterais surement un autre
I love this product, the Vivier Sheer SPF30 Mineral tinted sunscreen. I love the creamy easy to apply non scented cream that just glides and covers light skin imperfections. I will definitely re-order again.
I love this product!Used 0.3 before and increased to 0.5 with sude effects.
This cleanser polish is a povely
I’ve been using this product for a year and it’s the only thing that’s worked for my face to help it heal and clear up my skin. I’ve been trying a lot of other products and this one works! Highly recommend!
Very nice, i love this product
Beautiful packaging and looks very high end. I've been using for 2 weeks now and its easy to use. I like how it automatically turns off in 10 mins.
The perfect complement to my pigment control routine - with hydroquinone part of the year, and office laser treatments. This product is excellent, and works well layering. No pilling!
Love this formula! 10/10 great for mature skin
Love this brand already but this was my first time trying these products. A great deal getting them in this kit! My fave is the exfoliating polish, it is amazing! Feels so invigorating, and after my skin feels so soft and fresh.
Excellent product.face mask protection. I visited to Cusco where there is a very high altitude so that the sun radiation is extremely intense. The mask protection worked well!!
I’ve been using this for almost a decade! Love it!
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MB-1: the balancing probiotic mist with live bacteria
MB-1 is the NeoGenesis balancing probiotic mist, and NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria. Most microbiome skincare uses ferments or inactive extracts. MB-1 uses live nitrifying bacteria, in a formula of just three ingredients: water, the bacteria and sodium hyaluronate butyrate. It is designed to hydrate, support the skin barrier and help restore balance to blemish-prone, reactive and easily irritated skin, for a calmer, clearer-looking complexion.
The live bacteria help support a balanced skin microbiome by encouraging flora diversity and natural microbial competition. Sodium hyaluronate butyrate, a skin-native hyaluronic acid, hydrates and delivers butyrate, a postbiotic associated with comfort and barrier support. Together they help calm the look of redness, breakouts, irritation and itch. Shake well and spray it on as the last step of your routine, morning and evening at minimum, and as often as your skin wants during the day.
Live bacteria, not ferments
Live nitrifying bacteria support the skin's natural microbiome, in a format most probiotic skincare does not offer.
Three ingredients
Water, live nitrifying bacteria and sodium hyaluronate butyrate. Nothing else.
Calms and clears
Helps soothe the look of redness, itch and irritation while supporting a clearer-looking complexion.
Barrier and balance
Supports the skin's natural barrier and microbiome balance for resilience against environmental and internal stressors.
Key Ingredients & How They Work
The actives that drive Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin. — and what each one does for your skin.
The skin microbiome
An ecosystem of microorganisms lives on the surface of the skin. MB-1 is designed to help support a balanced microbiome as part of a daily routine.
Why live nitrifying bacteria
Live bacteria encourage flora diversity and natural microbial competition, which is how MB-1 helps maintain a balanced skin environment and calmer, more resilient skin.
Butyrate, a postbiotic
Sodium hyaluronate butyrate hydrates like hyaluronic acid and delivers butyrate, associated with calming the look of redness, improving comfort and supporting the barrier.
Handling a living formula
Because the bacteria are alive, MB-1 is shaken before use, stored at room temperature or cooler, kept out of direct sunlight and used within six months of opening.
These descriptions reflect how each ingredient works in general dermatological terms. Individual results vary, and skincare is not a substitute for professional medical advice.
Benefits of Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin.
What Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin. Pairs Well With
Build a complete routine — these pairings are most often recommended alongside Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin.. Tap any product to shop.
NeoGenesis Barrier Renewal Cream$35.00Shop now →
NeoGenesis Recovery$100.00Shop now →
NeoGenesis Intensive Moisturizer$30.00Shop now →
NeoGenesis Skin Serum$55.00Shop now →How to Use
- Shake well before each use.
- Spray on the skin after all other products have been applied, as the final step, morning and evening at minimum, or as needed during the day.
- Do not use on skin that is broken or open. Store at room temperature (max 25 C / 77 F) or cooler, away from direct sunlight, and use within 6 months of opening.
Who It's For
- Skin that is red, reactive or easily irritated
- Blemish-prone or congested skin, including oily skin
- Dry, itchy-feeling or sensitive skin
- Anyone who wants to support the skin barrier and microbiome as a final daily step
Sensitivity note: Made for all skin types, including sensitive and reactive skin, with a fragrance-free, three-ingredient formula. NeoGenesis advises not to use it on skin that is broken or open.
How Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin. Compares
Where Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin. sits relative to other options. The right fit depends on your skin and goals.
| Feature | NeoGenesis MB-1 | Other Facial Mists | Drugstore Mists |
|---|---|---|---|
| Probiotic format | Live nitrifying bacteria | Probiotic ferments or lysates (inactive) | Prebiotic sugars or ferment extracts |
| Ingredient list | Three ingredients: water, live bacteria, sodium hyaluronate butyrate | Long lists with preservatives and fragrance | Long lists with preservatives and fragrance |
| Hydration | Sodium hyaluronate butyrate, a skin-native hyaluronic acid with a postbiotic | Standard humectants | Standard humectants |
| Routine fit | Final step after all other products, twice daily or as needed | Varies | Varies |
Live probiotic bacteria in a three-ingredient mist: calmer, clearer-looking, better-balanced skin.: Frequently Asked Questions
What is NeoGenesis MB-1?
MB-1 is a balancing probiotic mist that NeoGenesis describes as the only microbiome spray formulated with live probiotic bacteria. It contains three ingredients: water, live nitrifying bacteria and sodium hyaluronate butyrate. It is designed to hydrate, support the skin barrier and help restore balance to blemish-prone, reactive and easily irritated skin for a calmer, clearer-looking complexion.
How do I use MB-1?
Shake well before each use. Spray MB-1 on the skin after all other products have been applied, so it is the final step of your routine. Use it at least twice a day, or as needed during the day. Do not use it on skin that is broken or open. Store at room temperature (max 25 C / 77 F) or cooler, out of direct sunlight, and use within 6 months of opening.
Who is MB-1 for?
NeoGenesis positions MB-1 for skin that is blemish-prone, reactive or easily irritated, for oily skin, sensitive skin and dry skin. It suits anyone dealing with the look of redness, breakouts, irritation or itch, and anyone who wants to support the skin barrier and microbiome as an everyday step. It is made for all skin types.
What is the difference between MB-1 and MB-2?
MB-1 is a lightweight microbiome mist made with live nitrifying bacteria to help maintain a balanced skin environment during the day. MB-2 Probiotic Balm combines multiple probiotic strains with nourishing botanical oils to help prevent moisture loss in the evening. Many people use both: MB-1 as the last step in the morning and MB-2 at night.
How is MB-1 different from other probiotic skincare?
Most microbiome products use probiotic ferments, lysates or other inactive ingredients. MB-1 features live bacteria designed to support the skin's natural microbiome through flora diversity and natural microbial competition, paired with sodium hyaluronate butyrate for hydration. That is also why it is stored carefully and used within six months of opening.
Can I use MB-1 with retinoids, acids or other serums?
Yes. MB-1 goes on after everything else, so apply your S2RM serum, any actives and your moisturizer first, then spray MB-1 as the final layer. NeoGenesis lists Barrier Renewal Cream, Recovery, Intensive Moisturizer and Skin Serum as its pairings. Because it is a living formula, give the products underneath a moment to absorb before misting.
Are there before and after photos for MB-1?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used MB-1 is shown above with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use MB-1?
Yes. The NeoGenesis product video above walks through MB-1, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
This page is reviewed under the medical oversight of the WeDoSkin Clinic in Calgary. As a Preferred Authorized Retailer, our clinical team works directly with these brands and handles these formulas every day. Information here is educational and not a substitute for personalized medical advice.
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